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Microsoft word - publications_abstracts.doc
Stern Consult Dr. Angelika C. Stern International clinical research consulting PUBLICATIONS
Stern, A.C., Erb, P., and R.H. Gisler. Ia-bearing bone marrow-cultured
macrophages induce antigen-specific helper T cells for antibody synthesis. J. Immunol. 123: 612, 1979.
Erb, P., Feldmann, M., Gisler, R.H., Meier, B., Stern, A.C., and P. Vogt. Role of
macrophages in the in vitro induction and regulation of antibody response. In 'Mononuclear Phagocytes'. Functional Aspects. R. van Furth (Ed.) Martinus Nijhoff, The Hague, 1980.
Erb, P., Stern, A.C., Alkan, S.S., Studer, S., Zoumbou, E., and R.H. Gisler.
Characterization of accessory cells required for helper T cell induction in vitro: Evidence for a phagocytic, Fc-receptor and Ia-bearing cell type. J. Immunol. 125:
2504, 1980. Stern, A.C. Structural and functional differentiation of murine macrophages from bone marrow stem cells in culture. Ph.D. thesis, Basel University, 1980. Gisler, R.H., Stern, A.C., Alkan, S.S., and P. Erb. Characterization of bone marrow-derived macrophages for T helper cell induction in vitro. In 'Heterogeneity of
Mononuclear Phagocytes'. O. Förster and M. Landy (Eds.) Academic Press, New York, p 201, 1981.
Erb, P., Stern, A.C., and M.J. Cecka. Ia determinants on macrophages: Significance
and role in the immune response. In 'Macrophage and Natural Killer Cells: Regulation and Function. S.J. Normann and E. Sorkin (Eds.) Plenum Press 1982. Erb, P., Ramila, G., Stern, A.C., and I. Sklenar. Role of macrophages in T cell activation. Proceedings of the 5th European Immunology Meeting, 1982.
Stern, A.C., Erb, P., McKenzie, I.F.C., and R.H. Gisler. Differentiation markers and
accessory function of murine macrophages from cultured bone marrow stem cells. Immunobiology 164: 63, 1983.
Brun del Re, G., Baumgartner, C., Stern, A.C., Hirt, A., Carrel, S. In vitro Behandlung von menschlichem Knochenmark zur Elimination von Turmorzellen:
Erste Erfahrungen mit dem zytotoxischen monoklonalen Anti-T-Zellantikörper LAU-A1. Schweiz. med. Wschr. 114: 1379-1382, 1984.
Baumgartner, C., Brun del Re, G.P., Forster, H.K., Bucher, U., Delaleu, B., Hirt, A.,
Imbach, P., Lüthy, A., Stern, A.C., Wagner, H.P. Autologous bone marrow transplantation for pediatric non-Hodgkin's lymphoma. In vitro purging of the graft
with anti-Y 29/55 monoclonal antibody and complement. In: Dicke, K.A., Spitzer, G., Zander, A.R., Gorin, N.C. (Eds.): "Autologous Bone Marrow Transplantation". Proceedings of the first international symposium. The University of Texas, M.D.
Anderson Hospital and Tumor Institute, Houston, pp. 377-381, 1985. Baumgartner, C., Brun del Re, G.P., Bleher, E.A., Bucher, U., Delaleu, B., Greiner, R., Hirt, A., Lüthy, A., Stern, A.C., Tschopp, L., Wagner, H.P. Autologe
Knochenmarks-Transplantation-Klinische Erfahrungen in Bern. Tagung der Schweizerischen Gesellschaft für Hämatologie, Interlaken, 09./10. Mai 1985.
Schweiz. med. Wschr., 115: 1519-1520, 1985.
Stern Consult Dr. Angelika C. Stern International clinical research consulting
Gerhartz, H. H., H. Schmetzer, B. Wolf-Hornung, A. C. Stern, W. Wilmans, Placebo-
controlled double blind study of granulocyte/macrophage colony-stimulating factor in chemotherapy-induced leukopenia, Bone Marrow Transplantation, Vol. 4, 105,
1989. Gerhartz, H., G. Visani, A. Delmer, H. Zwierzina, M. Ribeiro, A. Jacobs, R. Marcus, M. Baumelou, D. Fière, L. Labar, W. Sizoo, A. Efira, M. Peetermans, A.C. Stern, G.
