Section 1 - Chemical Product and Company Identification
MSDS Name: Ampicillin Catalog Numbers: S70151A Synonyms: 6-(D(-)-alpha-Aminophenylacetamido)penicillanic acid; Ampicin; Aminobenzylpenicillin. Company Identification: Fisher Scientific 1 Reagent Lane Fair Lawn, NJ 07410 For information, call: 201-796-7100 Emergency Number: 201-796-7100 For CHEMTREC assistance, call: 800-424-9300 For International CHEMTREC assistance, call: 703-527-3887
Section 2 - Composition, Information on Ingredients
Chemical Name EINECS/ELINCS EMERGENCY OVERVIEW
Appearance: white to off-white solid. Warning! Causes eye, skin, and respiratory tract irritation. May cause allergic respiratory and skin reaction. Target Organs: Respiratory system, eyes, skin. Potential Health Effects Eye: Causes eye irritation. Skin: Causes skin irritation. May cause skin sensitization, an allergic reaction, which becomes evident upon re-exposure to this material. May be harmful if absorbed through the skin. Ingestion: May cause gastrointestinal irritation with nausea, vomiting and diarrhea. May be
harmful if swallowed. May cause serious or fatal hypersensitivity (anaphylactic) reactions in some Inhalation: Causes respiratory tract irritation. May cause allergic respiratory reaction. May be harmful if inhaled. Chronic: No information found.
Eyes: Immediately flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid. Skin: Immediately flush skin with plenty of water for at least 15 minutes while removing contaminated clothing and shoes. Get medical aid if irritation develops or persists. Wash clothing before reuse. Ingestion: Do not induce vomiting. If victim is conscious and alert, give 2-4 cupfuls of milk or water. Get medical aid. Inhalation: Remove from exposure and move to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid. Notes to Physician: Treat symptomatically and supportively.
General Information: As in any fire, wear a self-contained breathing apparatus in pressure-demand, MSHA/NIOSH (approved or equivalent), and full protective gear. During a fire, irritating and highly toxic gases may be generated by thermal decomposition or combustion. Extinguishing Media: Use water spray, dry chemical, carbon dioxide, or appropriate foam. Flash Point: Not applicable. Autoignition Temperature: Not applicable. Explosion Limits, Lower:Not available. Upper: Not available. NFPA Rating: (estimated) Health: 2; Flammability: 0; Instability: 0
General Information: Use proper personal protective equipment as indicated in Section 8. Spills/Leaks: Vacuum or sweep up material and place into a suitable disposal container. Clean up spills immediately, observing precautions in the Protective Equipment section. Avoid generating dusty conditions. Provide ventilation.
Handling: Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with skin and eyes. Keep container tightly closed. Avoid ingestion and inhalation. Storage: Store in a cool, dry, well-ventilated area away from incompatible substances.
Section 8 - Exposure Controls, Personal Protection
Engineering Controls: Facilities storing or utilizing this material should be equipped with an eyewash facility and a safety shower. Use adequate ventilation to keep airborne concentrations low. Exposure Limits Chemical Name OSHA - Final PELs
OSHA Vacated PELs: Ampicillin: No OSHA Vacated PELs are listed for this chemical. Personal Protective Equipment Eyes: Wear appropriate protective eyeglasses or chemical safety goggles as described by OSHA's eye and face protection regulations in 29 CFR 1910.133 or European Standard EN166. Skin: Wear appropriate protective gloves to prevent skin exposure. Clothing: Wear appropriate protective clothing to prevent skin exposure. Respirators: Follow the OSHA respirator regulations found in 29 CFR 1910.134 or European Standard EN 149. Use a NIOSH/MSHA or European Standard EN 149 approved respirator if exposure limits are exceeded or if irritation or other symptoms are experienced.
Section 9 - Physical and Chemical Properties
Physical State: Solid Appearance: white to off-white Odor: none reported pH: Not available. Vapor Pressure: Not applicable. Vapor Density: Not available. Evaporation Rate:Not applicable. Viscosity: Not applicable. Boiling Point: Not available. Freezing/Melting Point:202 deg C Decomposition Temperature:Not available. Solubility: Very soluble in water. Specific Gravity/Density:Not available. Molecular Formula:C16H19N3O4S Molecular Weight:349.4
Chemical Stability: Stable under normal temperatures and pressures. Conditions to Avoid: High temperatures, incompatible materials, dust generation, moisture. Incompatibilities with Other Materials: Strong oxidizers. Hazardous Decomposition Products: Carbon monoxide, oxides of nitrogen, oxides of sulfur, carbon dioxide. Hazardous Polymerization: Has not been reported.
