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Profyoshikawabook

1. Zen K, Yasui K, Nakajima T, Zen Y, Zen K, Gen Y, Mitsuyoshi H, Minami M, Mitsufuji S, Tanaka S, Itoh Y, Nakanuma Y, Taniwaki M, Arii S, Okanoue T, Yoshikawa T. ERK5 is a target for gene amplification at 17p11 and promotes cell growth in hepatocellular carcinoma by regulating mitotic entry. Genes 2. Taniguchi H, Sakagami J, Suzuki N, Hasegawa H, Shinoda M, Tosa M, Baba T, Yasuda H, Kataoka K, Yoshikawa T. Adenoendocrine cell carcinoma of the gallbladder clinically mimicking squamous cell carcinoma. Int J Clin Oncol 3. Takano H, Inoue KI, Shimada A, Sato H, Yanagisawa R, Yoshikawa T.
Urinary trypsin inhibitor protects against liver injury and coagulation pathway dysregulation induced by lipopolysaccharide/D-galactosamine in mice. Lab Invest 4. Takagi T, Naito Y, Inoue M, Akagiri S, Mizushima K, Handa O, Kokura S, Ichikawa H, Yoshikawa T. Inhalation of carbon monoxide ameliorates collagen-induced arthritis in mice and regulates the articular expression of IL-1beta and MCP-1. Inflammation 2009;32:83-8.
5. Piga R, Naito Y, Kokura S, Handa O, Yoshikawa T. Inhibitory effect of serotonin derivatives on high glucose-induced adhesion and migration of monocytes on human aortic endothelial cells. Br J Nutr 2009:1-9.
6. Omatsu T, Naito Y, Handa O, Hayashi N, Mizushima K, Qin Y, Hirata I, Adachi S, Okayama T, Kishimoto E, Takagi T, Kokura S, Ichikawa H, Yoshikawa T.
Involvement of reactive oxygen species in indomethacin-induced apoptosis of small intestinal epithelial cells. J Gastroenterol 2009;44 Suppl 19:30-4.
7. Okayama T, Yoshida N, Uchiyama K, Takagi T, Ichikawa H, Yoshikawa T.
Mast cells are involved in the pathogenesis of indomethacin-induced rat enteritis. J Gastroenterol 2009;44 Suppl 19:35-9.
8. Okayama T, Kokura S, Ishikawa T, Adachi S, Hattori T, Takagi T, Handa O, Naito Y, Yoshikawa T. Antitumor effect of pretreatment for colon cancer cells with hyperthermia plus geranylgeranylacetone in experimental metastasis models and a subcutaneous tumor model of colon cancer in mice. Int J Hyperthermia 9. Nomura K, Fujimoto Y, Yamashita M, Morimoto Y, Ohshiro M, Sato K, Oyake T, Kowata S, Konishi H, Yoshikawa T, Ishida Y, Taniwaki M. Absence of pseudomembranes in Clostridium difficile-associated diarrhea in patients using immunosuppression agents. Scand J Gastroenterol 2009;44:74-8.
10. Nin M, Katoh N, Kokura S, Handa O, Yoshikawa T, Kishimoto S.
Dichotomous effect of ultraviolet B on the expression of corneodesmosomal enzymes in human epidermal keratinocytes. J Dermatol Sci 2009;54:17-24.
11. Naito Y, Yoshikawa T. Oxidative Stress-Induced Posttranslational Modification of Proteins as a Target of Functional Food. Forum Nutr 12. Mitsuyoshi H, Yasui K, Harano Y, Endo M, Tsuji K, Minami M, Itoh Y, Okanoue T, Yoshikawa T. Analysis of hepatic genes involved in the metabolism of fatty acids and iron in nonalcoholic fatty liver disease. Hepatol Res 2009;39:366-73.
13. Hirata I, Naito Y, Handa O, Hayashi N, Mizushima K, Adachi S, Omatsu T, Okayama T, Kishimoto E, Ichikawa H, Takagi T, Kokura S, Otaka M, Yoshikawa T. Heat-Shock Protein 70-Overexpressing Gastric Epithelial Cells Are Resistant to Indomethacin-Induced Apoptosis. Digestion 2009;79:243-250.
14. Gen Y, Yasui K, Zen K, Nakajima T, Tsuji K, Endo M, Mitsuyoshi H, Minami M, Itoh Y, Tanaka S, Taniwaki M, Arii S, Okanoue T, Yoshikawa T. A novel amplification target, ARHGAP5, promotes cell spreading and migration by negatively regulating RhoA in Huh-7 hepatocellular carcinoma cells. Cancer Lett 15. Adachi S, Kokura S, Okayama T, Ishikawa T, Takagi T, Handa O, Naito Y, Yoshikawa T. Effect of hyperthermia combined with gemcitabine on apoptotic cell death in cultured human pancreatic cancer cell lines. Int J Hyperthermia 16. Tsubouchi Y, Fukuda W, Kawahito Y, Kohno M, Wada M, Ishino H, Hamaguchi M, Yamamoto A, Kadoya M, Niimi M, Yoshikawa T. A case of lupus nephritis improved after appropriately adjusting the dosage of mizoribine. Mod 17. Suzuki T, Yoshida N, Nakabe N, Isozaki Y, Kajikawa H, Takagi T, Handa O, Kokura S, Ichikawa H, Naito Y, Matsui H, Yoshikawa T. Prophylactic effect of rebamipide on aspirin-induced gastric lesions and disruption of tight junctional protein zonula occludens-1 distribution. J Pharmacol Sci 2008;106:469-77.
18. Soga K, Yamauchi J, Kawai Y, Yamada M, Uchikawa R, Tegoshi T, Mitsufuji S, Yoshikawa T, Arizono N. Alteration of the expression profiles of acidic mucin, sialytransferase, and sulfotransferases in the intestinal epithelium of rats infected with the nematode Nippostrongylus brasiliensis. Parasitol Res 19. Soga K, Tomikashi K, Miyawaki KI, Okuda K, Sugiyama Y, Sekikawa S, Wakabayashi N, Konishi H, Mitsufuji S, Kataoka K, Yoshikawa T. Endoscopic Injection Sclerotherapy with Ethanolamine Oleate with Iopamidol for Esophagojejunal Varices in Idiopathic Portal Hypertension. Dig Dis Sci 2008.
20. Okuda T, Yoshida N, Takagi T, Handa O, Kokura S, Ichikawa H, Naito Y, Yoshikawa T. CV-11974, angiotensin II type I receptor antagonist, reduces the severity of indomethacin-induced rat enteritis. Dig Dis Sci 2008;53:657-63.
21. Nomura K, Fujimoto Y, Yamashita M, Morimoto Y, Ohshiro M, Sato K, Oyake T, Kowata S, Konishi H, Yoshikawa T, Ishida Y, Taniwaki M. Absence of pseudomembranes in Clostridium difficile-associated diarrhea in patients using immunosuppression agents. Scand J Gastroenterol 2008:1-5.
22. Naito Y, Iinuma S, Yagi N, Boku Y, Imamoto E, Takagi T, Handa O, Kokura S, Yoshikawa T. Prevention of Indomethacin-Induced Gastric Mucosal Injury in Helicobacter pylori-Negative Healthy Volunteers: A Comparison Study Rebamipide vs Famotidine. J Clin Biochem Nutr 2008;43:34-40.
23. Miyagawa K, Sakakura C, Nakashima S, Yoshikawa T, Fukuda K, Kin S, Nakase Y, Shimomura K, Oue N, Yasui W, Hayasizaki H, Okazaki Y, Yamagishi H, Hagiwara A, Otsuji E. Overexpression of RegIV in peritoneal dissemination of gastric cancer and its potential as A novel marker for the detection of peritoneal micrometastasis. Anticancer Res 2008;28:1169-79.
24. Manabe E, Handa O, Naito Y, Mizushima K, Akagiri S, Adachi S, Takagi T, Kokura S, Maoka T, Yoshikawa T. Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling. J Cell Biochem 2008;103:1925-37.
25. Kawata E, Ashihara E, Kimura S, Takenaka K, Sato K, Tanaka R, Yokota A, Kamitsuji Y, Takeuchi M, Kuroda J, Tanaka F, Yoshikawa T, Maekawa T.
Administration of PLK-1 small interfering RNA with atelocollagen prevents the growth of liver metastases of lung cancer. Mol Cancer Ther 2008;7:2904-12.
26. Kawahito Y, Ichinose S, Sano H, Tsubouchi Y, Kohno M, Yoshikawa T, Tokunaga D, Hojo T, Harasawa R, Nakano T, Matsuda K. Mycoplasma fermentans glycolipid-antigen as a pathogen of rheumatoid arthritis. Biochem Biophys Res 27. Katada K, Yoshida N, Suzuki T, Okuda T, Mizushima K, Takagi T, Ichikawa H, Naito Y, Cepinskas G, Yoshikawa T. Dextran sulfate sodium-induced acute colonic inflammation in angiotensin II type 1a receptor deficient mice.
28. Kamitsuji Y, Kuroda J, Kimura S, Toyokuni S, Watanabe K, Ashihara E, Tanaka H, Yui Y, Watanabe M, Matsubara H, Mizushima Y, Hiraumi Y, Kawata E, Yoshikawa T, Maekawa T, Nakahata T, Adachi S. The Bcr-Abl kinase inhibitor INNO-406 induces autophagy and different modes of cell death execution in Bcr-Abl-positive leukemias. Cell Death Differ 2008;15:1712-1722.
29. Ito R, Kita M, Shin-Ya M, Kishida T, Urano A, Takada R, Sakagami J, Imanishi J, Iwakura Y, Okanoue T, Yoshikawa T, Kataoka K, Mazda O. Involvement of IL-17A in the pathogenesis of DSS-induced colitis in mice. Biochem Biophys 30. Ishino H, Kawahito Y, Tsubouchi Y, Kohno M, Wada M, Yamamoto A, Hamaguchi M, Kadoya M, Tokunaga D, Hojo T, Matsuyama M, Yoshimura R, Yoshikawa T. Feedback Control of the Arachidonate Cascade in Osteoblastic Cells by 15-deoxy-Delta-Prostaglandin J(2). J Clin Biochem Nutr 2008;42:64-9.
31. Hosoda H, Fukui M, Nakayama I, Asano M, Kadono M, Hasegawa G, Yoshikawa T, Nakamura N. Bone mass and bone resorption in postmenopausal women with type 2 diabetes mellitus. Metabolism 2008;57:940-5.
32. Hasegawa G, Kajiyama S, Tanaka T, Imai S, Kozai H, Fujinami A, Ohta M, Obayashi H, Park H, Nakano K, Tanaka M, Shiraishi E, Fukui M, Yoshikawa T, Nakamura N. The alpha-glucosidase inhibitor acarbose reduces the net electronegative charge of low-density lipoprotein in patients with newly diagnosed type 2 diabetes. Clin Chim Acta 2008;390:110-4.
33. Hamaguchi M, Kawahito Y, Omoto A, Tsubouchi Y, Kohno M, Seno T, Kadoya M, Yamamoto A, Ishino H, Matsuyama M, Yoshimura R, Yoshikawa T.
Eicosapentaenoic Acid suppresses the proliferation of synoviocytes from rheumatoid arthritis. J Clin Biochem Nutr 2008;43:126-8.
34. Fukui M, Tanaka M, Shiraishi E, Harusato I, Hosoda H, Asano M, Kadono M, Hasegawa G, Yoshikawa T, Nakamura N. Serum uric acid is associated with microalbuminuria and subclinical atherosclerosis in men with type 2 diabetes 35. Fukui M, Tanaka M, Kadono M, Imai S, Hasegawa G, Yoshikawa T, Nakamura N. Serum prostate-specific antigen levels in men with type 2 diabetes.
36. Fukui M, Tanaka M, Hasegawa G, Yoshikawa T, Nakamura N.
Association between serum bioavailable testosterone concentration and the ratio of glycated albumin to glycated hemoglobin in men with type 2 diabetes. Diabetes 37. Fukui M, Kitagawa Y, Kamiuchi K, Hasegawa G, Yoshikawa T, Nakamura N. Association between serum estradiol concentrations and carotid atherosclerosis in men with type 2 diabetes mellitus. Metabolism 2008;57:285-9.
38. Fukase K, Kato M, Kikuchi S, Inoue K, Uemura N, Okamoto S, Terao S, Amagai K, Hayashi S, Asaka M. Effect of eradication of Helicobacter pylori on incidence of metachronous gastric carcinoma after endoscopic resection of early gastric cancer: an open-label, randomised controlled trial. Lancet 2008;372:392-7.
39. Aoi W, Naito Y, Takanami Y, Ishii T, Kawai Y, Akagiri S, Kato Y, Osawa T, Yoshikawa T. Astaxanthin improves muscle lipid metabolism in exercise via inhibitory effect of oxidative CPT I modification. Biochem Biophys Res Commun 40. Ando T, Ishikawa T, Kokura S, Naito Y, Yoshida N, Yoshikawa T.
Endoscopic analysis of gastric ulcer after one week's treatment with omeprazole and rabeprazole in relation to CYP2C19 genotype. Dig Dis Sci 2008;53:933-7.
41. Akagiri S, Naito Y, Ichikawa H, Mizushima K, Takagi T, Handa O, Kokura S, Yoshikawa T. A Mouse Model of Metabolic Syndrome; Increase in Visceral Adipose Tissue Precedes the Development of Fatty Liver and Insulin Resistance in High-Fat Diet-Fed Male KK/Ta Mice. J Clin Biochem Nutr 42. Akagiri S, Naito Y, Ichikawa H, Mizushima K, Takagi T, Handa O, Kokura S, Yoshikawa T. Bofutsushosan, an Oriental Herbal Medicine, Attenuates the Weight Gain of White Adipose Tissue and the Increased Size of Adipocytes Associated with the Increase in Their Expression of Uncoupling Protein 1 in High-Fat Diet-Fed Male KK/Ta mice. J Clin Biochem Nutr 2008;42:158-66.
