Microsoft word - porter

Virginia Commonwealth University
Department of Psychology
Joseph H. Porter
Professor and Director of Biopsychology Program
Affiliate Professor in the Departments of Pharmacology & Toxicology and Biology
Education
Ph.D. (1974), University of Georgia
Program affiliation
Biopsychology
Book
Porter, J. H., & Hamm, R. J. (1986) Statistics: Applications for the behavioral sciences.
Brooks/Cole Publishing Company. (Out of Print)
Book Chapter
Porter, J. H. (2011). Discriminative stimulus properties of receptor antagonists. In R. A.
Glennon & R. Young (Eds.), Drug discrimination: Applications to medicinal chemistry and drug studies. Hoboken, NJ: John Wiley & Sons.
Journal Articles

Wiebelhaus, J. M., Vunck, S. A., Meltzer, H. Y., & Porter, J. H. (in press).
Discriminative stimulus properties of N-desmethylclozapine, the major active metabolite of the atypical antipsychotic clozapine in C57BL/6 mice. Behavioural Pharmacology. Wiebelhaus, J. M., Webster, K. A., Meltzer, H. Y., & Porter, J. H. (2011). The metabolites N-desmethylclozapine and N-desmethylolanzapine produce cross-tolerance to the discriminative stimulus of the atypical antipsychotic clozapine in C57BL/6 mice. Behavioural Pharmacology, 22, 458–467. Vunck, S. A., Wiebelhaus, J. M., Arnt, J., & Porter, J. H. (2011). Clozapine and N- Methyl-D-Aspartate have positive modulatory actions on their respective discriminative stimulus properties in C57BL/6 mice. European Journal of Pharmacology, 650, 579–585. Porter, J. H., & Prus, A. J. (2009). Drug discrimination: 30 years of progress. Psychopharmacology, 203, 189–191. Vann, R. E., Wise, L. E., Varvel, S. A., Philibin, S. D., Walentiny, D. M., & Porter, J. H. (2009). Route of administration influences substitution patterns in rats trained to discriminate methadone vs. vehicle. Drug and Alcohol Dependence, 103, 124-130. Porter, J. H., & Prus, A. J. (2009). Discriminative stimulus properties of atypical and typical antipsychotic drugs: A review of preclinical studies. Psychopharmacology 203, 279–294. (REVIEW ARTICLE) Philibin, S. D., Walentiny, D. M., Vunck, S. A., Prus, A. J., Meltzer, H. Y., & Porter, J. H. (2009). Further characterization of the discriminative stimulus properties of the
atypical antipsychotic drug clozapine in C57BL/6 mice and a comparison to
clozapine’s major metabolite N-Desmethylclozapine. Psychopharmacology, 203,
303–315.
Prus A. J., Pehrson A. L., Philibin S. D., Wood J. T., Vunck S. A., Porter J. H. (2009). The role of M1 muscarinic cholinergic receptors in the discriminative stimulus properties of N-desmethylclozapine and the atypical antipsychotic drug clozapine in rats. Psychopharmacology, 203, 295–301. Porter J. H., Walentiny D. M., Philibin S. D., Vunck S. A., & Crabbe J. C. (2008). A comparison of the discriminative stimulus properties of the atypical antipsychotic drug clozapine in DBA/2 and C57BL/6 inbred mice. Behavioural Pharmacology, 19, 530–542. Lieberman J.A., Bymaster F.P., Meltzer H.Y., Deutch A.Y., Duncan G.E., Marx C.E., Aprille J.R., Dwyer D.S., Li X.-M., Mahadik S.P., Duman R.S., & Porter J.H.,
Modica-Napolitano J.S., Newton S.S., Csernansky J.G. (2008). Antipsychotic
drugs: Comparison in animal models of efficacy, neurotransmitter regulation, and
neuroprotection. Pharmacological Reviews, 60, 358–403. (REVIEW
ARTICLE)