Solub, S. Suicu, T. de Witte, R. Zittoun, Low dose ARA-C plus granulocyte-macrophage colony stimulating factor for the treatment of myelodysplastic
syndromes with excess of blasts, Bone Marrow Transplantation, 4, Suppl. 3, pp 36-37, 1989. Gianni, A. M., M. Bregni, A. C. Stern, G. Bonadonna, S. Siena, C. Tarella, A. Pileri, Granulocyte-macrophage colony-stimulating factor to harvest circulating
haemopoietic stem cells for autotransplantation, The Lancet, 580-584, 1989. Hazenberg, B.P.C, M.A. van Leeuwen, M.H. van Rijswijk, A.C. Stern, E. Vellenga, Correction of granulocytopenia in Felty's Syndrome by granulocyte-macrophage
colony-stimulating factor. Simultaneous induction of interleukin-6 release and flare-up of the arthritis. Blood, Vol. 74, pp 2269-2270, 1989. Kim, S., A. Gratwohl, C. Stebler, M. Hausmann, A. Tichelli, A.C. Stern, B. Speck, Accidental overdose of multiple chemotherapeutic agents, The Korean Journal of
Internal Medicine, 4, (2), pp 171-173, 1989. Thomssen, C., C. Nissen, A. Gratwohl, A. Tichelli, A.C. Stern, Agranulocytosis associated with T-gamma-lymphocytosis no improvement of peripheral blood
granulocyte count with human-recombinant granulocyte-macrophage-colony stimulating factor (GM-CSF). Brit J Haem 71, (1), pp 157-158, 1989. Aglietta M., W. Piacibello, A. C. Stern, F. Gavosto, Human granulocyte-macrophage colony stimulating factor: target cells and kinetics of response, Progress in Clinical
and Biological Research, Vol 352, New York, Wiley-Liss, pp 519-530, 1990. Aglietta, M., C. Monzeglio, W. Piacibello, F. Apra, A. Stacchini, F. Sanavio, C. Mossetti, A.C. Stern, F. Gavosto, GM-CSF: Intravenous versus subcutaneous
treatment, Leukemia, 4, 523, 1990. Aglietta, M., C. Monzeglio, F. Apra, C. Mossetti, A.C. Stern, G. Giribaldi, F.
Bussolino, In vivo priming of human normal neutrophils by granulocyte-macrophage colony stimulating factor: effect on the production of platelet
activation factor, British J of Hematology, 75, 333-339, 1990. Aglietta, M., W. Piacibello, A.C. Stern, F. Gavosto, Human granulocyt-macrophage colony stimulating factor: target cells and kinetics of response, Prog. Clin. Biol. Res.
352, pp 519-530 , 1990. Biesma, B., E. De Vries, P. Willemse, W. Sluiter, P. Postmus, P. Limburg, E.
Vellenga, A.C. Stern, Efficacy and tolerability of recombinant human granulocyte -macrophage colony stimulating factor in patients with chemotherapy related
leukopenia and fever, Eur J Cancer, Vol. 26, No. 9, pp 932-936, 1990. Gianni, A.M., M. Bregni, S. Siena, A. Orazi, A.C. Stern, L. Gandola, G. Bonadonna, Recombinant human granulocyte-macrophage colony-stimulating factor reduces
hematologic toxicity and widens clinical applicability of high-dose cyclophosphamide
Stern Consult Dr. Angelika C. Stern International clinical research consulting
treatment in breast cancer and non-Hodgkin's lymphoma, J. Clin. Oncol 8, pp 768-
778, 1990. Piacibello, W., C. Camaschella, A.C. Stern, M. Aglietta, Granulocyte macrophage colony stimulating factor (GM-CSF) reduces pancytopenia after rescue therapy in a
patient with Hodgkin's lymphoma. Leuk. Lymphoma, Vol 3, pp 61-66, 1990. Stern, A.C., Jones, T.C., Role of human recombinant GM-CSF in the prevention and treatment of leukopenia with special reference to infectious diseases, Diagn
Microbiol Infect Dis, 13, pp 391-396, 1990. Aglietta, M., C. Monzeglio, F. Sanavio, F. Apra, S. Morelli, A. Stacchini, W.