43. Akabame S, Hamaguchi M, Tomiyasu K, Tanaka M, Kobayashi-Takenaka Y, Nakano K, Oda Y, Yoshikawa T. Evaluation of vulnerable coronary plaques and non-alcoholic fatty liver disease (NAFLD) by 64-detector multislice computed tomography (MSCT). Circ J 2008;72:618-25.
44. Yuba T, Nagata K, Yamada T, Osugi S, Kuwahara H, Iwasaki Y, Handa O, Naito Y, Fushiki S, Yoshikawa T, Marunaka Y. A novel potent inhibitor of inducible nitric oxide synthase, ONO-1714, reduces hyperoxic lung injury in mice. Respir 45. Yoshida N, Katada K, Handa O, Takagi T, Kokura S, Naito Y, Mukaida N, Soma T, Shimada Y, Yoshikawa T, Okanoue T. Interleukin-8 production via protease-activated receptor 2 in human esophageal epithelial cells. Int J Mol Med 46. Wada M, Kawahito Y, Kimura S, Kohno M, Ishino H, Kimura M, Omoto A, Yamamoto A, Hamaguchi M, Tsubouchi Y, Tokunaga D, Hojo T, Ashihara E, Maekawa T, Yoshikawa T. siRNA targeting PLK-1 induces apoptosis of synoviocytes in rheumatoid arthritis. Biochem Biophys Res Commun 47. Tsuboi H, Naito Y, Katada K, Takagi T, Handa O, Kokura S, Ichikawa H, Yoshida N, Tsukada M, Yoshikawa T. Role of the thrombin/protease-activated receptor 1 pathway in intestinal ischemia-reperfusion injury in rats. Am J Physiol Gastrointest Liver Physiol 2007;292:G678-83.
48. Sakakura C, Miyagawa K, Fukuda KI, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Ida H, Yazumi S, Yamagishi H, Okanoue T, Chiba T, Ito K, Hagiwara A, Ito Y. Frequent silencing of RUNX3 in esophageal squamous cell carcinomas is associated with radioresistance and poor prognosis. Oncogene 2007;26:5927-38.
49. Piga R, Naito Y, Kokura S, Handa O, Yoshikawa T. Short-term high glucose exposure induces monocyte-endothelial cells adhesion and transmigration by increasing VCAM-1 and MCP-1 expression in human aortic endothelial cells.
50. Okuda T, Yoshida N, Takagi T, Handa O, Kokura S, Ichikawa H, Naito Y, Yoshikawa T. CV-11974, angiotensin II type I receptor antagonist, reduces the severity of indomethacin-induced rat enteritis. Dig Dis Sci 2007.
51. Nakashima S, Nakamura T, Miyagawa K, Yoshikawa T, Kin S, Kuriu Y, Nakase Y, Sakakura C, Otsuji E, Hagiwara A, Yamagishi H. In situ tissue engineering of the bile duct using polypropylene mesh-collagen tubes. Int J Artif 52. Nakase Y, Nakamura T, Kin S, Nakashima S, Yoshikawa T, Kuriu Y, Miyagawa K, Sakakura C, Otsuji E, Ikada Y, Yamagishi H, Hagiwara A. Endocrine cell and nerve regeneration in autologous in situ tissue-engineered small intestine. J 53. Nakabe N, Kokura S, Shimozawa M, Katada K, Sakamoto N, Ishikawa T, Handa O, Takagi T, Naito Y, Yoshida N, Yoshikawa T. Hyperthermia attenuates TNF-alpha-induced up regulation of endothelial cell adhesion molecules in human arterial endothelial cells. Int J Hyperthermia 2007;23:217-24.
54. Naito Y, Takagi T, Yoshikawa T. Molecular fingerprints of neutrophil-dependent oxidative stress in inflammatory bowel disease. J 55. Manabe E, Handa O, Naito Y, Mizushima K, Akagiri S, Adachi S, Takagi T, Kokura S, Maoka T, Yoshikawa T. Astaxanthin protects mesangial cells from hyperglycemia-induced oxidative signaling. J Cell Biochem 2007.
56. Kokura S, Yoshida N, Okuda T, Nakabe N, Sakamoto N, Isozaki Y, Hattori T, Handa O, Takagi T, Naito Y, Yoshikawa T. Hyperthermia ameliorates 2,4,6-trinitrobenzene sulphonic acid-induced colitis in rats: the role of heat shock proteins. Int J Hyperthermia 2007;23:17-28.
57. Kokura S, Adachi S, Manabe E, Mizushima K, Hattori T, Okuda T, Nakabe N, Handa O, Takagi T, Naito Y, Yoshida N, Yoshikawa T. Whole body hyperthermia improves obesity-induced insulin resistance in diabetic mice. Int J 58. Kobayashi Y, Kamitsuji Y, Kuroda J, Tsunoda S, Uoshima N, Kimura S, Wada K, Matsumoto Y, Nomura K, Horiike S, Shimazaki C, Yoshikawa T, Taniwaki M. Comparison of human herpes virus 8 related primary effusion lymphoma with human herpes virus 8 unrelated primary effusion lymphoma-like lymphoma on the basis of HIV: report of 2 cases and review of 212 cases in the literature. Acta 59. Kitamura R, Takahashi T, Nakajima N, Isodono K, Asada S, Ueno H, Ueyama T, Yoshikawa T, Matsubara H, Oh H. Stage-specific role of endogenous Smad2 activation in cardiomyogenesis of embryonic stem cells. Circ Res 60. Kin S, Hagiwara A, Nakase Y, Kuriu Y, Nakashima S, Yoshikawa T, Sakakura C, Otsuji E, Nakamura T, Yamagishi H. Regeneration of skeletal muscle using in situ tissue engineering on an acellular collagen sponge scaffold in a rabbit 61. Kimura M, Kawahito Y, Obayashi H, Ohta M, Hara H, Adachi T, Tokunaga D, Hojo T, Hamaguchi M, Omoto A, Ishino H, Wada M, Kohno M, Tsubouchi Y, Yoshikawa T. A critical role for allograft inflammatory factor-1 in the pathogenesis of rheumatoid arthritis. J Immunol 2007;178:3316-22.
62. Kimura M, Kawahito Y, Hamaguchi M, Nakamura T, Okamoto M, Matsumoto Y, Endo H, Yamamoto A, Ishino H, Wada M, Omoto A, Tsubouchi Y, Kohno M, Yoshikawa T. SKL-2841, a dual antagonist of MCP-1 and MIP-1 beta, prevents bleomycin-induced skin sclerosis in mice. Biomed Pharmacother 63. Handa O, Naito Y, Yoshikawa T. CagA protein of Helicobacter pylori: a hijacker of gastric epithelial cell signaling. Biochem Pharmacol 2007;73:1697-702.
64. Hamaguchi M, Kojima T, Takeda N, Nagata C, Takeda J, Sarui H, Kawahito Y, Yoshida N, Suetsugu A, Kato T, Okuda J, Ida K, Yoshikawa T.
Nonalcoholic fatty liver disease is a novel predictor of cardiovascular disease. World 65. Hamaguchi M, Kojima T, Itoh Y, Harano Y, Fujii K, Nakajima T, Kato T, Takeda N, Okuda J, Ida K, Kawahito Y, Yoshikawa T, Okanoue T. The Severity of Ultrasonographic Findings in Nonalcoholic Fatty Liver Disease Reflects the Metabolic Syndrome and Visceral Fat Accumulation. Am J Gastroenterol 2007.
66. Hamaguchi M, Kawahito Y, Tsubouchi Y, Kohno M, Yamamoto A, Ishino H, Wada M, Yoshikawa T. Combination therapy of prednisolone and mizoribine improves cryoglobulinemic vasculitis with purpura and skin ulcers. Clin Rheumatol 67. Fukui M, Ose H, Nakayama I, Hosoda H, Asano M, Kadono M, Mogami SI, Hasegawa G, Yoshikawa T, Nakamura N. Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentration in women with type 2 diabetes. Diabetes Care 2007.
68. Fukui M, Ose H, Nakayama I, Hosoda H, Asano M, Kadono M, Mogami S, Yamazaki M, Hasegawa G, Yoshikawa T, Nakamura N. Association between serum testosterone concentration and collagen degradation fragments in men with type 2 diabetes mellitus. Metabolism 2007;56:1228-32.
69. Fukui M, Ose H, Nakayama I, Hosoda H, Asano M, Kadono M, Mogami S, Hasegawa G, Yoshikawa T, Nakamura N. Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentrations in women with type 2 diabetes. Diabetes Care 2007;30:1886-8.
70. Fukui M, Ose H, Kitagawa Y, Yamazaki M, Hasegawa G, Yoshikawa T, Nakamura N. Relationship between low serum endogenous androgen concentrations and arterial stiffness in men with type 2 diabetes mellitus. Metabolism 71. Fukui M, Ose H, Kitagawa Y, Kamiuchi K, Nakayama I, Ohta M, Obayashi H, Yamasaki M, Hasegawa G, Yoshikawa T, Nakamura N. Metabolic syndrome is not associated with markers of subclinical atherosclerosis, serum adiponectin and endogenous androgen concentrations in Japanese men with Type 2 diabetes. Diabet Med 2007;24:864-71.
72. Fukui M, Ose H, Hasegawa G, Yoshikawa T, Nakamura N. Association between urinary albumin excretion and plasma 5-hydroxyindole-3-acetic acid concentration in men with type 2 diabetes. Diabetes Care 2007;30:2649-51.
73. Aoi W, Niisato N, Sawabe Y, Miyazaki H, Tokuda S, Nishio K, Yoshikawa T, Marunaka Y. Abnormal expression of ENaC and SGK1 mRNA induced by dietary sodium in Dahl salt-sensitively hypertensive rats. Cell Biol Int 74. Aoi W, Naito Y, Nakamura T, Akagiri S, Masuyama A, Takano T, Mizushima K, Yoshikawa T. Inhibitory effect of fermented milk on delayed-onset muscle damage after exercise. J Nutr Biochem 2007;18:140-5.
75. Yoshida N, Isozaki Y, Takagi T, Takenaka S, Uchikawa R, Arizono N, Yoshikawa T, Okanoue T. Review article: anti-tryptase therapy in inflammatory bowel disease. Aliment Pharmacol Ther 2006;24 Suppl 4:249-55.
76. Yoshida N, Imamoto E, Uchiyama K, Kuroda M, Naito Y, Mukaida N, Kawabe A, Shimada Y, Yoshikawa T, Okanoue T. Molecular mechanisms involved in interleukin-8 production by normal human oesophageal epithelial cells. Aliment Pharmacol Ther 2006;24 Suppl 4:219-26.
77. Yamaguchi T, Kamada K, Dayton C, Gaskin FS, Yusof M, Yoshikawa T, Carter P, Korthuis RJ. Role of eNOS-derived NO in the Postischemic Anti-inflammatory Effects of Antecedent Ethanol Ingestion in Murine Small Intestine. Am J Physiol Heart Circ Physiol 2006.
78. Takagi T, Yoshida N, Isozaki Y, Shimozawa M, Katada K, Manabe H, Hanada O, Kokura S, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. CV-11974, angiotensin II type I receptor antagonist, protects against ischemia-reperfusion injury of the small intestine in rats. Eur J Pharmacol 2006;535:283-90.
79. Takagi T, Naito Y, Tsuboi H, Isozaki Y, Katada K, Suzuki T, Terao K, Handa O, Kokura S, Ichikawa H, Yoshida N, Okuyama Y, Yagi N, Ueda H, Yoshikawa T. Increased intestinal luminal carbon monoxide gas in patients with ulcerative colitis. Aliment Pharmacol Ther 2006;24 Suppl 4:233-8.
80. Sugimoto N, Yoshida N, Nakamura Y, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. Influence of vitamin E on gastric mucosal injury induced by Helicobacter pylori infection. Biofactors 2006;28:9-19.
81. Ohnishi M, Hasegawa G, Yamasaki M, Obayashi H, Fukui M, Nakajima T, Ichida Y, Ohse H, Mogami S, Yoshikawa T, Nakamura N. Integrin-linked kinase acts as a pro-survival factor against high glucose-associated osmotic stress in human mesangial cells. Nephrol Dial Transplant 2006;21:1786-93.
82. Nakajima T, Hasegawa G, Kamiuchi K, Fukui M, Yamasaki M, Tominaga M, Asano M, Hosoda H, Yoshikawa T, Nakamura N. Differential regulation of intracellular redox state by extracellular matrix proteins in glomerular mesangial cells: potential role in diabetic nephropathy. Redox Rep 2006;11:223-30.
83. Naito Y, Yoshikawa T. Oxidative stress involvement and gene expression in indomethacin-induced gastropathy. Redox Rep 2006;11:243-53.
84. Naito Y, Uchiyama K, Mizushima K, Kuroda M, Akagiri S, Takagi T, Handa O, Kokura S, Yoshida N, Ichikawa H, Takahashi J, Yoshikawa T. Microarray profiling of gene expression patterns in glomerular cells of astaxanthin-treated diabetic mice: a nutrigenomic approach. Int J Mol Med 2006;18:685-95.
85. Naito Y, Uchiyama K, Kuroda M, Takagi T, Kokura S, Yoshida N, Ichikawa H, Yoshikawa T. Role of pancreatic trypsin in chronic esophagitis induced by gastroduodenal reflux in rats. J Gastroenterol 2006;41:198-208.
86. Naito Y, Takagi T, Mizushima K, Ueta M, Kinoshita S, Handa O, Kokura S, Ichikawa H, Yoshida N, Yoshikawa T. Gene expression clusters of a lipopolysaccharide-stimulated pathway in peripheral blood monocytes of Japanese patients with Crohn's disease. Aliment Pharmacol Ther 2006;24 Suppl 4:256-65.
87. Naito Y, Takagi T, Katada K, Uchiyama K, Kuroda M, Kokura S, Ichikawa H, Watabe J, Yoshida N, Okanoue T, Yoshikawa T. Partially hydrolyzed guar gum down-regulates colonic inflammatory response in dextran sulfate sodium-induced colitis in mice. J Nutr Biochem 2006;17:402-9.
