Material Safety Data Sheet
Revised: 11/18/2011
Replaces: 11/17/2011
Printed: 06/21/2013
Section 1 - Product Description
Product Name: Caffeine
Product Code(s): 85-1568, 85-1570
Size: 25 g, 100 g
Chemical Name: 1,3,7,-Trimethylxanthine
CAS Number: 58-08-2
Formula: C8H10N4O2
Synonyms: No-Doz, Coffeine, Theine
Distributor: Carolina Biological Supply Company, 2700 York Road, Burlington, NC 27215
Chemical Information: 800-227-1150 (8am-5pm (ET) M-F) Chemtrec 800-424-9300 (Transportation Spill Response 24
Section 2 - Hazard Identification
Emergency Overview: Harmful: danger of serious damage to health by prolonged exposure if swallowed.
Potential Health Effects:
May cause irritation.
Skin: May cause irritation to skin.
Ingestion: May cause gastrointestinal discomfort.
Inhalation: May cause irritation to respiratory tract.
Section 3 - Composition / Information on Ingredients
Principal Hazardous Components: Caffeine, anhydrous (CAS# 58-08-2) 100%
TLV units: N/A
PEL units: N/A
Section 4 - First Aid Measures
Emergency and First Aid Procedures:
Eyes - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.
Skin - After contact with skin, take off immediately all contaminated clothing, and wash immediately with plenty of water.
Ingestion - If swallowed, do not induce vomiting: seek medical advice immediately and show this container or label. If
swallowed, rinse mouth with water (only if the person is conscious).
Inhalation - In case of accident by inhalation: remove casualty to fresh air and keep at rest.
Section 5 - Firefighting Procedures
Flash Point (Method Used): > 93.3?C (CC)
NFPA Rating:
Health: 2
Fire: 1
Reactivity: 0
Extinguisher Media: Use media suitable to extinguish surrounding fire.
Flammable Limits in Air % by Volume: N/A
Autoignition Temperature: N/A
Special Firefighting Procedures: Firefighters should wear full protective equipment and NIOSH approved self-contained
Unusual Fire and Explosion Hazards: Fire or excessive heat may produce hazardous decomposition products.
Explosive when mixed with oxidising substances.
Section 6 - Spill or Leak Procedures
Steps to Take in Case Material Is Released or Spilled: Ventilate area of spill. Clean-up personnel should wear proper
protective equipment. Avoid creating dust. Sweep or scoop up and containerize for disposal.
Section 7 - Special Precautions
Precautions to Take in Handling or Storing: Avoid creating and inhaling dust.
Take off immediately all contaminated clothing. Keep container tightly closed in a cool, well-ventilated place.
Section 8 - Protection Information
Respiratory Protection (Specify Type): None needed under normal conditions of use with adequate ventilation. A
NIOSH/MSHA chemical cartridge respirator should be worn if PEL or TLV is exceeded.
Local Exhaust: Yes
Mechanical(General): Yes
Special: No
Other: No
Protective Gloves: Natural rubber, Neoprene, PVC or equivalent.
Eye Protection: Splash proof chemical safety goggles should be worn.
Other Protective Clothing or Equipment: Lab coat, apron, eye wash, safety shower.
Section 9 - Physical Data
Molecular Weight: 194.19
Melting Point: Sublimes at 238 ?C
Boiling Point: 178 ?C
Vapor Pressure: N/A
Vapor Density(Air=1): N/A
Specific Gravity (H2O=1): 1.23 at 18 ?C
Percent Volatile by Volume: N/A
Evaporation Rate (BuAc=1): N/A
Solubility in Water: Slightly Soluble
Appearance and Odor: White, odorless crystals.
Section 10 - Reactivity Data
Stability: Stable
Conditions to Avoid: Heat and sources of ignition.
Incompatibility (Materials to Avoid): Oxidizers, Bases,
Hazardous Decomposition Products: COx, NOx,
Hazardous Polymerization: Will not occur
Section 11 - Toxicity Data
Toxicity Data: orl-rat LD50 192 mg/kg
Effects of Overexposure:
Acute: See Section 2
Chronic: Mutation data cited. Reproductive data cited. Not listed as a carcinogen by IARC, NTP or OSHA.
Conditions Aggravated by Overexposure: Cardiovascular system
Target Organs: N/A
Primary Route(s) of Entry: Inhalation and ingestion.
Section 12 - Ecological Data
EPA Waste Numbers: N/A
Section 13 - Disposal Information
Waste Disposal Methods: Dispose in accordance with all applicable Federal, State and Local regulations. Always contact a
permitted waste disposer (TSD) to assure compliance.
Section 14 - Transport Information
DOT Proper Shipping Name: UN2811, Toxic solids, organic, n.o.s.(caffeine), 6.1, III
Section 15 - Regulatory Information
EPA TSCA Status: On TSCA Inventory
Hazard Category for SARA Section 311/312 Reporting: Acute
Name List:
Chemical Category:
CERCLA Section 103 RQ(lb.): Caffeine - No
RCRA Section 261.33: Caffeine - No
Section 16 - Additional Information
The information provided in this Material Safety Data Sheet represents a compilation of data drawn directly from various sources available to us. Carolina Biological Supply makes no representation or guarantee as to the suitability of this information to a particular application of the substance covered in the Material Safety Data Sheet. Any employer must carefully assess the applicability of any information contained herein in regards to the particular use to which the employer puts the material.
American Conference of Governmental Industrial Hygienists CAS Number Chemical Services Abstract NumberCERCLA Comprehensive Environmental Response, Compensation, and Liability Act International Agency of Research on Cancer Occupational Safety and Health Administration Superfund Amendments and Reauthorization Act


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