Prus A.J., Philibin S.D., Pehrson A.L., & Porter J.H. (2006). The discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle in a three-choice drug discrimination task. Behavioural Pharmacology, 17, 185-194. Prus A.J., Philibin S.D., Pehrson A.L., Cooper R.N., & Porter J.H. (2005). Generalization to atypical antipsychotic drugs depends on training dose in rats trained to discriminate 1.25 mg/kg clozapine versus 5.0 mg/kg clozapine versus vehicle in a three-choice drug discrimination task. Behavioural Pharmacology, 16, 511-520. Philibin S.D., Prus A.J., Pehrson A.L., and Porter J.H. (2005) Serotonin receptor mechanisms mediate the discriminative stimulus properties of the atypical antipsychotic clozapine in C57BL/6 mice. Psychopharmacology, 180, 49-56. Prus A.J., Philibin S.D., Pehrson A.L., Stephens C.L., Cooper R.N., Wise L.E., and Porter J.H. (2005). Generalization testing with atypical and typical antipsychotic drugs in rats trained to discriminate 5.0 mg/kg clozapine from vehicle in a two-choice drug discrimination task. Drug Development Research, 64, 55-66. Porter J.H., Prus A.J., Varvel S.A., and Vann R.E. (2005). Discriminative stimulus properties of the atypical antipsychotic clozapine and the typical antipsychotic chlorpromazine in a three-choice drug discrimination procedure in rats. Psychopharmacology, 178, 67-77 (Published Online, 2004, DOI: 10.1007/s00213-004-1985-5) Varvel, S.A., Vann, R.E., Wise, L.E., Philibin, S.D., and Porter, J.H. (2002) Effects of antipsychotic drugs on operant responding after acute and repeated administration Psychopharmacology, 160, 182-191 Porter, J.H., Varvel, S.A., Vann, R.E., Philibin, S.D., and Wise, L.E. (2000) Clozapine discrimination with a low training dose distinguishes atypical from typical antipsychotic drugs in rats. Psychopharmacology, 149, 189-193 Porter, J.H., McCallum, S.E., Varvel, S.A., and Vann, R.E. (2000) The discriminative stimulus properties of the atypical antipsychotic olanzapine in rats. Psychopharmacology, 148, 224-233 Porter, J.H., Covington, III, H.E., Varvel, S.E., Vann, R.E., and Warren, T.A. (1999) Chlorpromazine as a discriminative stimulus in rats: generalization to typical and atypical antipsychotics. Drug Development Research, 48, 38-44 Porter, J.H., Villanueva, H.F., and Rosecrans, J.A. (1999) The role of D1 and D2 dopamine receptors in the discriminative stimulus properties of the atypical antipsychotic clozapine in rats. Drug Development Research, 46, 139-147 Wiley, J.L., Compton, A.D., Holcomb, J.D., McCallum, S.E., Varvel, S.A., Porter, J.H., and Balster, R.L. (1998) Effects of modulation of NMDA neurotransmission on response rate and duration in a conflict procedure in rats. Neuropharmacology, 37, 1527-1534 Kelley, B.M. and Porter, J.H. (1997) The role of muscarinic cholinergic receptors in the discriminative stimulus properties of clozapine in rats. Pharmacology, Biochemistry & Behavior, 57, 707-719 Porter, J.H. and Strong, S.E. (1996) Discriminative stimulus control with olanzapine: generalization to the atypical antipsychotic clozapine. Psychopharmacology, 128, 216-219 Kelley, B.M., Porter, J.H., and Varvel, S.A. (1995) Mianserin as a discriminative stimulus in rats: asymmetrical cross-generalization with scopolamine. Psychopharmacology, 120, 491-493 Porter, J.H., Heath, G.F., and Rosecrans, J.A. (1994) Antagonism of diazepam's anticonflict effects in rats by nicotine, but not by arecoline. Drug Development Research, 31, 45-51 Wiley, J.L., Compton, A.D., and Porter, J.H. (1994) Differential effects of clozapine and pimozide on fixed