88. Naito Y, Shimozawa M, Manabe H, Nakabe N, Katada K, Kokura S, Yoshida N, Ichikawa H, Kon T, Yoshikawa T. Azelnidipine, a new calcium channel blocker, inhibits endothelial inflammatory response by reducing intracellular levels of reactive oxygen species. Eur J Pharmacol 2006;546:11-8.
89. Naito Y, Kuroda M, Uchiyama K, Mizushima K, Akagiri S, Takagi T, Handa O, Kokura S, Yoshida N, Ichikawa H, Yoshikawa T. Inflammatory response of esophageal epithelium in combined-type esophagitis in rats: a transcriptome analysis. Int J Mol Med 2006;18:821-8.
90. Naito Y, Katada K, Takagi T, Tsuboi H, Kuroda M, Handa O, Kokura S, Yoshida N, Ichikawa H, Yoshikawa T. Rosuvastatin reduces rat intestinal ischemia-reperfusion injury associated with the preservation of endothelial nitric oxide synthase protein. World J Gastroenterol 2006;12:2024-30.
91. Naito Y, Katada K, Takagi T, Tsuboi H, Isozaki Y, Handa O, Kokura S, Yoshida N, Ichikawa H, Yoshikawa T. Rosuvastatin, a new HMG-CoA reductase inhibitor, reduces the colonic inflammatory response in dextran sulfate sodium-induced colitis in mice. Int J Mol Med 2006;17:997-1004.
92. Miyagawa K, Sakakura C, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Ito K, Yamagishi H, Ida H, Yazumi S, Chiba T, Ito Y, Hagiwara A. Down-regulation of RUNX1, RUNX3 and CBFbeta in hepatocellular carcinomas in an early stage of hepatocarcinogenesis. Anticancer Res 2006;26:3633-43.
93. Kuroda M, Yoshida N, Ichikawa H, Takagi T, Okuda T, Naito Y, Okanoue T, Yoshikawa T. Lansoprazole, a proton pump inhibitor, reduces the severity of indomethacin-induced rat enteritis. Int J Mol Med 2006;17:89-93.
94. Kitawaki J, Kiyomizu M, Obayashi H, Ohta M, Ishihara H, Hasegawa G, Nakamura N, Yoshikawa T, Honjo H. Synergistic effect of interleukin-6 promoter (IL6 -634C/G) and intercellular adhesion molecule-1 (ICAM-1 469K/E) gene polymorphisms on the risk of endometriosis in Japanese women. Am J Reprod 95. Kimura M, Kawahito Y, Hamaguchi M, Nakamura T, Okamoto M, Matsumoto Y, Endo H, Yamamoto A, Ishino H, Wada M, Omoto A, Tsubouchi Y, Kohno M, Yoshikawa T. SKL-2841, a dual antagonist of MCP-1 and MIP-1 beta, prevents bleomycin-induced skin sclerosis in mice. Biomed Pharmacother 2006.
96. Katada K, Naito Y, Mizushima K, Takagi T, Handa O, Kokura S, Ichikawa H, Yoshida N, Matsui H, Yoshikawa T. Gene expression profiles on hypoxia and reoxygenation in rat gastric epithelial cells: a high-density DNA microarray analysis.
97. Isozaki Y, Yoshida N, Kuroda M, Takagi T, Handa O, Kokura S, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. Effect of a novel water-soluble vitamin E derivative as a cure for TNBS-induced colitis in rats. Int J Mol Med 98. Isozaki Y, Yoshida N, Kuroda M, Handa O, Takagi T, Kokura S, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. Anti-tryptase treatment using nafamostat mesilate has a therapeutic effect on experimental colitis. Scand J Gastroenterol 99. Iida Y, Oda Y, Nakamori S, Tsunoda S, Kishida T, Gojo S, Shin-Ya M, Asada H, Imanishi J, Yoshikawa T, Matsubara H, Mazda O. Transthoracic direct current shock facilitates intramyocardial transfection of naked plasmid DNA infused via coronary vessels in canines. Gene Ther 2006;13:906-16.
100. Ichida Y, Hasegawa G, Fukui M, Obayashi H, Ohta M, Fujinami A, Ohta K, Nakano K, Yoshikawa T, Nakamura N. Effect of atorvastatin on in vitro expression of resistin in adipocytes and monocytes/macrophages and effect of atorvastatin treatment on serum resistin levels in patients with type 2 diabetes.
101. Handa O, Yoshida N, Fujita N, Tanaka Y, Ueda M, Takagi T, Kokura S, Naito Y, Okanoue T, Yoshikawa T. Molecular mechanisms involved in anti-inflammatory effects of proton pump inhibitors. Inflamm Res 2006;55:476-80.
102. Handa O, Kokura S, Adachi S, Takagi T, Naito Y, Tanigawa T, Yoshida N, Yoshikawa T. Methylparaben potentiates UV-induced damage of skin keratinocytes.
103. Hamaguchi M, Kawahito Y, Tsubouchi Y, Kohno M, Yamamoto A, Ishino H, Wada M, Yoshikawa T. Combination therapy of prednisolone and mizoribine improves cryoglobulinemic vasculitis with purpura and skin ulcers. Clin Rheumatol 104. Fukui M, Kitagawa Y, Kamiuchi K, Hasegawa G, Yoshikawa T, Nakamura N. Low serum dehydroepiandrosterone sulfate concentration is a predictor for deterioration of urinary albumin excretion in male patients with type 2 diabetes. Diabetes Res Clin Pract 2006;73:47-50.
105. Yoshikawa T, Kawahito Y. [Autoimmune disease]. Nippon Rinsho 106. Yamaguchi T, Yoshida N, Tomatsuri N, Takayama R, Katada K, Takagi T, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. Cytokine-induced neutrophil accumulation in the pathogenesis of acute reflux esophagitis in rats. Int J Mol Med 107. Wada S, Satomi Y, Murakoshi M, Noguchi N, Yoshikawa T, Nishino H.
Tumor suppressive effects of tocotrienol in vivo and in vitro. Cancer Lett 108. Ueda-Nishimura T, Niisato N, Miyazaki H, Naito Y, Yoshida N, Yoshikawa T, Nishino H, Marunaka Y. Synergic action of insulin and genistein on Na+/K+/2Cl- cotransporter in renal epithelium. Biochem Biophys Res Commun 109. Tsunoda S, Mazda O, Oda Y, Iida Y, Akabame S, Kishida T, Shin-Ya M, Asada H, Gojo S, Imanishi J, Matsubara H, Yoshikawa T. Sonoporation using microbubble BR14 promotes pDNA/siRNA transduction to murine heart. Biochem 110. Takakura Y, Yoshioka K, Umekawa T, Kogure A, Toda H, Yoshikawa T, Yoshida T. Thr54 allele of the FABP2 gene affects resting metabolic rate and visceral obesity. Diabetes Res Clin Pract 2005;67:36-42.
111. Sakamoto N, Kokura S, Okuda T, Hattori T, Katada K, Isozaki Y, Nakabe N, Handa O, Takagi T, Ishikawa T, Naito Y, Yoshida N, Yoshikawa T. Heme oxygenase-1 (Hsp32) is involved in the protection of small intestine by whole body mild hyperthermia from ischemia/reperfusion injury in rat. Int J Hyperthermia 112. Sakakura C, Miyagawa K, Fukuda K, Kin S, Nakase Y, Kuriu Y, Nakashima S, Yoshikawa T, Yamaoka N, Sagara Y, Hagiwara A, Yamagishi H. [A long-term survival case with multiple liver metastases from duodenal gastrointestinal stromal tumor that was drastically reduced by the treatment with imatinib]. Gan To Kagaku Ryoho 2005;32:1739-41.
113. Sakakura C, Hasegawa K, Miyagawa K, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Yazumi S, Yamagishi H, Okanoue T, Chiba T, Hagiwara A. Possible involvement of RUNX3 silencing in the peritoneal metastases of gastric cancers.
114. Sakakura C, Hagiwara A, Yoshikawa T, Hamada T, Yamagishi H. Huge ovarian metastasis from jejunal cancer occurring immediately after initial operation.
Hepatogastroenterology 2005;52:425-8.
115. Sakakura C, Hagiwara A, Miyagawa K, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Ito K, Yamagishi H, Yazumi S, Chiba T, Ito Y. Frequent downregulation of the runt domain transcription factors RUNX1, RUNX3 and their cofactor CBFB in gastric cancer. Int J Cancer 2005;113:221-8.
116. Ose H, Fukui M, Kitagawa Y, Hirata C, Ichio N, Kadono M, Mogami S, Onishi M, Ichida Y, Nakajima T, Hasegawa G, Yoshikawa T, Nakamura N. Efficacy of glimepiride in patients with poorly controlled insulin-treated type 2 diabetes 117. Omoto A, Kawahito Y, Prudovsky I, Tubouchi Y, Kimura M, Ishino H, Wada M, Yoshida M, Kohno M, Yoshimura R, Yoshikawa T, Sano H. Copper chelation with tetrathiomolybdate suppresses adjuvant-induced arthritis and inflammation-associated cachexia in rats. Arthritis Res Ther 2005;7:R1174-82.
118. Nakamura M, Asada M, Atsuda K, Matsui H, Watanabe T, Higuchi K, Arakawa T, Hibi N, Tsuchimoto K. Lansoprazole binding to the neutrophils in dextran sulfate sodium-induced rat colitis. Inflammopharmacology 2005;13:303-15.
119. Naito Y, Yoshikawa T. Role of matrix metalloproteinases in inflammatory bowel disease. Mol Aspects Med 2005;26:379-90.
120. Naito Y, Yoshikawa T. [Role of nitric oxide derived from inducible nitric oxide synthase in H. pylori-infected gastric mucosal injury]. Nippon Rinsho 121. Naito Y, Takano H, Yoshikawa T. Oxidative stress-related molecules as a therapeutic target for inflammatory and allergic diseases. Curr Drug Targets 122. Naito Y, Shimozawa M, Kuroda M, Nakabe N, Manabe H, Katada K, Kokura S, Ichikawa H, Yoshida N, Noguchi N, Yoshikawa T. Tocotrienols reduce 25-hydroxycholesterol-induced monocyte-endothelial cell interaction by inhibiting the surface expression of adhesion molecules. Atherosclerosis 2005;180:19-25.
123. Naito Y, Mizushima K, Yoshikawa T. Global analysis of gene expression in gastric ischemia-reperfusion: a future therapeutic direction for mucosal protective drugs. Dig Dis Sci 2005;50 Suppl 1:S45-55.
124. Naito Y, Kajikawa H, Mizushima K, Shimozawa M, Kuroda M, Katada K, Takagi T, Handa O, Kokura S, Ichikawa H, Yoshida N, Matsui H, Yoshikawa T.
Rebamipide, a gastro-protective drug, inhibits indomethacin-induced apoptosis in cultured rat gastric mucosal cells: association with the inhibition of growth arrest and DNA damage-induced 45 alpha expression. Dig Dis Sci 2005;50 Suppl 125. Naito Y, Akagiri S, Uchiyama K, Kokura S, Yoshida N, Hasegawa G, Nakamura N, Ichikawa H, Toyokuni S, Ijichi T, Yoshikawa T. Reduction of diabetes-induced renal oxidative stress by a cantaloupe melon extract/gliadin biopolymers, oxykine, in mice. Biofactors 2005;23:85-95.
126. Miyagawa K, Sakakura C, Nakashima S, Yoshikawa T, Kin S, Nakase Y, Fukuda K, Hagiwara A, Okazaki Y, Hayashizaki Y, Yamagishi H. [Analysis of Reg IV expression in peritoneal dissemination of gastric cancer using real-time RT-PCR].
127. Kokura S, Yoshida N, Sakamoto N, Ishikawa T, Takagi T, Higashihara H, Nakabe N, Handa O, Naito Y, Yoshikawa T. The radical scavenger edaravone enhances the anti-tumor effects of CPT-11 in murine colon cancer by increasing apoptosis via inhibition of NF-kappaB. Cancer Lett 2005;229:223-33.
128. Kokura S, Yoshida N, Ishikawa T, Higashihara H, Sakamoto N, Takagi T, Uchiyama K, Naito Y, Mazda O, Okanoue T, Yoshikawa T. Interleukin-10 plasmid DNA inhibits subcutaneous tumor growth of Colon26 adenocarcinoma in mice.
129. Kogure A, Yoshida T, Takakura Y, Umekawa T, Hioki C, Yoshioka K, Yoshimoto K, Yoshikawa T. Effect of ultrasonic stimulation on mRNA abundance of uncoupling protein (UCP) 2 and UCP 3 in gastrocnemius muscle of rats. Clin Exp 130. Katada K, Yoshida N, Isozaki Y, Tomatsuri N, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. Prevention by rebamipide of acute reflux esophagitis in rats. Dig Dis Sci 2005;50 Suppl 1:S97-S103.
131. Isozaki Y, Yoshida N, Ichikawa H, Kuroda M, Kokura S, Naito Y, Okanoue T, Yoshikawa T. A novel water-soluble vitamin E derivative protects against aspirin-induced gastric mucosal injury in rats. Int J Mol Med 132. Ishii M, Hasegawa G, Fukui M, Obayashi H, Ohta M, Ogata M, Yoshioka K, Kitagawa Y, Nakano K, Yoshikawa T, Nakamura N. Clinical and genetic characteristics of diabetic patients with high-titer (>10,000 U/ml) of antibodies to glutamic acid decarboxylase. Immunol Lett 2005;99:180-5.
133. Inoue K, Takano H, Yanagisawa R, Sakurai M, Shimada A, Sato H, Kato Y, Yoshikawa T. Antioxidative role of urinary trypsin inhibitor in acute lung injury induced by lipopolysaccharide. Int J Mol Med 2005;16:1029-33.
134. Hasegawa G, Yamamoto Y, Zhi JG, Tanino Y, Yamasaki M, Yano M, Nakajima T, Fukui M, Yoshikawa T, Nakamura N. Daily profile of plasma %CoQ10 level, a biomarker of oxidative stress, in patients with diabetes manifesting postprandial hyperglycaemia. Acta Diabetol 2005;42:179-81.