RTECS#: CAS# 69-53-4: XH8350000; XH8360000 LD50/LC50: CAS# 69-53-4: Oral, mouse: LD50 = >5 gm/kg; Oral, mouse: LD50 = 15.2 gm/kg; Oral, rat: LD50 = 10 gm/kg; . Carcinogenicity: CAS# 69-53-4: Not listed by ACGIH, IARC, NTP, or CA Prop 65. Epidemiology: No information available. Teratogenicity: No information found Reproductive Effects: No information found Mutagenicity: No information found Neurotoxicity: No information found Other Studies:
Ecotoxicity: No data available. No information available. Environmental: No information reported. Physical: No information available. Other: None.
Chemical waste generators must determine whether a discarded chemical is classified as a hazardous waste. US EPA guidelines for the classification determination are listed in 40 CFR Parts 261.3. Additionally, waste generators must consult state and local hazardous waste regulations to ensure complete and accurate classification. RCRA P-Series: None listed. RCRA U-Series: None listed. Canada TDG Shipping Name: Hazard Class: UN Number: Packing Group:
TSCA CAS# 69-53-4 is not listed on the TSCA inventory. It is for research and development use only. Health & Safety Reporting List None of the chemicals are on the Health & Safety Reporting List. Chemical Test Rules None of the chemicals in this product are under a Chemical Test Rule. Section 12b None of the chemicals are listed under TSCA Section 12b. TSCA Significant New Use Rule None of the chemicals in this material have a SNUR under TSCA. CERCLA Hazardous Substances and corresponding RQs None of the chemicals in this material have an RQ. SARA Section 302 Extremely Hazardous Substances
None of the chemicals in this product have a TPQ. Section 313 No chemicals are reportable under Section 313. Clean Air Act: This material does not contain any hazardous air pollutants. This material does not contain any Class 1 Ozone depletors. This material does not contain any Class 2 Ozone depletors. Clean Water Act: None of the chemicals in this product are listed as Hazardous Substances under the CWA. None of the chemicals in this product are listed as Priority Pollutants under the CWA. None of the chemicals in this product are listed as Toxic Pollutants under the CWA. OSHA: None of the chemicals in this product are considered highly hazardous by OSHA. STATE CAS# 69-53-4 can be found on the following state right to know lists: New Jersey. California Prop 65 California No Significant Risk Level: None of the chemicals in this product are listed. European/International Regulations European Labeling in Accordance with EC Directives Hazard Symbols: XN Risk Phrases: R 36/37/38 Irritating to eyes, respiratory system and skin. R 42/43 May cause sensitization by inhalation and skin contact. Safety Phrases: S 26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S 36/37/39 Wear suitable protective clothing, gloves and eye/face pr otection. WGK (Water Danger/Protection) CAS# 69-53-4: No information available. Canada - DSL/NDSL CAS# 69-53-4 is listed on Canada's DSL List. Canada - WHMIS This product has a WHMIS classification of D2A, D2B. This product has been classified in accordance with the hazard criteria of the Controlled Products Regulations and the MSDS contains all of the information required by those regulations. Canadian Ingredient Disclosure List
MSDS Creation Date: 11/17/2005 Revision #1 Date: 11/17/2005 The information above is believed to be accurate and represents the best information currently available to us. However, we make no warranty of merchantability or any other warranty, express or implied, with respect to such information, and we assume no liability resulting from its use. Users should make their own investigations to determine the suitability of the information for their particular purposes. In no event shall Fisher be liable for any claims, losses, or damages of any third party or for lost profits or any special, indirect, incidental, consequential or exemplary damages, howsoever arising, even if Fisher has been advised of the possibility of such damages.
Vlaams Diergeneeskundig Tijdschrift, 2009, 78 Overzichtsartikel 239 Biggencastratie onder verdoving 1S. Van Beirendonck, 1,2B. Driessen, 2R. Geers 1Katholieke Hogeschool Kempen, Cluster Dier&Welzijn, Kleinhoefstraat 4, B-2440 Geel2Zoötechnisch Centrum, K.U.Leuven, Bijzondere weg 12, B-3360 Lovenjoel SAMENVATTING De castratie van biggen staat bekend als een belangrijk economisch
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