ratio responding during repeated dosing. Pharmacology, Biochemistry & Behavior, 48, 253-257 Wiley, J.L., Compton, A.D., and Porter, J.H. (1993) Effects of four antipsychotics on punished responding in rats. Pharmacology, Biochemistry & Behavior, 45, 263-267 Wiley, J.L. and Porter, J.H. (1993) Effects of serotonergic drugs in rats trained to discriminate clozapine from haloperidol. Bulletin of the Psychonomic Society, 31, 94-96 Villanueva, H.F. and Porter, J.H. (1993) Differential tolerance to the behavioral effects of chronic pimozide and clozapine on multiple random interval responding in rats. Behavioural Pharmacology, 4, 201-208 Wiley, J.L., and Porter, J.H. (1992) Serotonergic drugs do not substitute for clozapine in clozapine-trained rats in a two-lever drug discrimination procedure. Pharmacology, Biochemistry & Behavior, 43, 961-965 Wiley, J.L., Porter, J.H., Compton, A.D., and Balster, R.L. (1992) Antipunishment effects of acute and repeated administration of phencyclidine and NPC 12626 in rats. Life Sciences, 50, 1519-1528 Lambert, K.G., and Porter, J.H. (1992) Pimozide mitigates excessive running in the activity-stress paradigm. Physiology and Behavior, 52, 299-304 Wiley, J.L. and Porter, J.H. (1990) Differential effects of haloperidol and clozapine on the reinforcing efficacy of food reward in an alleyway reacquisition paradigm. Pharmacology Biochemistry & Behavior, 36, 569-573 Porter, J.H., Wiley, J.L., and Balster, R.L. (1989) Effects of phencyclidine-like drugs on punished behavior in rats. Journal of Pharmacology and Experimental Therapeutics, 248, 997-1002 Wiley, J.L., Porter, J.H., and Faw, W.R. (1989) Haloperidol blocks reacquisition of operant running during extinction following a single priming trial with food reward. Bulletin of the Psychonomic Society, 27, 340-342 Porter, J.H., and Villanueva, H.F. (1988) Assessment of pimozide's motor and hedonic effects on operant behavior in rats. Pharmacology Biochemistry & Behavior, 31, 779-786 Jeter, C.R., Bush, J.P., and Porter, J.H. (1988) Situational anxiety and blood pressure lability in the physician's office. Clinical and Experimental Hypertension, 10, 169-185 O'Neal, M.F., Means, L.W., Porter, J.H., Rosecrans, J.A., and Mokler, D.J. (1988) Rats that acquire a THC discrimination more rapidly are more sensitive to THC and faster in reaching operant criteria. Pharmacology, Biochemistry & Behavior, 29, 67-71 Kaempf, G.L. and Porter, J.H. (1987) Differential effects of pimozide and clozapine on schedule-controlled and schedule-induced behavior after acute and chronic administration. Journal of Pharmacology and Experimental Therapeutics, 243, 437-445 Messmer, J.M., Porter, J.H., Fatouros, P., Prosad, U., and Weisberg, M. (1987) Exposure to magnetic imaging does not produce taste aversion in rats. Physiology and Behavior, 40, 259-261 Murphy, E.P., Porter, J.H., and Heath, G.F. (1985) Suppression of schedule-induced drinking and food-reinforced barpressing by tail-pinch is not reversed by naloxone. Behavioral and Neural Biology, 43, 86-99 Porter, J.H. (1985) Schedule-induced polydipsia: Another look at water-intake volume regulation. Physiology and Behavior, 35, 221-227 Lynch, M.R. and Porter, J.H. (1985) Failure to block opiate effects of oral etonitazene with naltrexone during 24-hr choice testing. Bulletin of the Psychonomic Society, 23, 141-144 McDonough, J.J., Porter, J.H., and Heath, G.F. (1985) Effects of glucose-saccharin preloads on