135. Hasegawa G, Ohta M, Ichida Y, Obayashi H, Shigeta M, Yamasaki M, Fukui M, Yoshikawa T, Nakamura N. Increased serum resistin levels in patients with type 2 diabetes are not linked with markers of insulin resistance and adiposity.
136. Fukui M, Kitagawa Y, Nakamura N, Kadono M, Hasegawa G, Yoshikawa T. Association between alcohol consumption and serum dehydroepiandrosterone sulphate concentration in men with Type 2 diabetes: a link to decreased cardiovascular risk. Diabet Med 2005;22:1446-50.
137. Yoshikawa T, Hagiwara A, Nakashima S, Miyagawa K, Kuriu Y, Kin S, Nakase Y, Fukuda K, Sakakura C, Otsuji E, Sonoyama T, Yamagishi H. [A trial of the new procedure of sentinel node biopsy in the lower rectal cancer by a transsacral approach]. Gan To Kagaku Ryoho 2004;31:1746-8.
138. Yoshikawa K, Nakata Y, Yamada K, Nakagawa M. Early pathological changes in the parkinsonian brain demonstrated by diffusion tensor MRI. J Neurol 139. Yoshida T, Shiga K, Yoshikawa K, Yamada K, Nakagawa M. White matter loss in the splenium of the corpus callosum in a case of posterior cortical atrophy: a diffusion tensor imaging study. Eur Neurol 2004;52:77-81.
140. Yoshida N, Uchiyama K, Kuroda M, Sakuma K, Kokura S, Ichikawa H, Naito Y, Takemura T, Yoshikawa T, Okanoue T. Interleukin-8 expression in the esophageal mucosa of patients with gastroesophageal reflux disease. Scand J 141. Yoshida N, Kassai K, Murase H, Tanaka Y, Kokura S, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. Effects of Helicobacter pylori water extract on expression of endothelial adhesion molecules. Can J Gastroenterol 2004;18:387-91.
142. Yano M, Hasegawa G, Ishii M, Yamasaki M, Fukui M, Nakamura N, Yoshikawa T. Short-term exposure of high glucose concentration induces generation of reactive oxygen species in endothelial cells: implication for the oxidative stress associated with postprandial hyperglycemia. Redox Rep 2004;9:111-6.
143. Uchiyama K, Takano H, Yanagisawa R, Inoue K, Naito Y, Yoshida N, Yoshino S, Murase H, Ichinose T, Yoshikawa T. A novel water-soluble vitamin E derivative prevents acute lung injury by bacterial endotoxin. Clin Exp Pharmacol 144. Tomatsuri N, Yoshida N, Takagi T, Katada K, Isozaki Y, Imamoto E, Uchiyama K, Kokura S, Ichikawa H, Naito Y, Okanoue T, Yoshikawa T. Edaravone, a newly developed radical scavenger, protects against ischemia-reperfusion injury of the small intestine in rats. Int J Mol Med 2004;13:105-9.
145. Teramoto M, Kitawaki J, Koshiba H, Kitaoka Y, Obayashi H, Hasegawa G, Nakamura N, Yoshikawa T, Matsushita M, Maruya E, Saji H, Ohta M, Honjo H.
Genetic contribution of tumor necrosis factor (TNF)-alpha gene promoter (-1031, -863 and -857) and TNF receptor 2 gene polymorphisms in endometriosis susceptibility. Am J Reprod Immunol 2004;51:352-7.
146. Takano H, Osakabe N, Sanbongi C, Yanagisawa R, Inoue K, Yasuda A, Natsume M, Baba S, Ichiishi E, Yoshikawa T. Extract of Perilla frutescens enriched for rosmarinic acid, a polyphenolic phytochemical, inhibits seasonal allergic rhinoconjunctivitis in humans. Exp Biol Med (Maywood) 2004;229:247-54.
147. Takagi T, Naito Y, Ichikawa H, Tomatsuri N, Katada K, Isozaki Y, Kuroda M, Kokura S, Yoshida N, Yoshikawa T. A PPAR-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J(2), inhibited gastric mucosal injury induced by ischemia-reperfusion in rats. Redox Rep 2004;9:376-81.
148. Shimozawa M, Naito Y, Manabe H, Uchiyama K, Kuroda M, Katada K, Yoshida N, Yoshikawa T. 7-Ketocholesterol enhances the expression of adhesion molecules on human aortic endothelial cells by increasing the production of reactive oxygen species. Redox Rep 2004;9:370-5.
149. Shimozawa M, Naito Y, Manabe H, Uchiyama K, Katada K, Kuroda M, Nakabe N, Yoshida N, Yoshikawa T. The inhibitory effect of alacepril, an angiotensin-converting enzyme inhibitor, on endothelial inflammatory response induced by oxysterol and TNF-alpha. Redox Rep 2004;9:354-9.
150. Sakakura C, Takemura M, Miyagawa K, Fukuda K, Shimomura K, Kin S, Nakase Y, Kuriu Y, Nakashima S, Yoshikawa T, Ueda Y, Fujiyama J, Sonoyama T, Okazaki Y, Hayashizaki Y, Hagiwara A, Yamagishi H. [Utility of dopa decarboxylase as a novel marker for the detection of peritoneal micro-metastases of gastric cancer with realtime RT-PCR]. Gan To Kagaku Ryoho 2004;31:1906-8.
151. Sakakura C, Takemura M, Hagiwara A, Shimomura K, Miyagawa K, Nakashima S, Yoshikawa T, Takagi T, Kin S, Nakase Y, Fujiyama J, Hayasizaki Y, Okazaki Y, Yamagishi H. Overexpression of dopa decarboxylase in peritoneal dissemination of gastric cancer and its potential as a novel marker for the detection of peritoneal micrometastases with real-time RT-PCR. Br J Cancer 2004;90:665-71.
152. Omoto A, Kawahito Y, Muraguchi N, Takao T, Yamamoto A, Kimura M, Tsubouchi Y, Inoue M, Yoshikawa T. [A case report of Churg-Strauss syndrome combined with various vessel diseases]. Nihon Rinsho Meneki Gakkai Kaishi 153. Naito Y, Yoshikawa T. [Oxidative stress evaluated by oxidative stress profile (OSP)]. Nippon Rinsho 2004;62 Suppl 11:525-8.
154. Naito Y, Yoshikawa T. Thiazolidinediones: a new class of drugs for the therapy of ischemia-reperfusion injury. Drugs Today (Barc) 2004;40:423-30.
155. Naito Y, Yoshida N, Yoshikawa T. [Pro-inflammatory chemokine IL-8 in gastroesophageal reflux disease]. Nippon Rinsho 2004;62:1447-53.
156. Naito Y, Uchiyama K, Kuroda M, Mizushima K, Aoi W, Kokura S, Ichikawa H, Yoshida N, Yoshikawa T. Laser capture microdissection/GeneChip analysis of gene expression in glomerular cells in diabetic db/db mice. Redox Rep 157. Naito Y, Uchiyama K, Aoi W, Hasegawa G, Nakamura N, Yoshida N, Maoka T, Takahashi J, Yoshikawa T. Prevention of diabetic nephropathy by treatment with astaxanthin in diabetic db/db mice. Biofactors 2004;20:49-59.
158. Naito Y, Takagi T, Yoshikawa T. Heme oxygenase-1: a new therapeutic target for inflammatory bowel disease. Aliment Pharmacol Ther 2004;20 Suppl 159. Naito Y, Takagi T, Uchiyama K, Kuroda M, Kokura S, Ichikawa H, Yanagisawa R, Inoue K, Takano H, Satoh M, Yoshida N, Okanoue T, Yoshikawa T.
Reduced intestinal inflammation induced by dextran sodium sulfate in interleukin-6-deficient mice. Int J Mol Med 2004;14:191-6.
160. Naito Y, Takagi T, Kuroda M, Katada K, Ichikawa H, Kokura S, Yoshida N, Okanoue T, Yoshikawa T. An orally active matrix metalloproteinase inhibitor, ONO-4817, reduces dextran sulfate sodium-induced colitis in mice. Inflamm Res 161. Naito Y, Takagi T, Ichikawa H, Tomatsuri N, Kuroda M, Isozaki Y, Katada K, Uchiyama K, Kokura S, Yoshida N, Okanoue T, Yoshikawa T. A novel potent inhibitor of inducible nitric oxide inhibitor, ONO-1714, reduces intestinal ischemia-reperfusion injury in rats. Nitric Oxide 2004;10:170-7.
162. Naito Y, Shimozawa M, Manabe H, Kuroda M, Tomatsuri N, Uchiyama K, Takagi T, Yoshida N, Yoshikawa T. Inhibitory effects of red wine extracts on endothelial-dependent adhesive interactions with monocytes induced by oxysterols.
163. Kon T, Tanigawa T, Hayamizu K, Shen M, Tsuji T, Naito Y, Yoshikawa T.
Singlet oxygen quenching activity of human serum. Redox Rep 2004;9:325-30.
164. Kokura S, Yoshida N, Imamoto E, Ueda M, Ishikawa T, Uchiyama K, Kuchide M, Naito Y, Okanoue T, Yoshikawa T. Anoxia/reoxygenation down-regulates the expression of E-cadherin in human colon cancer cell lines.
165. Kitawaki J, Koshiba H, Kitaoka Y, Teramoto M, Hasegawa G, Nakamura N, Yoshikawa T, Ohta M, Obayashi H, Honjo H. Interferon-gamma gene dinucleotide (CA) repeat and interleukin-4 promoter region (-590C/T) polymorphisms in Japanese patients with endometriosis. Hum Reprod 166. Katada K, Naito Y, Shimozawa M, Mizushima K, Kuroda M, Takagi T, Kokura S, Ichikawa H, Yoshida N, Matsui H, Yoshikawa T. Gene expression analysis following hypoxia-reoxygenation in rat gastric epithelial cells using a high-density oligonucleotide array. Redox Rep 2004;9:337-42.
167. Ito K, Shimada J, Kato D, Toda S, Takagi T, Naito Y, Yoshikawa T, Kitamura N. Protective effects of preischemic treatment with pioglitazone, a peroxisome proliferator-activated receptor-gamma ligand, on lung ischemia-reperfusion injury in rats. Eur J Cardiothorac Surg 2004;25:530-6.
168. Imamoto E, Yoshida N, Uchiyama K, Kuroda M, Kokura S, Ichikawa H, Naito Y, Tanigawa T, Yoshikawa T. Inhibitory effect of pioglitazone on expression of adhesion molecules on neutrophils and endothelial cells. Biofactors 169. Ichikawa H, Yoshida N, Takagi T, Tomatsuri N, Katada K, Isozaki Y, Uchiyama K, Naito Y, Okanoue T, Yoshikawa T. Lansoprazole ameliorates intestinal mucosal damage induced by ischemia-reperfusion in rats. World J Gastroenterol 170. Ichikawa H, Takagi T, Uchiyama K, Higashihara H, Katada K, Isozaki Y, Naito Y, Yoshida N, Yoshikawa T. Rotenone, a mitochondrial electron transport inhibitor, ameliorates ischemia-reperfusion-induced intestinal mucosal damage in 171. Hioki C, Yoshida T, Kogure A, Takakura Y, Umekawa T, Yoshioka K, Shimatsu A, Yoshikawa T. Effects of growth hormone (GH) on mRNA levels of uncoupling proteins 1, 2, and 3 in brown and white adipose tissues and skeletal muscle in obese mice. Horm Metab Res 2004;36:607-13.
172. Higashihara H, Kokura S, Imamoto E, Ueda M, Naito Y, Yoshida N, Yoshikawa T. Hypoxia-reoxygenation enhances interleukin-8 production from U937 human monocytic cells. Redox Rep 2004;9:365-9.
173. Hashimoto T, Ibi M, Matsuno K, Nakashima S, Tanigawa T, Yoshikawa T, Yabe-Nishimura C. An endogenous metabolite of dopamine, 3,4-dihydroxyphenylethanol, acts as a unique cytoprotective agent against oxidative stress-induced injury. Free Radic Biol Med 2004;36:555-64.
174. Harusato A, Naito Y, Hattori T, Yoshida N, Hagiwara A, Okanoue T, Yoshikawa T. [A case of Castleman disease arising from lesser sac]. Nippon Shokakibyo Gakkai Zasshi 2004;101:168-72.
175. Handa O, Naito Y, Takagi T, Shimozawa M, Kokura S, Yoshida N, Matsui H, Cepinskas G, Kvietys PR, Yoshikawa T. Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-kappaB. J 176. Fukui M, Kitagawa Y, Nakamura N, Kadono M, Hasegawa G, Yoshikawa T. Association between urinary albumin excretion and serum dehydroepiandrosterone sulfate concentration in male patients with type 2 diabetes: a possible link between urinary albumin excretion and cardiovascular disease.
177. Aoi W, Naito Y, Takanami Y, Kawai Y, Sakuma K, Ichikawa H, Yoshida N, Yoshikawa T. Oxidative stress and delayed-onset muscle damage after exercise.
178. Aoi W, Ichiishi E, Sakamoto N, Tsujimoto A, Tokuda H, Yoshikawa T.
Effect of exercise on hepatic gene expression in rats: a microarray analysis. Life Sci 179. Yoshikawa K, Matsumoto M, Hamanaka M, Nakagawa M. A case of manganese induced parkinsonism in hereditary haemorrhagic telangiectasia. J Neurol Neurosurg Psychiatry 2003;74:1312-4.
180. Yoshida N, Yoshikawa T. Defense mechanism of the esophageal mucosa and esophageal inflammation. J Gastroenterol 2003;38 Suppl 15:31-4.