Piacibello, F. Bussolino, G. Bagnara, G. Zauli, A.C. Stern, F. Gavosto, In vivo effect of human granulocyte-macrophage colony-stimulating factor on
megakaryocytopoiesis, Blood, Vol. 7, No. 6, pp. 1991-1994, 1991. Aglietta, M., L. De Felice, A. Stacchini, M.C. Petti, A.C.M. Bianchi, M.A. Aloe Spiriti, F. Sanavio, F. Apra, W. Piacibello, A.C. Stern, F. Gavosto, F. Mandelli, In vivo effect
of granulocyte-macrophage colony-stimulating factor on kinetics of human acute myeloid leukemia cells, Leukemia, Vol. 5, No. 11, pp 979-984, 1991. Aulitzky, W.E., T.F. Schultz, H. Tilg, D. Niederwieser, K. Larcher, L. Oestberg, M. Scriba, J. Martindale, A.C. Stern, P. Grass, M. Mach, M.P. Dietrich, C. Huber,
Human monoclonal antibodies neutralizing cytomegalovirus (CMV) for prophylaxis of CMV disease: report of a phase I trial in bone marrow transplant recipients, The
Journal of Infectious Diseases, 163; 1344-1347, 1991. De Vries, E.G.E., B. Biesma, P.H.B. Willemse, N.H. Mulder, A.C. Stern, J.G. Aalders, E. Vellenga, A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcinoma, Cancer
Research 51, 116-122, 1991. De Vries, E.G.E., P.H.B. Willemse, B. Biesma, A.C. Stern, P.C. Limburg, E. Vellenga, Flare-up of rheumatoid arthritis during GM-CSF treatment after chemotherapy, The
Lancet, Vol. 338, pp 517-518, 1991. De Vries, E.G.E., P.H.B. Willemse, N.H. Mulder, A.C. Stern, J.G. Aalders, E. Vellenga, A double-blind placebo-controlled study with granulocyte-macrophage colony-stimulating factor during chemotherapy for ovarian carcioma, Cancer
Research, 51, 115-122, 1991. Gerhartz, H.H., R. Marcus, A. Delmer, H. Zwierzina, T. de Witte, A. Jacobs, G. Visani, D. Fiere, P. Sonnefeld, B. Labar, A.V. Hoffbrand, P. Fenaux, M. Hayat, A.
Thyss, L. Debucher, B. Coiffier, W. Sizoo, R. Willemze, M. Ribeiro, S. Succiu, G. Solbu, A.C. Stern, R. Zittoun for the EORTC Leukemia Group, Randomized phase II
study with GM-CSF and low-dose AraC in patients with 'high-risk' myelodysplastic syndromes (MDS), International Congress and Symposium Series, Breakthrough in Cytokine Therapy: An Overview of GM-CSF, Edited by J.H. Scarffe, pp. 27-40,
1991. De Witte, T., A. Gratwohl, N. Van Der Lely, P. Muus, A.C. Stern, B. Speck, C. Nissen, A. Marmont, A. Bacigalupo, E. Gluckman, U. Gugerli, F. Zwaan,
Recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF) in bone marrow transplantation (BMT), International Congress and
Symposium Series, Breakthrough in Cytokine Therapy: An Overview of GM-CSF, Edited by J.H. Scarffe, pp. 45-54, 1991.