schedule-induced and deprivation-induced drinking in rats. Behavioral and Neural Biology, 23, 759-763 DeNoble, V.J., Mele, P.C., and Porter, J.H. (1985) Intravenous self-administration of pentobarbital and ethanol in rats. Pharmacology Biochemistry & Behavior, 23, 759-763 Porter, J.H., Goldsmith, P.A., McDonough, J.J., Heath, G.F., and Johnson, D.N. (1984) Differential effects of dopamine blockers on the acquisition of schedule-induced drinking and deprivation-induced drinking. Physiological Psychology, 12, 302-306 Lynch, M.R., Porter, J.H., and Rosecrans, J.A. (1984) Latent inhibition in the aversion to oral methadone. Pharmacology, Biochemistry & Behavior, 20, 467-472 Rappold, V A., Porter, J.H., and Llewellyn, G.C. (1984) Evaluation of the toxic effects of aflatoxin B1 with a taste aversion paradigm in rats. Neurobehavioral Toxicology and Teratology, 6, 51-58 Granger, R.G., Porter, J.H., and Christoph, N.L. (1984) Schedule-induced behavior in children as a function of inter-reinforcement interval length. Physiology and Behavior, 33, 153-157 Porter, J.H. and Hamm, R.J. (1984) Associative control of schedule-induced drinking. Animal Learning and Behavior, 12, 339-340 Porter, J. H. (1983) Schedule-induced polydipsia as a function of percent of body weight in the Mongolian gerbil. Physiology and Behavior, 31, 137-139 McDonough, J.J. and Porter, J.H. (1983) Schedule-induced and water-deprivation- induced drinking in rats: Effects of hypertonic saline challenges to homeostatic thirst mechanisms. Bulletin of the Psychonomic Society, 21, 403-406 Bryant, W.E., Jr. and Porter, J.H. (1983) A comparison of schedule-induced wheel running in rats, hamsters, gerbils, and guinea pigs. Bulletin of the Psychonomic Society, 21, 311-314 Lynch, M.R., Porter, J.H., and Rosecrans, J.A. (1982) Schedule-induced vs. home cage ethanol consumption: Influence of food deprivation. Bulletin of the Psychonomic Society, 19, 45-47 Porter, J.H., Brown, R.T., and Goldsmith, P.A. (1982) Adjunctive behavior in children on fixed interval reinforcement schedules. Physiology and Behavior, 28, 609-612 Porter, J.H., Hornbuckle, P.A., Lynch, M.R., and Crutchfield, D.V. (1982) The effects of bilateral and unilateral neocortical lesions on schedule-induced polydipsia in rats. Physiology and Behavior, 29, 177-181 Porter, J.H., McDonough, J.J., and Young, R. (1982) Intraperitoneal preloads of water, but not isotonic saline, suppress schedule-induced polydipsia in rats. Physiology and Behavior, 29, 795-801 Hamm, R.J., Porter, J.H., and Kaempf, G.L. (1981) Stimulus generalization of schedule- induced polydipsia. Journal of the Experimental Analysis of Behavior, 36, 93-99 McDonough, J.J., Porter, J.H., Goldsmith, P.A., and Granger, R.G. (1981) Schedule- induced polydipsia in F1 hybrid rats of wild-caught and domestic Norway rats. Physiology and Behavior, 26, 1001-1005 Rappold, V.A., Hicks, M.A., Kinzie, J.M., Llewellyn, G.C., and Porter, J.H. (1981) The effects of the hepatocarcinogen, aflatoxin, on photocell activity in rats. IRCS Medical Science: Cancer, 9, 463-464 Porter, J.H., Johnson, S.B., and Granger, R.G. (1981) The Snark is still a Boojum. Comparative Psychology Newsletter, l (No. 5), 1-3 Porter, J.H., Hasting, M.T., Jr., and Pagels, J.F. (1980) Schedule-induced polydipsia in the cotton rat (Sigmodon hispidus). Bulletin of the Psychonomic Society, 16, 15-18 Young, R. and Porter, J.H. (1979) Effects of body weight and level of deprivation