181. Yoshida N, Ishikawa T, Ichiishi E, Yoshida Y, Hanashiro K, Kuchide M, Uchiyama K, Kokura S, Ichikawa H, Naito Y, Yamamura Y, Okanoue T, Yoshikawa T. The effect of rebamipide on Helicobacter pylori extract-mediated changes of gene expression in gastric epithelial cells. Aliment Pharmacol Ther 2003;18 Suppl 182. Yamada K, Mori S, Nakamura H, Ito H, Kizu O, Shiga K, Yoshikawa K, Makino M, Yuen S, Kubota T, Tanaka O, Nishimura T. Fiber-tracking method reveals sensorimotor pathway involvement in stroke patients. Stroke 183. Ueda M, Kokura S, Imamoto E, Naito Y, Handa O, Takagi T, Yoshida N, Yoshikawa T. Blocking of NF-kappaB activation enhances the tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer Lett 184. Tsunoda S, Takano H, Inoue K, Yoshikawa T. A case of lupus peritonitis and cystitis after ovulation induction therapy. Am J Obstet Gynecol 2003;189:888-9.
185. Omatsu T, Ichikawa H, Kawahito Y, Ashihara E, Yamamoto A, Kadoya M, Takegami T, Takanashi Y, Naito Y, Yoshida N, Sugino S, Yoshikawa T. [A case of advanced gastric cancer with bone metastases and DIC responding to oral administration of TS-1]. Gan To Kagaku Ryoho 2003;30:869-73.
186. Nakamura N, Hasegawa G, Obayashi H, Yamazaki M, Ogata M, Nakano K, Yoshikawa T, Watanabe A, Kinoshita S, Fujinami A, Ohta M, Imamura Y, Ikeda T. Increased concentration of pentosidine, an advanced glycation end product, and interleukin-6 in the vitreous of patients with proliferative diabetic retinopathy.
Diabetes Res Clin Pract 2003;61:93-101.
187. Naito Y, Takagi T, Handa O, Ishikawa T, Nakagawa S, Yamaguchi T, Yoshida N, Minami M, Kita M, Imanishi J, Yoshikawa T. Enhanced intestinal inflammation induced by dextran sulfate sodium in tumor necrosis factor-alpha deficient mice. J Gastroenterol Hepatol 2003;18:560-9.
188. Matsumoto N, Manabe H, Ochiai J, Fujita N, Takagi T, Uemura M, Naito Y, Yoshida N, Oka S, Yoshikawa T. An AT1-receptor antagonist and an angiotensin-converting enzyme inhibitor protect against hypoxia-induced apoptosis in human aortic endothelial cells through upregulation of endothelial cell nitric oxide synthase activity. Shock 2003;19:547-52.
189. Kuchide M, Tokuda H, Takayasu J, Enjo F, Ishikawa T, Ichiishi E, Naito Y, Yoshida N, Yoshikawa T, Nishino H. Cancer chemopreventive effects of oral feeding alpha-tocopherol on ultraviolet light B induced photocarcinogenesis of hairless mouse. Cancer Lett 2003;196:169-77.
190. Kokura S, Yoshikawa T. [Gene therapy for colon cancer targeting NF-kappa B]. Nippon Rinsho 2003;61 Suppl 7:515-8.
191. Kokura S, Yoshida N, Ueda M, Imamoto E, Ishikawa T, Takagi T, Naito Y, Okanoue T, Yoshikawa T. Hyperthermia enhances tumor necrosis factor alpha-induced apoptosis of a human gastric cancer cell line. Cancer Lett 192. Kimura F, Hasegawa G, Obayashi H, Adachi T, Hara H, Ohta M, Fukui M, Kitagawa Y, Park H, Nakamura N, Nakano K, Yoshikawa T. Serum extracellular superoxide dismutase in patients with type 2 diabetes: relationship to the development of micro- and macrovascular complications. Diabetes Care 193. Ishikawa T, Yoshida N, Tokuda H, Ichiishi E, Kuchide M, Kokura S, Naito Y, Toyokuni S, Nishino H, Yoshikawa T. Tumor initiating activity of Helicobacter pylori water extract on mouse skin carcinogenesis. Cancer Lett 2003;191:41-7.
194. Ishikawa T, Yoshida N, Higashihara H, Inoue M, Uchiyama K, Takagi T, Handa O, Kokura S, Naito Y, Okanoue T, Yoshikawa T. Different effects of constitutive nitric oxide synthase and heme oxygenase on pulmonary or liver metastasis of colon cancer in mice. Clin Exp Metastasis 2003;20:445-50.
195. Ichikawa H, Yoshida N, Takano H, Ishikawa T, Handa O, Takagi T, Naito Y, Murase H, Yoshikawa T. A novel vitamin E derivative (TMG) protects against gastric mucosal damage induced by ischemia and reperfusion in rats. Dig Dis Sci 196. Hasegawa G, Obayashi H, Kamiuchi K, Nakai M, Kanatsuna T, Yamaguchi M, Tanaka T, Shigeta H, Fujii M, Yoshikawa T, Nakamura N. The association between end-stage diabetic nephropathy and methylenetetrahydrofolate reductase genotype with macroangiopathy in type 2 diabetes mellitus. Exp Clin 197. Aoi W, Naito Y, Sakuma K, Kuchide M, Tokuda H, Maoka T, Toyokuni S, Oka S, Yasuhara M, Yoshikawa T. Astaxanthin limits exercise-induced skeletal and cardiac muscle damage in mice. Antioxid Redox Signal 2003;5:139-44.
198. Yoshikawa T. Introduction to serial reviews: vascular dysfunction and free radicals. Free Radic Biol Med 2002;33:425-6.
199. Yoshida N, Yoshikawa T. Effect of Helicobacter pylori-mediated inflammation on nonsteroidal anti-inflammatory drugs-induced gastric mucosal injury. Keio J Med 2002;51 Suppl 2:45-50.
200. Yoshida N, Sugimoto N, Ochiai J, Nakamura Y, Ichikawa H, Naito Y, Yoshikawa T. Role of elastase and active oxygen species in gastric mucosal injury induced by aspirin administration in Helicobacter pylori-infected Mongolian gerbils.
Aliment Pharmacol Ther 2002;16 Suppl 2:191-7.
201. Yoshida N, Sugimoto N, Hirayama F, Nakamura Y, Ichikawa H, Naito Y, Yoshikawa T. Helicobacter pylori infection potentiates aspirin induced gastric mucosal injury in Mongolian gerbils. Gut 2002;50:594-8.
202. Yoshida N, Murase H, Kunieda T, Toyokuni S, Tanaka T, Terao J, Naito Y, Tanigawa T, Yoshikawa T. Inhibitory effect of a novel water-soluble vitamin E derivative on atherosclerosis in rabbits. Atherosclerosis 2002;162:111-7.
203. Uemura M, Manabe H, Yoshida N, Fujita N, Ochiai J, Matsumoto N, Takagi T, Naito Y, Yoshikawa T. Alpha-tocopherol prevents apoptosis of vascular endothelial cells via a mechanism exceeding that of mere antioxidation. Eur J 204. Uchiyama K, Naito Y, Hasegawa G, Nakamura N, Takahashi J, Yoshikawa T. Astaxanthin protects beta-cells against glucose toxicity in diabetic db/db mice.
205. Tegoshi H, Hasegawa G, Obayashi H, Nakano K, Kitagawa Y, Fukui M, Matsuo S, Deguchi M, Ohta M, Nishimura M, Nakamura N, Yoshikawa T.
Polymorphisms of interferon-gamma gene CA-repeat and interleukin-10 promoter region (-592A/C) in Japanese type I diabetes. Hum Immunol 2002;63:121-8.
206. Takagi T, Naito Y, Tomatsuri N, Handa O, Ichikawa H, Yoshida N, Yoshikawa T. Pioglitazone, a PPAR-gamma ligand, provides protection from dextran sulfate sodium-induced colitis in mice in association with inhibition of the NF-kappaB-cytokine cascade. Redox Rep 2002;7:283-9.
207. Sakamoto S, Okanoue T, Itoh Y, Nakagawa Y, Nakamura H, Morita A, Daimon Y, Sakamoto K, Yoshida N, Yoshikawa T, Kashima K. Involvement of Kupffer cells in the interaction between neutrophils and sinusoidal endothelial cells 208. Ochiai J, Takano H, Ichikawa H, Naito Y, Yoshida N, Yanagisawa R, Yoshino S, Murase H, Yoshikawa T. A novel water-soluble vitamin E derivative, 2-(alpha-D-glucopyranosyl)methyl-2,5,7,8-tetramethylchroman-6-ol, protects against acute lung injury and mortality in endotoxemic rats. Shock 2002;18:580-4.
209. Nakata Y, Shiga K, Yoshikawa K, Mizuno T, Mori S, Yamada K, Nakajima K. Subclinical brain hemorrhages in Alzheimer's disease: evaluation by magnetic resonance T2*-weighted images. Ann N Y Acad Sci 2002;977:169-72.
210. Naito Y, Yoshikawa T. [Reactive oxygen species and free radical reactions are involved in the pathogenesis of non-steroidal anti-inflammatory drugs-induced gastric mucosal injury]. Nippon Rinsho 2002;60 Suppl 2:211-6.
211. Naito Y, Yoshikawa T. Molecular and cellular mechanisms involved in Helicobacter pylori-induced inflammation and oxidative stress. Free Radic Biol 212. Naito Y, Takagi T, Uchiyama K, Handa O, Tomatsuri N, Imamoto E, Kokura S, Ichikawa H, Yoshida N, Yoshikawa T. Suppression of intestinal ischemia-reperfusion injury by a specific peroxisome proliferator-activated receptor-gamma ligand, pioglitazone, in rats. Redox Rep 2002;7:294-9.
213. Naito Y, Takagi T, Ishikawa T, Handa O, Matsumoto N, Yagi N, Matsuyama K, Yoshida N, Yoshikawa T, Kotake Y.
alpha-Phenyl-N-tert-butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice. Antioxid Redox Signal 2002;4:195-206.
214. Naito Y, Handa O, Takagi T, Ishikawa T, Imamoto E, Nakagawa S, Yamaguchi T, Yoshida N, Matsui H, Yoshikawa T. Ubiquitin-proteasome inhibitor enhances tumour necrosis factor-alpha-induced apoptosis in rat gastric epithelial cells. Aliment Pharmacol Ther 2002;16 Suppl 2:59-66.
215. Murotani Y, Kuroda J, Kimura S, Terao K, Fukiya E, Ozawa M, Kobayashi Y, Yoshikawa T. Non-myeloablative haematopoietic stem cell transplantation for severe aplastic anaemia with various complications. Clin Lab 216. Kuroda J, Kimura S, Kobayashi Y, Wada K, Uoshima N, Yoshikawa T.
Unusual myelodysplastic syndrome with the initial presentation mimicking idiopathic thrombocytopenic purpura. Acta Haematol 2002;108:139-43.
217. Kokura S, Yoshida N, Yoshikawa T. Anoxia/reoxygenation-induced leukocyte-endothelial cell interactions. Free Radic Biol Med 2002;33:427-32.
218. Kokura S, Nakagawa S, Hara T, Boku Y, Naito Y, Yoshida N, Yoshikawa T. Enhancement of lipid peroxidation and of the antitumor effect of hyperthermia upon combination with oral eicosapentaenoic acid. Cancer Lett 2002;185:139-44.
219. Kogure A, Sakane N, Takakura Y, Umekawa T, Yoshioka K, Nishino H, Yamamoto T, Kawada T, Yoshikawa T, Yoshida T. Effects of caffeine on the uncoupling protein family in obese yellow KK mice. Clin Exp Pharmacol Physiol 220. Kitawaki J, Obayashi H, Ohta M, Kado N, Ishihara H, Koshiba H, Kusuki I, Tsukamoto K, Hasegawa G, Nakamura N, Yoshikawa T, Honjo H. Genetic contribution of the interleukin-10 promoter polymorphism in endometriosis susceptibility. Am J Reprod Immunol 2002;47:12-8.
221. Kitamura A, Hasegawa G, Obayashi H, Kamiuchi K, Ishii M, Yano M, Tanaka T, Yamaguchi M, Shigeta H, Ogata M, Nakamura N, Yoshikawa T.
Interleukin-6 polymorphism (-634C/G) in the promotor region and the progression of diabetic nephropathy in type 2 diabetes. Diabet Med 2002;19:1000-5.
222. Kawata E, Kuroda J, Kimura S, Kamitsuji Y, Kobayashi Y, Yoshikawa T.
Aplastic anemia evolving into overt myelodysplastic syndrome/acute myeloid leukemia with t(3;5)(p25;q31). Cancer Genet Cytogenet 2002;137:91-4.
223. Kashiwagi N, Nakano M, Saniabadi AR, Adachi M, Yoshikawa T.
Anti-inflammatory effect of granulocyte and monocyte adsorption apheresis in a rabbit model of immune arthritis. Inflammation 2002;26:199-205.
224. Kamiuchi K, Hasegawa G, Obayashi H, Kitamura A, Ishii M, Yano M, Kanatsuna T, Yoshikawa T, Nakamura N. Intercellular adhesion molecule-1 (ICAM-1) polymorphism is associated with diabetic retinopathy in Type 2 diabetes 225. Kamiuchi K, Hasegawa G, Obayashi H, Kitamura A, Ishii M, Yano M, Kanatsuna T, Yoshikawa T, Nakamura N. Leukocyte-endothelial cell adhesion molecule 1 (LECAM-1) polymorphism is associated with diabetic nephropathy in type 2 diabetes mellitus. J Diabetes Complications 2002;16:333-7.
226. Kado N, Kitawaki J, Obayashi H, Ishihara H, Koshiba H, Kusuki I, Tsukamoto K, Hasegawa G, Nakamura N, Yoshikawa T, Honjo H. Association of the CYP17 gene and CYP19 gene polymorphisms with risk of endometriosis in Japanese women. Hum Reprod 2002;17:897-902.
227. Ichikawa H, Naito Y, Takagi T, Tomatsuri N, Yoshida N, Yoshikawa T. A specific peroxisome proliferator-activated receptor-gamma (PPAR-gamma) ligand, pioglitazone, ameliorates gastric mucosal damage induced by ischemia and reperfusion in rats. Redox Rep 2002;7:343-6.
228. Handa O, Yoshida N, Tanaka Y, Ueda M, Ishikawa T, Takagi T, Matsumoto N, Naito Y, Yoshikawa T. Inhibitory effect of polaprezinc on the inflammatory response to Helicobacter pylori. Can J Gastroenterol 2002;16:785-9.
