Bc portfolio of papers

Portfolio of papers that highlight how chemical exposures may be implicated in breast
cancer

The Portfolio is a selection of peer-reviewed and published papers presenting the scientific case
for chemical exposures playing a role in breast cancer. The portfolio includes two principal
strands of compelling research. Firstly, large ongoing epidemiological studies and other
epidemiological studies suggesting an association between certain chemical exposures and breast
cancer that have not been contradicted by other studies. Secondly, papers illustrating
demonstrable changes in mammary tissue due to low level in-utero exposures to certain
chemicals in experimental animals. These papers will help take forward the discussion on the
mechanism of action. The purpose of the portfolio is to provide a useful resource for clinicians,
scientists, breast cancer charities, and other health professionals.
The portfolio has been compiled by Gwynne Lyons of CHEM Trust for HEAL and has been
reviewed by several international experts in the field. If in your opinion, other studies should be
included, please contact Gwynne Lyons at gwynne.lyons@chemtrust.org.uk.
The list of abstracts and full articles included in this portfolio:
*Brody J.G., Moysich K.B., Humblet O., Attfield K.R., Beehler G.P., Rudel R.A .(2007).
Environmental Pollutants and Breast Cancer-
http://www3.interscience.wiley.com/journal/114276685/issue], Cancer: Supplement:
Environmental Factors in Breast Cancer, Volume 109(12): 2667 – 2711
*Brophy J.T., Keith M.M., Gorey K.M., Luginaah I., Laukkanen E., Hellyer D., Reinhartz A.,
Watterson A,. Abu-Zahra H., Maticka-Tyndale E., Schneider K., Beck M., Gilbertson M. (2006).
[Occupation and breast cancer: a Canadian case-control study->
http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch
=17119253&ordinalpos=1&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubm
ed_RVDocSum], Annals of the New York Academy of Sciences, 1076:765-77.
-*Cassidy R.A., Natarajan S., Vaughan G.M. (2005). [The link between the insecticide
heptachlor epoxide, estradiol, and breast cancer-
>http://www.springerlink.com/content/vp12136434v26472/], Breast Cancer Research and
Treatment, 90(1):55-64.
-*Cohn B.A., Wolff M.S., Cirillo P.M., Sholtz R.I. (2007). [DDT and breast cancer in young
women: new data on the significance of age at exposure-
>http://www.ehponline.org/members/2007/10260/10260.pdf], Environmental Health Perspectives: Volume 115(10): 1406 - 1414 -*Darbre P.D. (2006). [Environmental oestrogens, cosmetics and breast cancer->http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6WBD-4JDTJ3H-B&_user=10&_coverDate=03%2F31%2F2006&_rdoc=10&_fmt=summary&_orig=browse&_srch=doc-info(%23toc%236708%232006%23999799998%23618260%23FLA%23display%23Volume)&_cdi=6708&_sort=d&_docanchor=&view=c&_ct=12&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=4006f015446d51466c50bdb2ab588ca6], Best Practice & Research Clinical Endocrinology & Metabolism, Volume 20(1): 121 - 143. -*Engel L.S., Hill D.A., Hoppin J.A., Lubin J.H., Lynch C.F., Pierce J., Samanic C., Sandler D.P., Blair A., Alavanja M.C. (2005). [Pesticide use and breast cancer risk among farmers' wives in the agricultural health study->http://aje.oxfordjournals.org/cgi/content/full/161/2/121], American Journal of Epidemiology, 161(2): 121 - 135. -*Fenton S.E. (2006). [Endocrine-disrupting compounds and mammary gland development: early exposure and later life consequences->http://endo.endojournals.org/cgi/content/full/147/6/s18?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&author1=Fenton&fulltext=Endocrine+&searchid=1&FIRSTINDEX=0&sortspec=relevance&volume=147&resourcetype=HWCIT], Endocrinology, 147(6 Suppl): S18 - 24. -*Fowler P.A., Gordon K.L., Throw C.A., Cash P., Miller D., Lea R.G., Rhind S.M. (2007). [Dietary sewage sludge exposure disrupts ewe mammogenesis->http://www.jointukfertility.co.uk/uploads/326/Full%20programme%20-%20APPROVED%20AS%20OF%2027.03.07.pdf], Poster at Fertility conference. Open the link and go to the page number 75 (Poster: P55). -*Ibarluzea J.M., Fernández M.F., Santa-Marina L., Olea-Serrano M.F., Rivas A.M., Aurrekoetxea J.J., Expósito J., Lorenzo M., Torné P., Villalobos M., Pedraza V., Sasco