on activity of rats with lesions of the ventromedial hypothalamus. Physiological Psychology, 7, 178-184 Fisher, R.B. and Porter, J.H. (1979) Failure to demonstrate schedule-induced polydipsia in the Degu (Octodon degus). Psychological Reports, 44, 1276 Porter, J.H. and Bryant, W.E., Jr. (1978) Adjunctive behavior in the Mongolian gerbil. Physiology and Behavior, 21, 151-155. Hamm, R.J., Porter, J.H., and Oster, G.D. (1978) Compound stimulus control of operant, but not adjunctive behavior. Bulletin of the Psychonomic Society, 12, 167-170 Porter, J.H., Young, R., and Moeschl, T.P. (1978) Effects of water and saline preloads on schedule-induced polydipsia in the rat. Physiology and Behavior, 21, 333-338 Porter, J.H. and Bryant, W.E., Jr. (1978) Acquisition of schedule-induced polydipsia in the Mongolian gerbil. Physiology and Behavior, 21, 825-837 Young, R., Porter, J.H., Morgan, J.D., and Llewellyn, G.C. (1978) Effects of the hepatocarcinogen, aflatoxin, on open-field behaviors in Syrian hamsters. Behavioral Biology, 23, 536-542 Porter, J.H. and Allen, J.D. (1977) Food-motivated performance in rats with ventromedial hypothalamic lesions: Effects of body weight, deprivation, and preoperative training. Behavioral Biology, 19, 238-254 Porter, J.H. and Allen, J.D. (1977) Schedule-induced polydipsia contrast in the rat. Animal Learning and Behavior, 5, 184-192 Allen, J.D. and Porter, J.H. (1977) Sources of control over schedule-induced drinking produced by second-order schedules of reinforcement. Physiology and Behavior, 18, 853-863 Porter, J.H., Sozer, N.N., and Moeschl, T.P. (1977) Schedule-induced polydipsia in the guinea pig. Physiology and Behavior, 19, 573-575 Roehrs, T., Allen, J.D., and Porter, J.H. (1976) Acquisition of schedule-induced polydipsia in rats with no prior drinking experience. Physiology and Behavior, 17, 1011-1013 Porter, J.H., Arazie, R., Holbrook, J.W., Cheek, M.S., and Allen, J.D. (1975) Effects of variable and fixed second-order schedules in schedule-induced polydipsia in the rat. Physiology and Behavior, 14, 143-149 Allen, J.D., Porter, J.H., and Arazie, R. (1975) Schedule-induced drinking as a function of percentage reinforcement. Journal of the Experimental Analysis of Behavior, 23, 223-232 Porter, J.H. (1975). MAP-FT Project Evaluation Report: Gulfport, Mississippi. Athens, Georgia: University of Georgia, Mathemagenic Activities Program Follow-Through, and June. (Technical Report) Allen, J.D. and Porter, J.H. (1975) Demonstration of behavioral contrast with adjunctive drinking. Physiology and Behavior, 15, 511-515 Porter, J.H. and Kenshalo, D.R., Jr. (1974) Schedule-induced drinking following omission of reinforcement in the rhesus monkey. Physiology and Behavior, 12, 1075-1077 Porter, J.H., Allen, J.D., and Arazie, R. (1974) Reinforcement frequency and body weight as determinants of motivated performance in hyperphagic rats. Physiology and Behavior, 13, 30627-632 Porter, J.H. and Tomasello, M. (1974) Post Follow Through - A preliminary evaluation of the usefulness of Stanford Achievement Tests in assessing the effects of Follow Through intervention. Athens, Georgia: University of Georgia, Mathemagenic Activities Program - Follow Through, December. (Technical Report) Porter, J.H. and Allen, J.D. (1972) Food-motivated performance as a function of weight loss in hypothalamic hyperphagic rats. Psychonomic Science, 28, 285-288

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