229. Handa O, Naito Y, Takagi T, Ishikawa T, Ueda M, Matsumoto N, Kokura S, Ichikawa H, Yoshida N, Shimoi K, Yoshikawa T. Inhibitory effects of catechins on neutrophil-dependent gastric inflammation. Redox Rep 2002;7:324-8.
230. Yoshikawa T, Uchiyama K, Naito Y, Yoshida N. [Gastrointestinal manifestations in collagen disease]. Nippon Shokakibyo Gakkai Zasshi 231. Yoshikawa T, Naito Y. The Role of Neutrophils and Inflammation in Gastric Mucosal Injury. Free Radic Res 2001;33:785-794.
232. Yoshida N, Yamaguchi T, Nakagawa S, Nakamura Y, Naito Y, Yoshikawa T. Role of P-selectin and intercellular adhesion molecule-1 in TNB-induced colitis in rats. Digestion 2001;63 Suppl 1:81-6.
233. Naito Y, Yoshikawa T, Yagi N, Matsuyama K, Yoshida N, Seto K, Yoneta T. Effects of polaprezinc on lipid peroxidation, neutrophil accumulation, and TNF-alpha expression in rats with aspirin-induced gastric mucosal injury. Dig Dis 234. Naito Y, Takagi T, Matsuyama K, Yoshida N, Yoshikawa T. Pioglitazone, a specific PPAR-gamma ligand, inhibits aspirin-induced gastric mucosal injury in rats. Aliment Pharmacol Ther 2001;15:865-73.
235. Naito Y, Takagi T, Ishikawa T, Handa O, Matsumoto N, Yagi N, Matsuyama K, Yoshida N, Yoshikawa T. The inducible nitric oxide synthase inhibitor ONO-1714 blunts dextran sulfate sodium colitis in mice. Eur J Pharmacol 236. Naito Y, Takagi T, Handa O, Ishikawa T, Matsumoto N, Yoshida N, Kato H, Ando T, Takemura T, Itani K, Hisatomi H, Tsuchihashi Y, Yoshikawa T.
Telomerase activity and expression of telomerase RNA component and catalytic subunits in precancerous and cancerous colorectal lesions. Tumour Biol 237. Kuroda J, Omoto A, Fujiki H, Okugawa K, Tamai H, Yamagishi H, Kobayashi Y, Yoshikawa T. Primary hepatic Burkitt's lymphoma with chronic hepatitis C. Acta Haematol 2001;105:237-40.
238. Inoue K, Kawahito Y, Tsubouchi Y, Kohno M, Yoshimura R, Yoshikawa T, Sano H. Expression of peroxisome proliferator-activated receptor gamma in renal cell carcinoma and growth inhibition by its agonists. Biochem Biophys Res 239. Higashihara H, Yoshida N, Yoshikawa T. [Hyperthermia for hepatocellular carcinoma]. Nippon Rinsho 2001;59 Suppl 6:650-3.
240. Yoshikawa T, Yoshida N. Vitamin E and leukocyte-endothelial cell interactions. Antioxid Redox Signal 2000;2:821-5.
241. Yoshikawa T, Tanigawa M, Tanigawa T, Imai A, Hongo H, Kondo M.
Enhancement of nitric oxide generation by low frequency electromagnetic field.
242. Yoshikawa T, Naito Y. The role of neutrophils and inflammation in gastric mucosal injury. Free Radic Res 2000;33:785-94.
243. Yoshikawa T, Mori A. Preface. Pathophysiology 2000;7:81.
244. Yoshida N, Yoshikawa T, Tanaka Y, Fujita N, Kassai K, Naito Y, Kondo M. A new mechanism for anti-inflammatory actions of proton pump inhibitors--inhibitory effects on neutrophil-endothelial cell interactions. Aliment Pharmacol Ther 2000;14 Suppl 1:74-81.
245. Yoshida N, Manabe H, Terasawa Y, Nishimura H, Enjo F, Nishino H, Yoshikawa T. Inhibitory effects of vitamin E on endothelial-dependent adhesive interactions with leukocytes induced by oxidized low density lipoprotein. Biofactors 246. Terasawa Y, Manabe H, Yoshida N, Uemura M, Sugimoto N, Naito Y, Yoshikawa T, Kondo M. Alpha-tocopherol protects against monocyte Mac-1 (CD11b/CD18) expression and Mac-1-dependent adhesion to endothelial cells induced by oxidized low-density lipoprotein. Biofactors 2000;11:221-33.
247. Sugimoto N, Yoshida N, Yoshikawa T, Nakamuara Y, Ichikawa H, Naito Y, Kondo M. Effect of vitamin E on aspirin-induced gastric mucosal injury in rats. Dig 248. Nakamura N, Obayashi H, Fujii M, Fukui M, Yoshimori K, Ogata M, Hasegawa G, Shigeta H, Kitagawa Y, Yoshikawa T, Kondo M, Ohta M, Nishimura M, Nishinaka T, Nishimura CY. Induction of aldose reductase in cultured human microvascular endothelial cells by advanced glycation end products. Free Radic Biol 249. Naito Y, Yoshikawa T, Boku Y, Fujii T, Masui Y, Tanaka Y, Fujita N, Yoshida N, Kondo M. Protective role of intracellular glutathione against nitric oxide-induced necrosis in rat gastric mucosal cells. Aliment Pharmacol Ther 250. Ichiishi E, Yoshikawa T, Kogawa T, Yoshida N, Kondo M. Possible paracrine growth of adenocarcinoma of the stomach induced by granulocyte colony stimulating factor produced by squamous cell carcinoma of the oesophagus. Gut 251. Fujita N, Manabe H, Yoshida N, Matsumoto N, Ochiai J, Masui Y, Uemura M, Naito Y, Yoshikawa T. Inhibition of angiotensin-converting enzyme protects endothelial cell against hypoxia/reoxygenation injury. Biofactors 252. Asai K, Kato H, Hirose K, Akaogi K, Kimura S, Mukai S, Inoue M, Yamamura Y, Sano H, Sugino S, Yoshikawa T, Kondo M. PSK and OK-432-induced immunomodulation of inducible nitric oxide (NO) synthase gene expression in mouse peritoneal polymorphonuclear leukocytes and NO-mediated cytotoxicity. Immunopharmacol Immunotoxicol 2000;22:221-35.
253. Arimoto T, Ichinose T, Yoshikawa T, Shibamoto T. Effect of the natural antioxidant 2"-O-glycosylisovitexin on superoxide and hydroxyl radical generation.
254. Yoshikawa T, Naito Y, Kondo M. Ginkgo biloba leaf extract: review of biological actions and clinical applications. Antioxid Redox Signal 1999;1:469-80.
255. Yoshida N, Yoshikawa T, Yamaguchi T, Naito Y, Tanigawa T, Murase H, Kondo M. A novel water-soluble vitamin E derivative protects against experimental colitis in rats. Antioxid Redox Signal 1999;1:555-62.
256. Yoshida N, Yoshikawa T, Nakagawa S, Sakamoto K, Nakamura Y, Naito Y, Kondo M. Effect of shear stress and a stable prostaglandin I2 analogue on adhesive interactions of colon cancer cells and endothelial cells. Clin Exp Immunol 257. Yoshida N, Yoshikawa T, Nakagawa S, Miyajima T, Nakamura Y, Naito Y, Tanigawa T, Kondo M. Characteristics of the production of active oxygen species from adherent and non-adherent neutrophils. Biofactors 1999;9:19-26.
258. Yoshida N, Yoshikawa T, Manabe H, Terasawa Y, Kondo M, Noguchi N, Niki E. Vitamin E protects against polymorphonuclear leukocyte-dependent adhesion to endothelial cells. J Leukoc Biol 1999;65:757-63.
259. Toyama K, Yoshikawa K, Yoshida Y, Kondo Y, Tomita S, Takanashi Y, Ejima Y, Yoshizawa S. A new method for magnetoencephalography: a three-dimensional magnetometer-spatial filter system. Neuroscience 260. Naito Y, Yoshikawa T, Matsuyama K, Yagi N, Kasai K, Sugimoto N, Masui Y, Yoshida N, Kondo M. Effect of vitamin E in gastric mucosal injury induced by ischaemia-reperfusion in nitric oxide-depleted rats. Aliment Pharmacol 261. Kassai K, Yoshikawa T, Yoshida N, Hashiramoto A, Kondo M, Murase H.
Helicobacter pylori water extract induces interleukin-8 production by gastric epithelial cells. Dig Dis Sci 1999;44:237-42.
262. Ishikawa T, Kobayashi Y, Omoto A, Adachi Y, Nakagawa S, Kaneko T, Nishida K, Miyamoto Y, Chimori Y, Yoshikawa T, Kondo M. Calcification in untreated non-Hodgkin's lymphoma of the jejunum. Acta Haematol 1999;102:185-9.
263. Imamoto E, Naito Y, Minami M, Boku Y, Inuma S, Masuyama M, Taniguchi H, Yoshikawa T, Kondo M. [A case of advanced hepatocellular carcinoma treated by repeated arterial infusion chemotherapy of 5-FU, LV, CDDP with an implanted reservoir]. Nippon Shokakibyo Gakkai Zasshi 1999;96:675-9.
264. Hongo H, Takano H, Imai A, Yamaguchi T, Boku Y, Fujii T, Naito Y, Yoshida N, Yoshikawa T, Kondo M. Pancreatic phospholipase A2 induces bacterial translocation in rats. Immunopharmacol Immunotoxicol 1999;21:717-26.
265. Ding Y, Matsukawa Y, OhtaniFujita N, Kato D, Dao S, Fujii T, Naito Y, Yoshikawa T, Sakai T, Rosenthal GA. Growth inhibition of A549 human lung adenocarcinoma cells by L-canavanine is associated with p21/WAF1 induction. Jpn 266. Capodicasa E, De Bellis F, Pelli MA. Effect of lansoprazole on human leukocyte function. Immunopharmacol Immunotoxicol 1999;21:357-77.
267. Arimoto T, Yoshikawa T, Takano H, Kohno M. Generation of reactive oxygen species and 8-hydroxy-2'-deoxyguanosine formation from diesel exhaust particle components in L1210 cells. Jpn J Pharmacol 1999;80:49-54.
268. Yoshikawa T, Yoshida N, Sugimoto N, Kondo M. [Neutrophil-endothelial cell interactions in gastrointestinal diseases]. Nippon Rinsho 1998;56:2240-6.
269. Yoshikawa T, Yoshida N, Manabe H, Terasawa Y, Takemura T, Kondo M.
alpha-Tocopherol protects against expression of adhesion molecules on neutrophils and endothelial cells. Biofactors 1998;7:15-9.
270. Yoshikawa T, Takano H, Kondo M. Role of nitric oxide and reactive oxygen species in endotoxin shock. Prog Clin Biol Res 1998;397:357-63.
271. Naito Y, Yoshikawa T, Yoshida N, Kondo M. Role of oxygen radical and lipid peroxidation in indomethacin-induced gastric mucosal injury. Dig Dis Sci 272. Naito Y, Yoshikawa T, Matsuyama K, Yagi N, Arai M, Nakamura Y, Kaneko T, Yoshida N, Kondo M. Neutrophils, lipid peroxidation, and nitric oxide in gastric reperfusion injury in rats. Free Radic Biol Med 1998;24:494-502.
273. Naito Y, Yoshikawa T, Iinuma S, Yagi N, Matsuyama K, Boku Y, Fujii T, Yoshida N, Kondo M, Sasaki S. Rebamipide protects against indomethacin-induced gastric mucosal injury in healthy volunteers in a double-blind, placebo-controlled study. Dig. Dis. Sci. 1998;43:83S-89S.
274. Morita Y, Yoshikawa T, Takeda S, Matsuyama K, Takahashi S, Yoshida N, Clemens MG, Kondo M. Involvement of lipid peroxidation in free fatty acid-induced isolated rat pancreatic acinar cell injury. Pancreas 1998;17:383-9.
275. Makino M, Takanashi Y, Iwamoto K, Yoshikawa K, Ohshima H, Nakajima K, Hayashi K, Hayashi R, Endo K. [Auditory evoked magnetic fields in patients of pure word deafness]. No To Shinkei 1998;50:51-5.
276. Iinuma S, Yoshikawa T, Yoshida N, Naito Y, Kondo M. Role of active oxygen species and lipid peroxidation in mepirizole-induced duodenal ulcers in rats.
277. Yoshikawa T, Yamaguchi T, Yoshida N, Yamamoto H, Kitazumi S, Takahashi S, Naito Y, Kondo M. Effect of Z-103 on TNB-induced colitis in rats.
278. Yoshikawa T, Takano H, Yamamoto H, Nakahashi Y, Yamaguchi T, Arimoto T, Kondo M. Role of superoxide and nitric oxide in platelet-activating factor-induced acute lung injury, hypotension, and mortality in rats. Crit Care Med 279. Yoshikawa T, Naito Y, Masui K, Fujii T, Boku Y, Nakagawa S, Yoshida N, Kondo M. Free radical-scavenging activity of Crassostera gigas extract (JCOE).
280. Yoshikawa T, Minamiyama Y, Ichikawa H, Takahashi S, Naito Y, Kondo M. Role of lipid peroxidation and antioxidants in gastric mucosal injury induced by the hypoxanthine-xanthine oxidase system in rats. Free Radic Biol Med 281. Yoshikawa T, Kondo M. [Measurement of reactive oxygen species generated from neutrophils]. Nippon Rinsho 1997;55 Suppl 1:210-5.
282. Yoshikawa K, Iwamoto K, Sugimoto E, Takanashi Y, Nakajima K. [A case of porencephaly with mirror movements: pathophysiological investigation by using long-latency long-loop reflex and dipole tracing method]. Rinsho Shinkeigaku 283. Yoshida N, Yoshikawa T, Nakamura Y, Takenaka S, Sakamoto K, Manabe H, Nakagawa S, Kondo M. Methylprednisolone inhibits neutrophil-endothelial cell interactions induced by interleukin-1beta under flow conditions. Life Sci 284. Tenjin H, Yasukochi K, Nakahara Y, Higuchi T, Naruse S, Ueda S, Horikawa Y, Furuya S, Yoshikawa K. Preoperative detection of the composition of atherosclerotic plaque in the carotid artery using ultrasonography and magnetic resonance imaging. Neurol Med Chir (Tokyo) 1997;37:505-10; discussion 510-1.