A.J., Olea N. (2004). [Breast cancer risk and the combined effect of environmental estrogens->http://www.springerlink.com/content/n87456r525082853/?p=e01a5ae6722b464fb8913b4f55ef4bc2&pi=7], Cancer Causes Control, 15(6): 591 - 600. -*Jenkins S., Rowell C., Wang J., Lamartiniere C.A. (2007). [Prenatal TCDD exposure predisposes for mammary cancer in rats->http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TC0-4M9RKJH-1&_user=10&_coverDate=05%2F31%2F2007&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=466162289e641cc2dc70a19c98277db9], Reproductive Toxicology, Volume 23 (3): 391 – 396 -*Kalantzi O., Hewitt R., Ford K., Alcock R., Thomas G., Morris J., Hewer A., Phillips D.H., Jones K. and Martin F.L. (2004) Inter-individual Differences in the Ablity of Human Milk-Fat Extracts To Enhance the Genotoxic Potential of the Procarcinogen Benzo[a]pyrene in MCF-7 Breast Cells [(Abstract)->http://pubs.acs.org/cgi-bin/abstract.cgi/esthag/2004/38/i13/abs/es035422y.html], Environmental Science and Technology, Volume 38(13): 3614 - 3622. -*Kortenkamp A. (2005). [Breast cancer, oestrogens and environmental pollutants: a re-evaluation from a mixture perspective->http://www.ncbi.nlm.nih.gov/sites/entrez?Db=pubmed&Cmd=ShowDetailView&TermToSearch=16466540&ordinalpos=6&itool=EntrezSystem2.PEntrez.Pubmed.Pubmed_ResultsPanel.Pubmed_RVDocSum], International Journal of Andrology, 29(1):193-8 -*Million Women Study Collaborators (2003). [Breast cancer and hormone-replacement therapy in the Million Women Study->http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T1B-497P4D3-7&_user=10&_coverDate=08%2F09%2F2003&_alid=603585566&_rdoc=2&_fmt=summary&_orig=search&_cdi=4886&_sort=d&_docanchor=&view=c&_ct=2&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=32cc642dc40acec72da9b4653a7cd4cf], Lancet. 9; 362(9382): 419 - 427. (Including erratum in: Lancet. 2003 Oct 4; 362(9390): 1160). -*Muñoz-de-Toro M., Markey C.M., Wadia P.R., Luque E.H., Rubin B.S., Sonnenschein C., Soto A.M. (2005). [Perinatal exposure to bisphenol-A alters peripubertal mammary gland development in mice->http://endo.endojournals.org/cgi/content/full/146/9/4138?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&searchid=1&FIRSTINDEX=0&sortspec=relevance&volume=146&firstpage=4138&resourcetype=HWCIT], Endocrinology, 146(9): 4138 - 4147. -*Murray T.J., Maffini M.V., Ucci A.A., Sonnenschein C., Soto A.M. (2007). [Induction of mammary gland ductal hyperplasias and carcinoma in situ following fetal bisphenol A exposure->http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TC0-4M62KBX-2&_user=10&_coverDate=05%2F31%2F2007&_rdoc=1&_fmt=&_orig=search&_sort=d&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=94e894bf7e33a02a31118ce25eb97e90], Reproductive Toxicology, 23(3): 383 - 390. -*Palmer J.R., Wise L.A., Hatch E.E., Troisi R., Titus-Ernstoff L., Strohsnitter W., Kaufman R., Herbst A.L., Noller K.L., Hyer M., Hoover R.N. (2006). [Prenatal diethylstilbestrol exposure and risk of breast cancer->http://cebp.aacrjournals.org/cgi/content/full/15/8/1509], Cancer Epidemiology, Biomarkers & Prevention, 15(8): 1509 - 1514. -*Rudel R.A., Attfield K.R., Schifano J.N., Brody J.G. (2007). [Chemicals causing mammary gland tumors in animals signal new directions for epidemiology, chemicals testing, and risk assessment for breast cancer prevention->http://www3.interscience.wiley.com/journal/114276685/issue], Cancer: Supplement: Environmental Factors in Breast Cancer, Volume 109(12): 2635 - 2666 -*Sasco A.J., Kaaks R., Little R.E. (2003). [Breast cancer: occurrence, risk factors and hormone metabolism->http://www.future-drugs.com/doi/abs/10.1586/14737140.3.4.546], Expert Review Anticancer Therapy, 3(4): 546 - 562. -*Snedeker S.M. (2006). Chemical exposures in the workplace: effect on breast cancer risk among women. AAOHN J. 54(6):270-9. -*Milena Durando, Laura Kass, Julio Piva, Carlos Sonnenschein, Ana M. Soto, Enrique H. Luque and Mónica Muñoz-de-Toro1 (2007). [Prenatal Bisphenol A Exposure Induces Preneoplastic Lesions in the Mammary Gland in Wistar Rats->http://www.ehponline.org/members/2006/9282/9282.pdf], Environmental Health Perspectives: Volume 115 (1): 80 - 86

Source: http://www.chemtrust.org.uk/wp-content/uploads/BC-Portfolio-of-papers.pdf