Stern Consult Dr. Angelika C. Stern International clinical research consulting
Gerhartz, H.H., A.C. Stern, B. Wolf-Hornung, M. Kazempour, H. Schmetzer, M. Beykirch, U. Gugerli, W. Wilmanns, Treatment of neutropenia in patients
undergoing cancer chemotherapy, International Congress and Symposium Series, Breakthrough in Cytokine Therapy: An Overview of GM-CSF, Edited by J.H. Scarffe,
pp. 79-93, 1991. Stern, A.C., Jones, T.C., Use of human recombinant granulocyte-macrophage colony-stimulating factor (GM-CSF) in infectious diseases,International Congress
and Symposium Series, Breakthrough in Cytokine Therapy: An Overview of GM-CSF, Edited by J.H. Scarffe, pp 101-106, 1991. Aglietta M., Monzeglio C., Bussolino F., Piacibello W., Sanavio F., Stacchini A., Pasquino P., Valpreda S., Apra F., Fubini L, Morelli S., Severino A., Stern A.C.,
Gavosto F., Cell kinetics-based protocols: A possible new approach to the use of GM-CSF. International Congress and Symposium Series, Breakthrough in Cytokine
Therapy: An Overwiew of GM-CSF, Edited by J. H. Scarffe, pp 107-112. Gratwohl, A., H. Dazzi, A. Tichelli, Ch. Stebler, M. Wernli, Ch. Thomssen, I. Kim, A. Dieterle, R. Obrist, A.C. Stern, C. Nissen, B. Speck, Notfalltherapie mit Granulozyten-Macrophagen Stimulierendem Faktor (GM-CSF), Schweiz. med.
Wschr., 121: 413-417, 1991. Hollander, A.A.M.J., H.C. Kluin-Nelemans, H.R. Haak, A.C. Stern, R. Willemze, W.E. Fibbe, Correction of neutropenia associated with chronic lymphocytic leukaemia
following treatment with granulocyte-macrophage colony-stimulating factor, Annals of Hematology, 62: 1: 32-34, 1991.
Siena, S., M. Bregni, B. Brando, N. Belli, F. Ravagnani, L. Gandola, A.C. Stern, P.M. Lansdorp, G. Bonadonna, A.M. Gianni, Flow cytometry for clinical estimation of
circulating hematopoietic progenitors for autologous transplantation in cancer patients, Blood, 77, Nr. 2, 1991.
Barnas, C., H. Zwierzina, M. Hummer, B. Sperner-Unterweger, A.C. Stern, W.W.
Fleischhacker, Granulocyte-macrophage colony-stimulating factor (GM-CSF) treatment of clozapine-induced agranulocytosis: A case report. Journal of Clinical
Psychiatry, Vol. 53, pp 245-247, 1992. De Witte, T., A. Gratwohl, N. Van der Lely, A. Bacigalupo, B. Speck, T.
Schattenberg, C. Nissen, E. Gluckman, W.E. Fibbe, A.C. Stern, Recombinant human granulocyte-macrophage colony stimulating factor accelerates neutrophil
and monocyte recovery after allogeneic T-cell depleted bone marrow transplantation, Blood, Vol 79, No. 5, pp 1359-1365, 1992.
Gerhartz, H.H., R. Marcus, A. Delmer, H. Zwierzina, S. Suciu, M. Dardenne, G.
Solbu, T. de Witte, A. Jacobs, G. Visani, D. Fiere, P. Sonneveld, B. Labar, A.V.
Hoffbrand, P. Fenaux, M. Hayat, A. Thyss, L. Bebusscher, B. Coiffier, W. Sizoo, R.
Willemze, M. Ribeiro, F. Mandelli, G. Burghouts, C. Cauchie, M. Peetermans, K.J.
Roozendaal, R. Goudsmit, D. Douer, G.L. Castoldi, A.C. Stern, R. Zittoun,
Treatment of myedodysplastic syndrome (MDS) with a high risk of developing
leukemia with low-dose cytosine arabinoside (LD-AraC) plus
granulocyte/macrophage colony-stimulating factor (rh GM-CSF): A randomized
phase II study. Infection, Vol 20, Suppl. 2, pp 116-123, 1992.
Stern, A.C., Clinical Uses for GM-CSF. An International Symposium, Beijing, China,
Stern Consult Dr. Angelika C. Stern International clinical research consulting
Stern, A.C., Jones, T.C., The side effect profile of GM-CSF. Infection, Suppl. 2, pp
Willemze, R., N. van der Lely, H. Zwierzina, H. Gerhartz, B. Labar, G. Visani, M.E.