285. Takano H, Yoshikawa T, Yamaguchi T, Hongo H, Fujii T, Boku Y, Yoshida N, Yamamoto H, Nakahashi Y, Yanagisawa R, Kondo M. Effects of aminoguanidine on systemic inflammatory response syndrome induced by platelet activating factor and by lipopolysaccharide in rats. Eur J Pharmacol 1997;323:107-10.
286. Sha S, Minakuchi K, Higaki N, Sato K, Ohtsuki K, Kurata A, Yoshikawa H, Kotaru M, Masumura T, Ichihara K, Tanaka K. Purification and characterization of glutaredoxin (thioltransferase) from rice (Oryza sativa L.). J Biochem (Tokyo) 287. Sakamoto S, Okanoue T, Itoh Y, Sakamoto K, Nishioji K, Nakagawa Y, Yoshida N, Yoshikawa T, Kashima K. Intercellular adhesion molecule-1 and CD18 are involved in neutrophil adhesion and its cytotoxicity to cultured sinusoidal endothelial cells in rats. Hepatology 1997;26:658-63.
288. Naito Y, Yoshikawa T, Matsuyama K, Yagi N, Nakamura Y, Nishimura S, Kaneko T, Yoshida N, Kondo M. Effect of the histamine H2-receptor antagonist (+/-)-(E)-1-[2-hydroxy-2-(4-hydroxyphenyl)ethyl]-3'-[2-[[[5-methylamino ) methyl-2-furyl] methyl]thio]ethyl]-2"-(methylsulfonyl)guanidine on acute gastric mucosal injury in rats and its free-radical scavenging activities.
Arzneimittelforschung 1997;47:845-8.
289. Naito Y, Yoshikawa T, Fujii T, Boku Y, Yagi N, Dao S, Yoshida N, Kondo M, Matsui H, Ohtani-Fujita N, Sakai T. Monochloramine-induced cell growth inhibition and apoptosis in a rat gastric mucosal cell line. J Clin Gastroenterol 290. Kokura S, Yoshikawa T, Naito Y, Ichikawa H, Takano H, Takahashi S, Tomii T, Yoshida N, Kondo M. Effects of rebamipide, a novel anti-ulcer agent, on gastric mucosal injury induced by platelet-activating factor in rats. Dig Dis Sci 291. Kokura S, Yoshikawa T, Kaneko T, Iinuma S, Nishimura S, Matsuyama K, Naito Y, Yoshida N, Kondo M. Efficacy of hyperthermia and polyunsaturated fatty acids on experimental carcinoma. Cancer Res 1997;57:2200-2.
292. Yoshikawa T, Naito Y, Yoshida N. [Pathogenesis and therapy of non-steroidal anti-inflammatory drug (NSAID)-induced gastric mucosal injury].
Nippon Seikeigeka Gakkai Zasshi 1996;70:269-73.
293. Yoshida N, Yoshikawa T, Iinuma S, Arai M, Takenaka S, Sakamoto K, Miyajima T, Nakamura Y, Yagi N, Naito Y, Mukai F, Kondo M. Rebamipide protects against activation of neutrophils by Helicobacter pylori. Dig Dis Sci 294. Naito Y, Yoshikawa T, Iinuma S, Miyazaki R, Yagi N, Yoshida N, Osumi T, Hirao Y, Kondo M. Local gastric and serum concentrations of rebamipide following oral administration to patients with chronic gastritis.
Arzneimittelforschung 1996;46:698-700.
295. Kokura S, Yoshikawa T, Tainaka K, Kaneko T, Iinuma S, Nishimura S, Matuyama K, Kondo M. Anti-tumor effects of hyperthermia plus granulocyte colony-stimulating factor. Jpn J Cancer Res 1996;87:862-6.
296. Arimoto T, Yoshikawa T, Komori Y, Kumagai Y. Inhibition of constitutive nitric oxide synthase by benexate. Life Sci 1996;59:953-9.
297. Yoshikawa T, Takano H, Yoshida N, Kondo M. Simultaneous intraperitoneal administration of OK-432 and serum enhances superoxide generation from migrated polymorphonuclear leukocytes, with special emphasis on the role of complements. Immunopharmacol Immunotoxicol 1995;17:265-82.
298. Yoshikawa T, Kokura S, Tainaka K, Naito Y, Kondo M. A novel cancer therapy based on oxygen radicals. Cancer Res 1995;55:1617-20.
299. Yoshida N, Yoshikawa T, Nakamura Y, Arai M, Matsuyama K, Iinuma S, Yagi N, Naito Y, Miyasaka M, Kondo M. Role of neutrophil-mediated inflammation in aspirin-induced gastric mucosal injury. Dig Dis Sci 1995;40:2300-4.
300. Yoshida N, Yoshikawa T, Nakamura Y, Arai M, Matsuyama K, Iinuma S, Nishimura S, Kondo M. Role of neutrophil-endothelial cell interactions in gastric mucosal injury induced by aspirin. J Clin Gastroenterol 1995;21 Suppl 1:S73-7.
301. Suzuki M, Nakamura M, Mori M, Miura S, Tsuchiya M, Ishii H.
Lansoprazole inhibits oxygen-derived free radical production from neutrophils activated by Helicobacter pylori. J Clin Gastroenterol 1995;20 Suppl 2:S93-6.
302. Naito Y, Yoshikawa T, Yoneta T, Yagi N, Matsuyama K, Arai M, Tanigawa T, Kondo M. A new gastric ulcer model in rats produced by ferrous iron and ascorbic acid injection. Digestion 1995;56:472-8.
303. Naito Y, Yoshikawa T, Tanigawa T, Sakurai K, Yamasaki K, Uchida M, Kondo M. Hydroxyl radical scavenging by rebamipide and related compounds: electron paramagnetic resonance study. Free Radic Biol Med 1995;18:117-23.
304. Naito Y, Yoshikawa T, Matsuyama K, Yagi N, Arai M, Nakamura Y, Nishimura S, Yoshida N, Kondo M. Effects of oxygen radical scavengers on the quality of gastric ulcer healing in rats. J Clin Gastroenterol 1995;21 Suppl 1:S82-6.
305. Naito Y, Yoshikawa T, Matsuyama K, Yagi N, Arai M, Nakamura Y, Kaneko T, Yoshida N, Kondo M. Effect of a novel histamine H2 receptor antagonist, IT-066, on acute gastric injury induced by ischemia-reperfusion in rats, and its antioxidative properties. Eur J Pharmacol 1995;294:47-54.
306. Naito Y, Yoshikawa T, Matsuyama K, Nishimura S, Yagi N, Kondo M.
Effects of free radical scavengers on indomethacin-induced aggravation of gastric ulcer in rats. Dig Dis Sci 1995;40:2019-21.
307. Matsuki M, Hashimoto K, Yoshikawa K, Yasuno H, Yamanishi K.
Epidermolysis bullosa simplex (Weber-Cockayne) associated with a novel missense mutation of Asp328 to Val in Linker 12 domain of keratin 5. Hum Mol Genet 308. Kondo M, Yoshikawa T, Takano H. [Free radical and allergy]. Arerugi 309. Kondo M, Itani K, Yoshikawa T, Tanaka Y, Watanabe N, Hiraoka M, Noguchi M, Miura K. [A prospective randomized clinical trial comparing intra-arterial chemotherapy alone and when combined with hyperthermia for metastatic liver cancer]. Gan To Kagaku Ryoho 1995;22:1807-11.
310. Fujita N, Yoshikawa T, Uemura M, Tsukuda C, Matsumoto N, Shimada M, Arai M, Yagi N, Naito Y, Kondo M. [A case of juvenile hepatocellular carcinoma arising from normal liver]. Nippon Shokakibyo Gakkai Zasshi 1995;92:1092-7.
311. Yoshikawa T, Takano H, Takahashi S, Ichikawa H, Kondo M. Changes in tissue antioxidant enzyme activities and lipid peroxides in endotoxin-induced multiple organ failure. Circ Shock 1994;42:53-8.
312. Yoshikawa T, Naito Y. Reperfusion injury in gastric mucosa. Ann N Y 313. Yoshikawa T, Minamiyama Y, Naito Y, Kondo M. Antioxidant properties of bromocriptine, a dopamine agonist. J Neurochem 1994;62:1034-8.
314. Yoshikawa T, Kokura S, Oyamada H, Iinuma S, Nishimura S, Kaneko T, Naito Y, Kondo M. Antitumor effect of ischemia-reperfusion injury induced by transient embolization. Cancer Res 1994;54:5033-5.
315. Tanigawa T, Yoshikawa T, Takahashi S, Naito Y, Kondo M. Spin trapping of superoxide in aqueous solutions of fresh and aged cigarette smoke. Free Radic 316. Minamiyama Y, Yoshikawa T, Tanigawa T, Takahashi S, Naito Y, Ichikawa H, Kondo M. Antioxidative effects of a processed grain food. J Nutr Sci 317. Arai M, Yoshikawa T, Kondo M. [Enterocolitis]. Nippon Rinsho 318. Yoshikawa T, Nakamura S, Takahashi S, Naito Y, Kondo M. Effect of sofalcone on gastric mucosal injury induced by ischemia-reperfusion and its antioxidant properties. J Clin Gastroenterol 1993;17 Suppl 1:S111-5.
319. Yoshikawa T, Naito Y, Tanigawa T, Kondo M. Free radical scavenging activity of the novel anti-ulcer agent rebamipide studied by electron spin resonance.
Arzneimittelforschung 1993;43:363-6.
320. Yoshikawa T, Naito Y, Nakamura S, Nishimura S, Kaneko T, Iinuma S, Takahashi S, Kondo M, Yamasaki K. Effect of rebamipide on lipid peroxidation and gastric mucosal injury induced by indometacin in rats. Arzneimittelforschung 321. Yoshikawa T, Naito Y, Kondo M. Antioxidant therapy in digestive diseases. J Nutr Sci Vitaminol (Tokyo) 1993;39 Suppl:S35-41.
322. Yoshikawa T, Naito Y, Kishi A, Tomii T, Kaneko T, Iinuma S, Ichikawa H, Yasuda M, Takahashi S, Kondo M. Role of active oxygen, lipid peroxidation, and antioxidants in the pathogenesis of gastric mucosal injury induced by indomethacin 323. Yoshikawa T, Kokura S, Tainaka K, Itani K, Oyamada H, Kaneko T, Naito Y, Kondo M. The role of active oxygen species and lipid peroxidation in the antitumor effect of hyperthermia. Cancer Res 1993;53:2326-9.
324. Yoshikawa T, Itani K, Kokura S, Oyamada H, Kondo M. [Effect of intra-arterial chemotherapy combined with degradable starch microspheres against liver cancer--a study by experimental VX2 liver tumor model]. Gan To Kagaku 325. Yoshikawa T. Free radicals and their scavengers in Parkinson's disease.
326. Tanigawa T, Yoshikawa T, Minamiyama Y, Takahashi S, Ando T, Naito Y, Morita Y, Kondo M. Detection of free radicals in the blood of animals using extracorporeal circulation. Free Radic Res Commun 1993;19 Suppl 1:S171-6.
327. Takahashi S, Yoshikawa T, Naito Y, Minamiyama Y, Tanigawa T, Kondo M. Antioxidant properties of antiulcer Kampo medicines. Free Radic Res Commun 328. Naito Y, Yoshikawa T, Kaneko T, Iinuma S, Nishimura S, Takahashi S, Kondo M. Role of oxygen radicals in indomethacin-induced gastric mucosal microvascular injury in rats. J Clin Gastroenterol 1993;17 Suppl 1:S99-103.
329. Yoshikawa T, Takano H, Naito Y, Oyamada H, Ueda S, Kondo M.
Augmentative effects of tumor necrosis factor-alpha (human, natural type) on polymorphonuclear leukocyte-derived superoxide generation induced by various stimulants. Int J Immunopharmacol 1992;14:1391-8.
330. Yoshikawa T, Takahashi S, Naito Y, Ueda S, Tanigawa T, Yoshida N, Kondo M. Effects of a platelet-activating factor antagonist, CV-6209, on gastric mucosal lesions induced by ischemia-reperfusion. Lipids 1992;27:1058-60.
331. Yoshikawa T, Takahashi S, Naito Y, Kondo M. Antioxidants in gastric mucosal injury. J Nutr Sci Vitaminol (Tokyo) 1992;Spec No:556-9.
332. Yoshikawa T, Takahashi S, Kondo M. Possible role of free radicals in the chronic inflammation of the gut. Exs 1992;62:353-8.
333. Yoshikawa T, Naito Y, Ueda S, Ichikawa H, Takahashi S, Yasuda M, Kondo M. Ischemia-reperfusion injury and free radical involvement in gastric mucosal disorders. Adv Exp Med Biol 1992;316:231-8.
334. Yoshikawa T, Ichikawa H, Naito Y, Kondo M. Role of leukotrienes in gastric mucosal injury induced by ischemia-reperfusion in rats. J Clin Gastroenterol 335. Oda T, Nakai I, Mituo M, Yamagishi H, Oka T, Yoshikawa T. Role of oxygen radicals and synergistic effect of superoxide dismutase and catalase on ischemia-reperfusion injury of the rat pancreas. Transplant Proc 1992;24:797-8.
336. Naito Y, Yoshikawa T, Ando T, Kishi A, Ueda S, Oyamada H, Kondo M.
Changes in superoxide dismutase activity in the gastric mucosa of peptic ulcer patients. J Clin Gastroenterol 1992;14 Suppl 1:S131-4.
337. Kokura S, Yoshikawa T, Kaneko T, Iinuma S, Oyamada H, Tainaka K, Itani K, Kondo M. [Role of polymorphonuclear leukocytes (PMN) and active oxygen species in hyperthermia--antitumor effect of hyperthermia combined with rhG-CSF]. Gan To Kagaku Ryoho 1992;19:1655-8.
