Material Safety Data Sheet HAZARDOUS Catalog Number: 103011 Revision date: 10-Mar-2005 Australia Hazardous Statement: Hazardous according to criteria of NOHSC 1. COMPANY DETAILS Supplier:
MP Biomedicals Australasia Pty Limited Unit 12, 167 Prospect Hwy. Seven Hills, NSW 2147 Aust. Telephone Number: Fax Number: Emergency telephone number:
(02) 9838 7422: hours: 8.30 AM to 5.00 PM
Australian Business Number 2. IDENTIFICATION Product name: Catalog Number: Synonyms: UN/Id No: Proper shipping name: IATA Hazard Label(s): Hazard Class Subsidiary risk: Emergency Action Code (Hazchem code): Poisons schedule No. (Aust)/Toxic Substance (NZ): Recommended use: Component Australia (AICS): 3. PHYSICAL DESCRIPTION/PROPERTIES Appearance and Odor Physical state: Formula: Molecular weight: Boiling point/range: Melting point/range: Density: Vapor pressure: Solubility (in water): Flash point: Catalog Number: 103011 Product name: TETRACYCLINE Page 1 of 6 HYDROCHLORIDE MP Biomedicals Australasia Pty Limited www.mpbio.com Autoignition temperature: Flammable limits in air - lower (%): Flammable limits in air - upper 4. INGREDIENTS Components CAS Number Classification 5. HAZARDS IDENTIFICATION Australia Hazardous Statement: Hazardous according to criteria of NOHSC Indication of Danger: Xn - Harmful. Risk Phrases: R22 - Harmful if swallowed. Safety Phrases: .
S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection.
Category of Danger: Harmful Poisons schedule No. (Aust)/Toxic Substance (NZ): S5 Caution. 6. HEALTH HAZARD INFORMATION HEALTH EFFECTS EMERGENCY OVERVIEW:
Harmful by inhalation, in contact with skin and if swallowed. Principle routes of exposure: Inhalation: Ingestion: Skin contact: Eye contact: Statements of hazard
HARMFUL IF SWALLOWED. MAY BE HARMFUL IF ABSORBED THROUGH SKIN OR INHALED. Components Australian Exposure Standards - Australia - Exposure Standards - Short Carcinogens Catalog Number: 103011 Product name: TETRACYCLINE Page 2 of 6 HYDROCHLORIDE MP Biomedicals Australasia Pty Limited www.mpbio.com Components Australia - Exposure Standards - Skin E Australia - Exposure Standards - Time W FIRST AID General advice:
In the case of accident or if you feel unwell, seek medical advice immediately (show the label where possible). Inhalation:
Move to fresh air. Call a physician immediately. Skin contact:
Rinse immediately with plenty of water and seek medical advice
Ingestion:
Do not induce vomiting without medical advice. Eye contact:
In the case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Protection of first-aiders: Notes to physician: Medical conditions aggravated by None known exposure:
7. PRECAUTIONS FOR USE Section 8 Notes: TWA - The time-weighted average airborne concentration over an eight-hour working day, for a five- day working week over an entire working life. According to current knowledge this concentration should neither impair the health or, not cause undue discomfort to, nearly all workers. Engineering measures: Ensure adequate ventilation. PERSONAL PROTECTIVE EQUIPMENT
Respiratory protection: Self-contained breathing apparatus Hand protection: Pvc disposable gloves Skin and body protection: Usual safety precautions while handling the product will provide adequate protection against this potential effect. Eye protection: Safety glasses Hygiene measures: Avoid contact with skin, eyes and clothing. 8. SAFE HANDLING INFORMATION Storage: Handling:
Use only in area provided with appropriate exhaust ventilation. Safe handling advice: Stability:
Stable under recommended storage conditions. Polymerization: Hazardous decomposition
Chloride/Hydrochloric acid Nitrogen oxides (NOx)/ammonia/CN-
products: Materials to avoid: Conditions to avoid:
Exposure to air or moisture over prolonged periods. Catalog Number: 103011 Product name: TETRACYCLINE Page 3 of 6 HYDROCHLORIDE MP Biomedicals Australasia Pty Limited www.mpbio.com Spills and Disposal: Personal precautions: Environmental precautions:
Prevent product from entering drains. Methods for cleaning up:
Sweep up and shovel into suitable containers for disposal. Waste from residues / unused products:
Waste disposal must be in accordance with appropriate Federal, State, and local regulations. This product, if unaltered by use, may be disposed of by treatment at a permitted facility or as advised by your local hazardous waste regulatory authority. Residue from fires extinguished with this material may be hazardous.