Peetermans, A. Jacobs, P. Stryckmans, P. Fenaux, H.L. Haak, M.M. Ribeiro, E.
Baumelou, M. Baccarani, F. Mandellik, B. Jaksic, A. Louwagie, A. Thyss, M. Hayat,
F. de Cataldo, A.C. Stern, S. Suciu, G. Solbu, R. Zittoun, A randomized phase I/II
multicenter study of recombinant human granulocyte-macrophage colony-
stimulating factor (GM-CSF) therapy for patients with myelodysplastic syndromes
and a relatively low risk of acute leukemia, Ann Hematol 64: pp 173-180, 1992.
Aglietta, M. C. Monzeglio, P. Pasquino, A.C. Stern, F. Gavosto, Short treatment with
GM-CSF prior to chemotherapy decreases hemopoietic toxicity of cytostatic agents.
Gerhartz, H.H., A.C. Stern, B. Wolf-Hornung, M. Kazempour, H. Schmetzer, U.
Gugerli, T.C. Jones, W. Wilmanns, Intervention treatment of established
neutropenia with human recombinant granulocyte-macrophage colony-stimulating
factor (rhGM-CSF) in patients undergoing cancer chemotherapy. Leukemia
Reseach, Vol. 17, No. 2, pp 175-185, 1993.
Gerhartz, H.H., M. Engelhard, M. Meusers, G. Brittinger, W. Wilmanns, G.
Schlimok, D. Mueller, D. Huhn, R. Musch, W. Siegert, D. Gerhartz, J.H. Hartlapp, E.
Thiel, H. Seibt-Jung, Ch. Huber, Ch. Peschl, K. Spann, B. Emmerich, D. Schadek,
M. Westerhausen, H.W. Pees, H. Radtke, K. Engert, E. Terhardt, J. Schick, T.
Binder, R. Fuchs, J. Hasford, R. Brandmeier, A.C. Stern, T.C. Jones, H.J. Ehrlich, H.
Stein, M. Parawesch, M. Tiemann, K. Lennert, Randomized double-blind placebo-
controlled phase III study of recombinant human granulocyte-macrophage colony-
stimulating factor (rhGM-CSF) as adjunct to induction treatment of high-grade
malignant non-Hodgkin's lymphomas. Blood, Vol. 82, No. 8, pp 2329-2339, 1993.
Stern, A.C., Jones, T.C., Clinical experience with E.coli rhGM-CSF. International
Review of Experimental Pathology, Vol. 34B, pp 209-216, 1993. Gerhartz HH, Marcus R, Delmer A et al. A randomized phase II study of low-dose cytosine arabinoside (LD-AraC) plus granulocyte-macrophage colony-stimulating
factor (rhGM-CSF) in myelodysplastic syndromes (MDS) with a high risk of developing leukemia. Leukemia, Vol. 8, No 1, pp 16-23, 1994. Stern A, Engelhardt R, Tschiersch A, Ehrlich H, Haus U, Foster C, Hildebrandt J, Mayer P, Golenbock D, Landmann R, Stütz P, SDZ MRL 953, A lipid A analog as
selective cytokine inducer. Proceedings of the 3rd Conference of the International Endotoxin Society, Helsinki, Finland, August 15-18, 1994.
Stern A, Engelhardt R, Foster C, Golenbock D, Hildebrandt J, Landmann R, Mayer
P, Stütz P, SDZ MRL 953, A lipid A analog as selective cytokine inducer. Bacterial Endotoxins, Lipopolysaccharides from Genes to Therapy, Progress in Clinical and Biological Research, Vol. 392, pp 549-565, 1995.