338. Kawai T, Wada Y, Kawachi H, Ohga K, Oka T, Yasuda M, Yoshikawa T.
[Metabolism of Ca2+ in myocytes and peroxidation products in ischemia-reperfusion injury under extracorporeal circulation]. Nippon Kyobu Geka 339. Kaneko T, Yoshikawa T, Kokura S, Nishimura S, Naito Y, Takemura T, Tainaka K, Kondo M. [Role of polymorphonuclear leukocytes (PMN) and active oxygen species in hyperthermia--enhancing effect of G-CSF on superoxide generation from PMN]. Gan To Kagaku Ryoho 1992;19:1659-62.
340. Ichitani Y, Okaichi H, Yoshikawa T, Ibata Y. Learning behaviour in chronic vitamin E-deficient and -supplemented rats: radial arm maze learning and passive avoidance response. Behav Brain Res 1992;51:157-64.
341. Fukui M, Kogawa T, Tawara Y, Yamamoto H, Matsuyama K, Tsujigiwa M, Yoshikawa T, Sugino S, Kondo M. [A case report of huge liver cyst with edema of lower extremities]. Nippon Shokakibyo Gakkai Zasshi 1992;89:2798-803.
342. Yoshikawa T, Yasuda M, Ueda S, Naito Y, Tanigawa T, Oyamada H, Kondo M. Vitamin E in gastric mucosal injury induced by ischemia-reperfusion. Am 343. Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Yasuda M, Ueda S, Oyamada H, Kondo M. Effect of zinc-carnosine chelate compound (Z-103), a novel antioxidant, on acute gastric mucosal injury induced by ischemia-reperfusion in rats.
Free Radic Res Commun 1991;14:289-96.
344. Yoshikawa T, Naito Y, Tanigawa T, Yoneta T, Kondo M. The antioxidant properties of a novel zinc-carnosine chelate compound, N-(3-aminopropionyl)-L-histidinato zinc. Biochim Biophys Acta 1991;1115:15-22.
345. Takahashi S, Yoshikawa T, Naito Y, Tanigawa T, Yoshida N, Kondo M.
Role of platelet-activating factor (PAF) in superoxide production by human polymorphonuclear leukocytes. Lipids 1991;26:1227-30.
346. Kondo M, Itani K, Yoshikawa T, Oyamada H, Ichikawa H, Kokura S, Tainaka K, Sugino S. [Chemoembolization with degradable starch microspheres for liver metastases of colorectal cancer]. Gan To Kagaku Ryoho 1991;18:535-40.
347. Kokura S, Yoshikawa T, Takahashi S, Oyamada H, Sugino S, Kondo M.
[Role of oxygen species and lipid peroxidation for anti-tumor effect of intra-arterial injection with degradable starch microspheres]. Gan To Kagaku Ryoho 348. Kawai T, Wada Y, Nishiyama K, Kanki Y, Ohga K, Oka T, Yasuda M, Yoshikawa T. [Usefulness of ulinastatin as a radical scavenger for protection of reperfusion injury after myocardial ischemia in open heart surgery]. Nippon Kyobu 349. Yoshikawa T, Ueda S, Takahashi S, Naito Y, Oyamada H, Morita Y, Tanigawa T, Takemura T, Sugino S, Kondo M. [Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats].
Nippon Shokakibyo Gakkai Zasshi 1990;87:8-15.
350. Yoshikawa T, Takeda S, Naito Y, Kondo M. Protective effects of ONO-3307, a new synthetic protease inhibitor against experimental disseminated intravascular coagulation in rats. Thromb Res 1990;60:1-7.
351. Yoshikawa T, Oyamada H, Ichikawa H, Naito Y, Ueda S, Tainaka K, Takemura T, Tanigawa T, Sugino S, Kondo M. [Role of active oxygen species and lipid peroxidation in liver injury induced by ischemia-reperfusion]. Nippon Shokakibyo Gakkai Zasshi 1990;87:199-205.
352. Yoshikawa T, Naito Y, Ueda S, Takahashi S, Oyamada H, Yoneta T, Sugino S, Kondo M. Ischemia-reperfusion injury and free radical involvement in gastric mucosal disorders. Adv Exp Med Biol 1990;264:401-10.
353. Yoshikawa T, Naito Y, Ueda S, Oyamada H, Takemura T, Yoshida N, Sugino S, Kondo M. Role of oxygen-derived free radicals in the pathogenesis of gastric mucosal lesions in rats. J Clin Gastroenterol 1990;12 Suppl 1:S65-71.
354. Yoshikawa T, Naito Y, Oyamada H, Ueda S, Tanigawa T, Takemura T, Sugino S, Kondo M. Scavenging effects of Aspalathus linealis (Rooibos tea) on active oxygen species. Adv Exp Med Biol 1990;264:171-4.
355. Yoshikawa T, Kondo M. [Free radicals in digestive diseases]. Nippon Ronen Igakkai Zasshi 1990;27:155-60.
356. Yoshikawa T, Kondo M. [Multiple organ failure and free radicals].
Nippon Naika Gakkai Zasshi 1990;79:1239-43.
357. Yoshikawa T, Kondo M. Free radicals in multiple organ failure. Jpn J Med 358. Yoshikawa H, Furuki J, Takahashi Y, Morioka H, Yoshida Y.
Freeze-fracture study of the bloodstream form of Trypanosoma brucei gambiense. J 359. Ueda S, Yoshikawa T, Takahashi S, Naito Y, Oyamada H, Takemura T, Morita Y, Tanigawa T, Sugino S, Kondo M. Protection by seleno-organic compound, Ebselen, against acute gastric mucosal injury induced by ischemia-reperfusion in rats. Adv Exp Med Biol 1990;264:187-90.
360. Tanigawa T, Yoshikawa T, Naito Y, Yoneta T, Ueda S, Oyamada H, Takemura T, Morita Y, Tainaka K, Yoshida N, et al. Antioxidative action of zinc-carnosine compound Z-103. Adv Exp Med Biol 1990;264:223-8.
361. Takemura T, Yoshikawa T, Naito Y, Ueda S, Tanigawa T, Sugino S, Kondo M. Role of xanthine-xanthine oxidase systems and polymorphonuclear leukocytes in lipid peroxidation in compound 48/80-induced gastric mucosal injury in rats. Adv Exp Med Biol 1990;264:415-8.
362. Naito Y, Yoshikawa T, Tanigawa T, Yoneta T, Ueda S, Oyamada H, Takemura T, Sugino S, Kondo M. Zinc-carnosine chelate compound (Z-103) attenuates acute gastric mucosal injury induced by ischemia-reperfusion in rats. Adv 363. Kokura S, Yoshikawa T, Kishi A, Tomii T, Tsujigiwa M, Yasuda M, Ichikawa H, Takano H, Takahashi S, Naito Y, et al. [Role of oxygen-derived free radicals for antitumor effects of intra-arterial injection with adriamycin]. Gan To 364. Hiraoka N, Yoshikawa T, Kondo M, Nishioka H, Goto I, Fukuoka J, Ohsawa A, Yokoh S. [Reduction in leukocyte elastase levels in patients with sepsis by administration of urinastatin]. Masui 1990;39:367-71.
365. Arizono N, Shiota T, Yamada M, Matsumoto Y, Yoshikawa H, Matsuda S, Tegoshi T. Bromodeoxyuridine labeling studies on the proliferation of intestinal mucosal mast cells in normal and athymic rats. Apmis 1990;98:369-76.
366. Yoshikawa T, Ueda S, Naito Y, Takahashi S, Oyamada H, Morita Y, Yoneta T, Kondo M. Role of oxygen-derived free radicals in gastric mucosal injury induced by ischemia or ischemia-reperfusion in rats. Free Radic Res Commun 367. Yoshikawa H, Yoshida Y. Ultrastructure of Pneumocystis carinii: a freeze-fracture study. J Protozool 1989;36:51S-52S.
368. Yoshikawa H, Yamada M, Matsumoto Y, Yoshida Y. Variations in egg size of Trichuris trichiura. Parasitol Res 1989;75:649-54.
369. Yoshikawa H, Tegoshi T, Yoshida Y. Detection of surface carbohydrates of Pneumocystis carinii. J Protozool 1989;36:63S-64S.
370. Yoshida Y, Shiota T, Yamada M, Yoshikawa H, Tegoshi T, Ikai T, Ogino K.
The present status of Pneumocystis carinii pneumonia in Japan with special reference to AIDS. J Protozool 1989;36:78S-80S.
371. Yoshida N, Yoshikawa T, Ando T, Naito Y, Oyamada H, Takemura T, Tanigawa T, Sugino S, Kondo M. Pathogenesis of platelet-activating factor-induced gastric mucosal damage in rats. Scand J Gastroenterol Suppl 1989;162:210-4.
372. Ueda S, Yoshikawa T, Takahashi S, Ichikawa H, Yasuda M, Oyamada H, Tanigawa T, Sugino S, Kondo M. Role of free radicals and lipid peroxidation in gastric mucosal injury induced by ischemia-reperfusion in rats. Scand J 373. Takemura T, Yoshikawa T, Yoshida N, Takano H, Tasaki N, Naito Y, Ueda S, Sugino S, Kondo M. Role of lipid peroxidation and oxygen radicals in compound 48/80-induced gastric mucosal injury in rats. Scand J Gastroenterol Suppl 374. Oyamada H, Yoshikawa T, Itani K, Ichikawa H, Tainaka K, Seto O, Sugino S, Kondo M. [Chemo-embolization using degradable starch microspheres and regional hyperthermia in unresectable hepatocellular carcinoma]. Gan To 375. Matsuda S, Urata Y, Shiota T, Yamada M, Yoshikawa H, Tegoshi T, Okada M, Nakamura H, Kitaoka T, Ashihara T, et al. Disseminated infection of Pneumocystis carinii in a patient with the acquired immunodeficiency syndrome.
Virchows Arch A Pathol Anat Histopathol 1989;414:523-7.
376. Kondo M, Yoshikawa T. [Role of free radicals in the treatment of cancer].
Gan To Kagaku Ryoho 1989;16:3655-61.
377. Itani K, Yoshikawa T, Oyamada H, Takano H, Ichikawa H, Tainaka K, Sugino S, Kondo M. [Chemoembolization with degradable starch microspheres for liver metastases in colorectal cancer]. Gan To Kagaku Ryoho 1989;16:2897-900.
378. Yoshikawa T, Yoshida N, Miyagawa H, Tanigawa T, Takemura T, Morita Y, Sugino S, Kondo M. Role of oxygen radicals in endotoxin shock and disseminated intravascular coagulation. Basic Life Sci 1988;49:933-40.
379. Yoshikawa T, Oyamada H, Itani K, Tainaka K, Seto O, Sugino S, Kondo M. [Chemoembolization and regional hyperthermia with degradable starch microspheres in the treatment of malignant hepatic tumors]. Gan To Kagaku Ryoho 380. Yoshikawa T, Giamalva DH, Flory W, Ruhr LP, Church DF, Pryor WA.
Toxicity of aromatic hydrocarbons. VII. Hepatotoxicity of 9-nitrophenanthrene, and protection against it by beta-naphthoflavone. Biochem Int 1988;16:935-40.
381. Yoshikawa T, Flory W, Giamalva DH, Ruhr LP, Church DF, Pryor WA.
Toxicity of polycyclic aromatic hydrocarbons. VI. Effects of 1-nitropyrene on serum enzyme levels in rats, and protection against it by beta-naphthoflavone and dimethyl sulfoxide. Biochem Int 1988;16:929-34.
382. Yoshikawa H, Yamada M, Yoshida Y. Freeze-fracture study of the trophozoite and the cyst of Entamoeba histolytica. J Protozool 1988;35:268-73.
383. Yoshikawa H, Yamada M, Yoshida Y. Freeze-fracture study of Blastocystis 384. Yoshikawa H, Morioka H, Yoshida Y. Ultrastructural detection of carbohydrates in the pellicle of Pneumocystis carinii. Parasitol Res 1988;74:537-43.
385. Naito Y, Yoshikawa T, Oyamada H, Tainaka K, Morita Y, Kogawa T, Sugino S, Kondo M. Esophageal candidiasis. Gastroenterol Jpn 1988;23:363-70.
386. Itani K, Yoshikawa T, Tainaka K, Oyamada Y, Sugino S, Kondo M, Seto O. [Effects of hyperthermia combined with chemoembolization using degradable starch microspheres in the treatment of hepatocellular carcinoma]. Gan To Kagaku 387. Itani K, Yoshikawa T, Oyamada Y, Tainaka K, Sugino S, Kondo M.
[Chemoembolization with degradable starch microspheres in metastatic liver cancer]. Gan To Kagaku Ryoho 1988;15:2606-10.
388. Yoshikawa T, Giamalva DH, Flory W, Ruhr LP, Church DF, Pryor WA.
Toxicity of polycyclic aromatic hydrocarbons. IV. Effects of diphenaldehyde, a major product of ozonized phenanthrene, in rats. Biochem Int 1987;15:139-46.
389. Yoshikawa T, Flory W, Giamalva DH, Ruhr LP, Church DF, Pryor WA.
Toxicity of polycyclic aromatic hydrocarbons. V. Protective effect of beta-naphthoflavone against hepatotoxicity induced by diphenaldehyde in rats.
390. Yoshikawa H, Yoshida Y. Freeze-fracture studies on Pneumocystis carinii.
III. Fine structure of the precyst and the cyst. Parasitol Res 1987;74:36-42.
391. Yoshikawa H, Yoshida Y. Localization of silver deposits on Pneumocystis carinii treated with Gomori's methenamine silver nitrate stain. Zentralbl Bakteriol 392. Yoshikawa H, Tegoshi T, Yoshida Y. Detection of surface carbohydrates on Pneumocystis carinii by fluorescein-conjugated lectins. Parasitol Res 393. Yamada M, Yoshikawa H, Tegoshi T, Matsumoto Y, Yoshikawa T, Shiota T, Yoshida Y. Light microscopical study of Blastocystis spp. in monkeys and fowls.

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