Kamagra enthält Sildenafilcitrat als pharmakologisch aktiven Bestandteil. Dieser hemmt selektiv die Phosphodiesterase-5 und erhöht dadurch die Konzentration von cGMP im Corpus cavernosum. Der Effekt ist zeitlich begrenzt, da die Halbwertszeit von Sildenafil etwa vier Stunden beträgt. In der galenischen Form als Mundgel erfolgt die Resorption besonders rasch, was zu einem schnelleren Wirkeintritt führt. Der Abbau erfolgt überwiegend hepatisch über CYP3A4, wobei ein aktiver Metabolit entsteht, der zur Gesamtwirkung beiträgt. Typische Nebenwirkungen ergeben sich aus der Vasodilatation, darunter leichte Kopfschmerzen und nasale Kongestion. In klinischen Beschreibungen wird kamagra oral jelly im Zusammenhang mit der schnelleren Absorption erwähnt.
Microsoft word - program
Symposium for Rheumatologists, Immunologists and Pediatricians (in French):
Maladies fébriles récurrentes et syndromes auto-inflammatoires :
Diagnostic et traitement de l’enfant à l’adulte
Young Investigators Meeting Opening Ceremony: Jurg Tschopp Memorial Lecture:
What’s new in auto-inflammation since 2010? : Michael McDermott,
Tribute to Jurg Tschopp: Fabio Martinon, Epalinges, Switzerland
Welcome Reception Joost Frenkel: News on the treatment of HIDS
François Spertini: Adverse events and allergic responses to
Session 1: CAPS and inflammasome
Update on IL-1 dysregulation, Charles Dinarello, Denver, USA
NLRs, Basic mechanism of action and relevance in diseases: Jenny
Mutation negative CAPS: Joost Frenkel, Utrecht, Netherlands
Coffee break Session 2: FMF
SAA, amyloidosis and cell damage: Bouke Hazenberg, Groningen,
FMF heterozygotes: Véronique Hentgen, Versailles, France
Treatment of FMF in 2013: Seza Ozen, Ankara, Turkey
Session 3: Granulomatous diseases
Physiopathology of granuloma: Frédéric Altare, Nantes, France
Immunodeficiency and Granulomatosis: Alexandre Belot, Lyon,
Auto-inflammatory granulomatous diseases: Carine Wouters,
Workshops
1. Genetic: Taxonomy of hereditary auto-inflammatory diseases:
Eldad Ben Chetrit, Jerusalem, Israel
2. Biomarkers (S100A proteins, cytokines, CRP-SAA)
Dirk Holzinger, Münster, Germany
3. Patient oriented research techniques in the auto-inflammatory
Coffee break Session 4: Monogenic autoinflammatory diseases
ER and stress: Fabio Martinon, Epalinges, Switzerland
Immunoproteosome: Ivona Aksentijevitch, Bethesda, USA
New monogenic auto-inflammatory periodic syndromes: Marco PRO-CON: Controversies on the mode of inheritance of AIDs Isabelle Touitou, Montpellier, France and Michael Morris, Geneva,
Jasmine Kummerle-Deschner: Practical diagnostic aspects of CAPS
Anna Simon: Triggering causes for AID and attack prevention
Seza Ozen: Practical aspects of FMF treatment
Hans Acha-Orbea: Inflammasome activation in different diseases
Session 5: Non-monogenic AIDs
Genome wide association studies in polygenic AIDs: Dan Kastner,
Chronic recurrent multifocal osteomyelitis: Hermann Girschick,
PFAPA Syndrome: Michaël Hofer, Lausanne, Switzerland
Coffee break Session 6+7: Abstract presentations Coffee break Session 8: Systemic-onset JIA and AOSD
Update on the pathophysiology of So-JIA and AOSD: Virginia
Update on the treatment of So-JIA in 2013: Rolando Cimaz,
PRO-CON: Prednisone versus Biotherapy in early treatment of So- Alberto Martini, Genoa, Italy / Nico Wullfraat, Utrecht, Netherland
Jasmine Kummerle-Deschner: Long-term CAPS treatment by anti-
Anna Simon: How to do research on diseases with intermittent
Rolando Cimaz: Practical aspects of biotherapies in SOJIA
Mike Morris: Guidelines for genetic diagnosis of hereditary fevers
Alexander So: Microcristals and inflammation
Session 9: Behçet
Pathogenesis of Behcet's disease: HLA and beyond: Ahmed Gül,
Treatment of Behçet’s uveitis: Yan Guex-Crosier, Lausanne,
Behçet registry, PED-BD: Isabelle Kone-Paut, Kremlin-Bicêtre,
Coffee break Session 10+11: Abstract presentations Session 12: New developments in auto-inflammation: new diseases and therapeutic targets
Diabetes and auto-inflammation, Mark Donath, Zurich Switzerland
Auto-inflammation in the skin, psoriasis: Michel Gilliet, Lausanne,
New targets for the treatment of auto-inflammatory diseases:
Coffee break Session 13: Late breaking abstracts Congress dinner Session 14: New developments in auto-inflammation: from regulation to biotherapies
Regulatory cytokines and cells dampening (auto-) inflammation:
Side effects of biotherapies, novel aspects: David Isenberg, London,
Coffee break Session 15: Difficult case presentations
BIOGRAPHICAL SKETCH Provide the following information for the key personnel and other significant contributors. Follow this format for each person. DO NOT EXCEED FOUR PAGES. EDUCATION/TRAINING (Begin with baccalaureate or other initial professional education, such University of Western Ontario, London ON A. Positions and Honors. Positions and Employment 1989-1991 Head, Cli
HARDWARE DATA AND PROGRAM REPRESENTATION Chapter Objective 1: Most digital computers work in a two-state, or binary , fashion. It is convenient to think ofthese binary states in terms of 0s and 1s. Computer people refer to these 0s and 1s as bits . Converting data to these 0s and 1s is called digital data representation . While most individuals use the decimal number system to