ABSTRACTS
Baumgartner, C., Brun del Re, G., Forster, H.K., Hirt, A., Imbach, P., Stern, A.C., Wagner, H.P. Autologous bone marrow transplantation for pediatric non-Hodgkin's
lymphoma: Factors influencing tumor control. Exp. Hematol. 12: 404, Abstract No. 124, 1984. Stern, A.C., Baumgartner, C., Brun del Re, G.P., Forster, H.K., Hirt, A., Morell, A., Wagner, H.P., Bucher, U. Purging of bone marrow with the B-lymphocyte specific
Stern Consult Dr. Angelika C. Stern International clinical research consulting
monoclonal antibody Y 29/55 and complement: Exclusion of antigenic modulation.
Annual Meeting of the EBMT, Bad Hofgastein, January 27-30, 1985. Exp. Hematol. (suppl. 17) 13: 53, 1985.
Brun del Re, G.P., Stern, A.C., Baumgartner, C., Knapp, W., Hirt, A., Morell, A.,
Bucher, U., Wagner, H.P. Purging of bone marrow with the monoclonal anti c ALLA antibodies VIL-AL, VIB-E3 and VIB-C5 as a prerequisit for autologous bone marrow
transplantation. Annual Meeting of the EBMT, Bad Hofgastein, January 27-30, 1985. Exp. Hematol. (suppl. 17), 13: 54, 1985.
Baumgartner, C., Bleher, E.A., Brun del Re, G., Frei, H., Greiner, R., Hirt, A., Imbach, P., Lüthy, A., Stern, A.C., Wagner, H.P. Long term effects of autologous
bone marrow transplantation performed in children with non-Hodgkin's lymphoma of B-cell type. Annual Meeting of the EBMT, Bad Hofgastein, January 27-30, 1985.
Exp. Hematol. (suppl. 17), 13: 27, 1985. Nissen, C., A.C. Stern, T.C. Jones, J. Schaedelin, European double blind randomized trial of GM-CSF in patients after transplantation of T-cell depleted bone
marrow. Abstract, Exp Hematol Vol. 16, No. 6, pp 235, 1988. Gianni, A. M., M. Bregni, A. C. Stern, S. Siena,C. Tarella, A. Orazi, G. Bonadonna,
Very rapid and complete hematopoietic reconstitution following combined transplantation of autologous bone marrow and GM-CSF-exposed stem cells, Bone
Marrow Transplantation, Vol. 4, 78, 1989. Philip, T., J. Michon, J.C. Gentet, J.L. Bernard, E. Bouffet, D. Frappaz, E. Quintana, C. Raybaud, M. Favrot, A.C. Stern, J.M. Zucker, Use of GM-CSF in the LMCE double
graft program for stage IV neuroblastoma: A double blind study on consecutive patients, abstract, 1989. Stoter, G., C.J.A. Punt, R.L.H. Jansen, R. Ruit, A.C. Stern, D. Batchelor, B. Loewenberg, GM-CSF is effective during repeated multiple cycles of
myelosuppressive chemotherapy, Proc. ASCO 8, (Abs. 737), 1989. De Witte, T., A. Gratwohl, N. Van Der Lely, P. Muus, A.C. Stern, T.C. Jones, J. Schaedelin, B. Speck, C. Nissen, A. Marmont, A. Bacigalupo, E. Gluckman, F.
Zwaan, A multicenter double blind randomised trial of recombinant human granulocyte-macrophage colony stimulating factor (GM-CSF) in recipients of allogeneic T-cell depleted bone marrow, abstract Nr. 40, Bone Marrow
Transplantation, 5, Suppl. 2, 1990. Gerhartz, H.H., A.C. Stern, B. Wolf-Hornung, Ghotbi, M. Goebel, W. Wilmanns, Use of granulocyte/macrophage colony-stimulating factor (GM-CSF) in patients treated
with antibiotics during neutropenia. Abstract, Exp. Hematolol. 18 (6), 599, 1990.
Gianni, A.M., S. Siena, M. Bregni, C. Tarella, D. Ferrero, F. Ravagnani, A.C. Stern, Factors influencing the yield of circulating haematopoietic progenitor cells harvested from cancer patients after high-dose cyclophosphamide treatment, with
or without rhGM-CSF infusion. 16th annual meeting of the EBMT. The Hague, The Netherlands, May 6-9, 1990.
Willemze, R., G. Visani, Th. de Witte, H. Zwierzina, B. Labar, A. Jacobs, H.
