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The treatment of urolithiasis with tamsulosine
I. Haxhiu1, X. Quni1, S. Hyseni1, H. Aliu1, A. Haxhiu2, E. Haxhiu2
1 Urology Department, University Clinical Center of Kosovo, Prishtina, Kosovo
2 Medical Faculty, University of Prishtina, Prishtina, Kosovo
Introduction and Objectives:
Tamsulosin is anselectivewhich can be used, besides for
BPE, also in the treatment of urolithiasis, respectively uromicrolithiasis.
Our purpose is to give a picture of the effect of tamsulosine in the treatment, respectively elimination of
uroliths. Material and Methods:
Our paper is a perspective study, which includes a period time of May 2008 until
May 2011. Patients are divided in two groups: 220 of them were treated with tamsulosine and analgetics
(Diclofenac), for two, respectively four weeks and 120 other patients (control groups), were treated only
with analgetics and superhydration. The size of uroliths varies of 5 to 10 mm. Diagnoses were decided with
ultrasounds or uropyelography.
The material has been collected in the Private Urologic Policlinics “Pro-Ren” in Ferizaj and University Clinical
Center of Kosovo, in Pristina. Results:
70 cases (31.8%) from the first group, whose stones are localized in the kidney, respectively
calyces and pelvis, with sizes of 5-7 mm, only five of them have sizes above 7 mm, respectively three of
them had sizes of 9 mm and two others with 10 mm. Elimination of uroliths happened in 65 cases,
respectively in 92.8%, inside two-four weeks, from the moment they started applying tamsulosine.
Meanwhile the other 5 cases (7.2%), additional methods were necessary: ESWL, respectively, application of
J-J stents.; 90 of the patients or 40.9%, with uroliths in proximal part of the ureters (from U-P junction until
pelvic part of the ureter), with sizes of 5-7 mm, in 85 cases or 89%, have eliminated uroliths, only with use
of tamsulosine for 2-4 weeks, meanwhile in 5 cases (5.5%), additional methods were necessary, respectively
URS-lithotripsy in three cases (3.3%) and application of J-J stents, in two cases (2.2%). In 60 cases
(27.7%), with uroliths in distal part of ureters (pelvic and intramural parts), with sizes of 5-7 mm, the
uroliths were eliminated in 57 cases or 95%, by using tamsulosine and analgetics (Diclofenac) and in three
cases (5%) the J-J stents were applied.
The other control group made of 120 cases, resulted with spontaneous elimination of uroliths in 40 cases or
(33.58%) and in 80 cases (66.42%), additional methods like J-J stents or URS- lithotripsy were applied. Conclusions:
Of above mention results, we can see that tamsulosine, as selective is a
medication with strong effect in elimination of uroliths, sizes from 5 -7 mm, so we prefer to use it widely and
results are very encouraging, in this direction.
SIU UK Section Meeting (London-UK •
November 22, 2013)
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