Contaminated packaging: Fire/Explosion Hazards: Suitable extinguishing media:
Use dry chemical, CO2, water spray or "alcohol" foam
Specific hazards: Unusual hazards: Special protective equipment for firefighters:
As in any fire, wear self-contained breathing apparatus pressure-demand, MSHA/NIOSH (approved or equivalent) and full protective gear
Specific methods:
Water mist may be used to cool closed containers. 9. TOXICOLOGICAL INFORMATION Product Information Acute toxicity Components RTECS Number: Selected LD50s and LC50s
Oral LD50 Rat : 6443 mg/kgOral LD50 Mouse : 2759 mg/kg
Chronic toxicity:
Chronic exposure may cause nausea and vomiting, higher exposure causes unconsciousness. Local effects:
Symptoms of overexposure may be headache, dizziness, tiredness, nausea and vomiting. Specific effects:
May include moderate to severe erythema (redness) and moderate edema (raised skin), nausea, vomiting, headache. Carcinogenic effects:
No data is available on the product itself. Mutagenic effects:
Substances which cause concern for man owing to possible mutagenic effects but for which the available information is not adequate for making a satisfactory assessment. Reproductive toxicity:
No data is available on the product itself. 10. ECOLOGICAL INFORMATION Mobility: Bioaccumulation: Ecotoxicity effects: Aquatic toxicity:
May cause long-term adverse effects in the aquatic environment. Components U.S. DOT - Appendix B - U.S. DOT - Appendix B - United Kingdom - The Red Marine Pollutan Severe Marine Pollutants Catalog Number: 103011 Product name: TETRACYCLINE Page 4 of 6 HYDROCHLORIDE MP Biomedicals Australasia Pty Limited www.mpbio.com Components Germany VCI (WGK) World Health Organization Ecotoxicity - Fish Species (WHO) - Drinking Water Components Ecotoxicity - Freshwater Ecotoxicity - Microtox Data Ecotoxicity - Water Flea Algae Data Components EPA - ATSDR Priority List EPA - HPV Challenge California - Priority Toxic Program Chemical List Pollutants Components California - Priority Toxic Pollutants California - Priority Toxic Pollutants 11. TRANSPORT INFORMATION IMDG/IMO
Proper shipping name: Australia Hazardous Statement: ADR/RID-labels: Emergency Action Code (Hazchem code): Proper shipping name: Proper shipping name: 12. REGULATORY INFORMATION International inventories:
TETRACYCLINE HYDROCHLORIDE Australia (AICS): Inventory - China: Catalog Number: 103011 Product name: TETRACYCLINE Page 5 of 6 HYDROCHLORIDE MP Biomedicals Australasia Pty Limited www.mpbio.com EU EINECS List - Korean KECL: Philippines PICCS: Present Indication of Danger: Xn - Harmful. Risk Phrases: R22 - Harmful if swallowed. Safety Phrases: . Safety Combination Phrases: S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. Poisons schedule No. (Aust)/Toxic Substance (NZ): S5 Caution. 13. OTHER INFORMATION Prepared by: Health & Safety Disclaimer: The information and recommendations contained herein are based upon tests believed to be reliable. However, MP Biomedicals does not guarantee the accuracy or completeness NOR SHALL ANY OF THIS INFORMATION CONSTITUTE A WARRANTY, WHETHER EXPRESSED OR IMPLIED, AS TO THE SAFETY OF THE GOODS, THE MERCHANTABILITY OF THE GOODS, OR THE FITNESS OF THE GOODS FOR A PARTICULAR PURPOSE. Adjustment to conform to actual conditions of usage maybe required. MP Biomedicals assumes no responsibility for results obtained or for incidental or consequential damages, including lost profits arising from the use of these data. No warranty against infringement of any patent, copyright or trademark is made or implied. End of Safety Data Sheet Catalog Number: 103011 Product name: TETRACYCLINE Page 6 of 6 HYDROCHLORIDE
Yasuyuki Ishikawa E-mail: yishikawa@uprrp.edu Date of Birth: Oct. 10, 1947(naturalized U.S. citizen): Marital Status: Married, one child Education Tokyo Institute of Technology, Japan, B.S. in Chemistry 1971 University of Iowa, Iowa City, Iowa, Ph.D. in Chemistry 1976 Employment Professor of Chemistry University of Puerto Rico, Rio Piedras IMS Visiting Professor University of Puerto Rico, Ri
Acidemia A condition in which the blood is more acid and lessAortic arch The second part of the aorta, which continues onAcidosis An abnormal condition resulting from an increase infrom the ascending aorta and curves to the left and poste-acids or from a depletion of alkali in the blood and bodyAortic valve The valve in the heart between the left ventricleAcute A term used to describe a cond
Material Safety Data Sheet
MP Biomedicals Australasia Pty Limited
MP Biomedicals Australasia Pty Limited
MP Biomedicals Australasia Pty Limited