Gerhartz, H.L. Haak, A.C. Stern, S. Suciu, G. Solbu, R. Zittoun, A randomized
phase I/II dose finding study using recombinant human GM-CSF in patients (PTS)
with myelodysplastic syndromes at a relatively low risk of developing acute
leukemia, Blood Vol. 76 No. 10 Suppl. 1, abstract No. 1337, 1990.
Stern Consult Dr. Angelika C. Stern International clinical research consulting
Gianni, A.M., M. Bregni, S. Siena, C. Brambilla, F. Lombardi, L. Gandola, C. Tarella,
A. Stern, P. Valagussa, G. Bonadonna, Prospective randomized comparison of
MACOP-B vs. rhGM-CSF supported high-dose sequential myeloablative
chemotherapy in diffuse large cell lymphomas, ASCO, 1991.
Willemze, R., Th. de Witte, H. Zwierzina, B. Labar, G. Visani, H. Gerhartz, M.E.
Peetermans, A. Jacobs, F. Mandelli, A.C. Stern, S. Suciu, G. Solbu, R. Zittoun,
Prognostic factors with respect to response rate in patients (PTS) with
myelodysplastic syndromes (MDS) at a relatively low risk of developing acute
leukemia treated with recombinant human GM-CSF. Blood Vol. 78 No. 10 Suppl. 1,
Gerhartz, H.H., M. Engelhard, G. Brittinger, W. Wilmanns, D. Huhn, E. Thiel, C.
Huber, G. Schlimok, D. Gerhartz, B. Emmerich, K. Kabelitz, D. Schadek, H.W. Pees,
F. Deupmann, H. Schick, M. Schaefer, R. Brandmeier, S. Hasford, A.C. Stern, T.C.
Jones, Randomized double-blind placebo-controlled phase III study of recombinant
human granulocyte/macrophage colony stimulating factor (rhGM-CSF) as adjunct
to induction-treatment of agressive non-hodgkin lymohomas. Blood Vol. 80 No. 10
Engelhardt R, Foster C, Golenbock D, Hildebrandt J, Landmann R, Mayer P, Stern
A.C., Stütz P, SDZ MRL 953, a lipid A analog as selective cytokine inducer.
Abstract, Journal of Endotoxin Research, Vol 1, Supplement 1, pp 23, 1994.
Kiani A, Gaboriau E, Stern A.C., Seiz A, Hildebrandt D, Stütz P, Mertelsmann R,
Engelhardt R, The profile of endogenous cytokine release in response to SDZ MRL
953 is different compared to LPS (salmonella abortus equi). Abstract, Journal of
Endotoxin Research, Vol. 1, Supplement 1, pp 62, 1994.
Tschiersch A, Gaboriau E, Kiani A, Stern A.C., Hildebrandt J, Stütz P, Galanos C,
Mertelsmann R, Engelhardt R, Different patterns of cytokine production after
prestimulation with SDZ MRL 953 in response to LPS and bacterial lysate in cancer
patients. Abstract, Journal of Endotoxin Research, Vol 1, Supplement 1, pp. 92,
Kiani A, Gaboriau E, Haus U, Ehrlich H.J, Färber L, Stern A, Stütz P, Hildebrandt J,
Mertelsmann R, Engelhardt R, 21st Annual Meeting of the EBMT and 11th Meeting
of the Nurses Group, Davos, Switzerland, 1995.
Features MAY 2007 EDITION FIN 48 Revisited: Fog Clearing on Controversial Tax Disclosures View article examples as Redline | Comparison | Collapsed For months, issuers have stalled on the application of the Financial Accounting Services Board's Financial Interpretation Number 48 (FIN 48). Confounded by the complexity of FIN 48's evaluations, these issuers have sought reprie
Chapter 16 Solving Differential Equations This chapter describes how to solve both ordinary and partial differential equations having real-valued solutions. Mathcad Standard comes with the rkfixed function, a general-purpose Runge-Kutta solver that can be used on n th order differential equations with initial conditions or on systems of differential equations. Mathcad Professional includes a