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Should Diet Pill Go Over The Counter?
whether there would be any lasting benefit
"There is no magic pill for weight loss and
counter sales of a weight-loss pill now sold
orlistat is not a magic pill. Orlistat is a tool
that will help people control their calorie
intake and modify their diet," said John
GlaxoSmithKline Consumer Healthcare seeks
Dent, the pharmaceutical company's senior
to sell a nonprescription version of orlistat, a
vice president of research and development.
drug marketed as Xenical, that overweight
adults could use as a weight-loss aid. The
bag contents are subject to change based on availability.
Public Citizen urged the panel to reject the
prescription version of the fat -blocking pill
"desperate attempt to revive this barely
A joint FDA advisory committee was to vote
on whether to recommend approval late Mon-
Deborah Fisher, a nurse from the Baltimore
day. The agency usually follows the recom-
area, told the panel: "We need this new
mendations of its outside panels of experts.
solution to losing weight and keeping it
nonprescription weight-loss drugs for sale.
"Eat less, move more: It sounds pretty sim-
In six-month clinical trials, obese people who
ple, doesn't it? Well, as my kids say, not!"
took orlistat lost on average 5.3 pounds to 6.2
said Fisher, adding that she's dieted for 45
pounds more than did those who were given
dummy pills. Glaxo wants people to use it for
only six months at a time, but as an over-the-
The proposed over-the-counter orlistat pill,
counter item, its use could not be policed.
called Alli (pronounced "ally"), would con-
tain half the dose of the prescription cap-
However, the pill's effect ends once its use is
stopped, said Dr. Julie Golden, a medical
officer in the FDA's division of metabolism
week, Glaxo said. The company estimated 5
study showed a progressive weight gain in
million to 6 million Americans a year would
the items we’ve ordered, which makes it difficult for us to fulfill
patients after they discontinued use of orl-
buy the drug if offered over the counter.
"I am concerned that this, while in the short
term may be useful, in the long term it may
not be," said FDA panel member Dr. Neal
tioned whether consumers would be able to
distinguish Alli from non-approved dietary
supplements also sold as weight-loss aids.
Glaxo said the drug helps the overweight slim
They also expressed concern about its effect
exercise regimen. The drug's actual effect on
on vitamin intake. Half of the patients en-
weight loss is "gradual and modest," said
rolled in trials of the drug failed to under-
rectly stated that the drug was inappropriate for them, according to
stand labeling directions that they should take supplemental vita-
mins at least two hours before or after using the pills.
Those results worried FDA reviewers, who questioned the risk of
The drug also could cause problems for organ transplant patients
selling the drug directly to consumers "without the principal in-
taking the drug cyclosporine as well as those on warfarin, a blood
volvement of a learned intermediary," or prescribing doctor.
thinner. The drug's label would warn such patients against taking
The reviewers also expressed concern about the increased potential
for abuse or misuse of a prescription-free version of the drug, es-
When taken with meals, orlistat blocks the absorption of about
pecially among bulimics or binge-eaters who could develop vita-
one-quarter of any fat consumed. That fat -- the equivalent of
about 150 to 200 calories -- is passed out of the body in stools,
which can be loose or oily as a result. Other side effects include
The company said there was a "very low" potential for abuse, with
gas, incontinence and oily spotting. About half of patients in trials
only four published reports of bulimics using the drug. More than
experienced such side effects, the company said.
22 million people worldwide have used orlistat in prescription
Furthermore, just 35 percent of diabetes patients in a study cor-
Swiss Chard with Carrots
In a food processor bowl, combine croutons, black pepper, cayenne
pepper, chili powder, and thyme. Pulse until the mixture is of a fine
texture. Place this mixture into a large bowl. Combine the onion, carrot,
garlic, and red pepper in the food processor bowl. Pulse until the mix-
ture is finely chopped, but not pureed. Combine the vegetable mixture,
ground sirloin, and ground chuck with the bread crumb mixture. Season
the meat mixture with the kosher salt. Add the egg and combine thor-
Pack this mixture into a 10-inch loaf pan to mold the shape of the meat-
Warm olive oil in the pan, with chilli and garlic; before the garlic
loaf. Onto a parchment paper-lined baking sheet, turn the meatloaf out
browns remove from heat and take out the garlic. Wash chard, separate
of the pan onto the center of the tray. Insert a temperature probe at a 45
leaves from the stems and then cut the leaves into large pieces. Peel
degree angle into the top of the meatloaf. Avoid touching the bottom of
carrots, slice thinly on the diagonal, then into narrow strips.
the tray with the probe. Set the probe for 155 degrees.
In a large pan of boiling water, briefly cook chard stems and carrots
Combine the ketchup, cumin, Worcestershire sauce, hot pepper sauce
until tender. Cook the chard leaves quickly in water and drain in a col-
and honey. Brush the glaze onto the meatloaf after it has been cooking
ander and then press the leaves with a wooden spoon to remove excess
water. Mix all the vegetables together and season with salt and pepper.
Dress with the chili and garlic oil. This can be served hot or at room
temperature with the optional splash of vinegar or lemon juice
Garden Vegetable Soup
Alton's Meat Loaf
• 2 cups chopped leeks, white part only
• 2 carrots, peeled and chopped into rounds
• 2 cups fresh green beans, broken or cut into 3/4 -inch pieces
• 4 cups peeled, seeded, and chopped tomatoes
• 1/4 cup packed, chopped fresh parsley leaves
Heat the olive oil in large, heavy-bottomed stockpot over medium-low
heat. Once hot, add the leeks, garlic, and a pinch of salt and sweat until
they begin to soften, approximately 7 to 8 minutes. Add the carrots,
potatoes, and green beans and continue to cook for 4 to 5 more minutes,
Add the stock, increase the heat to high, and bring to a simmer. Once
simmering, add the tomatoes, corn kernels, and pepper. Reduce the heat
to low, cover, and cook until the vegetables are fork tender, approxi-
mately 25 to 30 minutes. Remove from heat and add the parsley and lemon juice. Season, to taste, with kosher salt. Serve immediately.
SCOTIA-GLENVILLE CENTRAL SCHOOL DISTRICT DISTRICT OFFICE Regular Meeting of the Board of Education Monday, May 13, 2013 6:00 PM – Audit Committee Meeting 7:00 PM - Open Session Library Media Center Middle School Scotia-Glenville Mission Statement The Scotia-Glenville Central School District is committed to providing an environment which allows students to realize
El doctor A. Fernández Cruz, Catedrático y Jefe del Servicio de Medicina Interna del Hospital Clínico San Carlos de Madrid, participa el próximo 9 y 10 de mayo en una reunión internacional sobre óxido nítrico que organizan la Sociedad Española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA) y Área Científica Menarini en Barcelona. La princi