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Form 34qr march 2005.pub

PARENT RATINGS OF BEHAVIORAL EFFECTS OF BIOMEDICAL INTERVENTIONS
Autism Research Institute ● 4182 Adams Avenue ● San Diego, CA 92116
The parents of autistic children represent a vast and important reservoir of information on the benefits—and adverse effects— of the large variety of drugs and other interventions that have been tried with their children. Since 1967 the Autism Research Institute has been collecting parent ratings of the usefulness of the many interventions tried on their autistic children. The following data have been collected from the more than 23,700 parents who have completed our questionnaires designed to collect such information. For the purposes of the present table, the parents responses on a six-point scale have been combined into three categories: “made worse” (ratings 1 and 2), “no effect” (ratings 3 and 4), and “made better” (ratings 5 and 6). The “Better:Worse” column gives the number of children who “Got Better” for each one who “Got Worse.” Parent Ratings
Parent Ratings
Parent Ratings
Got No Got Better: No. of
Got No Got Better: No. of
Got No Got Better: No. of
WorseA Effect Better Worse CasesB DRUGS
WorseA Effect Better Worse CasesB
DRUGS WorseA Effect Better Worse CasesB
25% 34% 0.8:1
Desipramine 34% 31% 34% 1.0:1
Phenobarb.D
Amphetamine 47%
28% 25% 0.5:1
DilantinD
Behavior
Anafranil
38% 30% 1.0:1
Behavior
Seizures
Antibiotics
57% 12% 0.4:1
Seizures
Prolixin
AntifungalsC
Felbatol
Diflucan
41% 55% 11:1
Fenfluramine 20% 52% 28% 1.4:1
Risperidal
Nystatin
46% 49% 10:1
53% 22% 0.9:1
Secretin
Benadryl
51% 25% 1.0:1
Intravenous 7%
Beta Blocker 18%
50% 33% 1.9:1
KlonapinD
Transderm. 10%
44% 30% 1.1:1
Behavior
Stelazine
Seizures
TegretolD
38% 21% 0.5:1
Behavior
Clonidine
31% 47% 2.2:1
Seizures
Clozapine
42% 18% 0.4:1
Mellaril
Thorazine
Cogentin
54% 27% 1.5:1
MysolineD
Tofranil
35% 20% 0.4:1
Behavior
56% 30% 2.0:1
Seizures
ZarontinD
DepakeneD
Naltrexone
Behavior
Behavior
43% 32% 1.2:1
Seizures
Seizures
32% 57% 4.8:1
Phenergan
BIOMEDICAL/
Parent Ratings
BIOMEDICAL/
Parent Ratings
NON-DRUG/
Got No Got Better: No. of
NON-DRUG/
Got No Got Better: No. of
SUPPLEMENTS
WorseA Effect Better Worse CasesB
SUPPLEMENTS
WorseA Effect Better Worse CasesB
Vitamin A
Vitamin B3
55% 41% 10:1
CalciumE
Vit. B6 alone
63% 30% 3.9:1
Cod Liver Oil
Vit. B6/Mag.
49% 47% 10:1
Cod Liver Oil with
Vitamin B12
33% 63% 15:1
Bethanecol
45% 39% 2.4:1
Vitamin C
57% 41% 18:1
Colostrum
58% 37% 8.1:1
51% 47% 20:1
Detox. (Chelation)C
Digestive Enzymes
SPECIAL DIETS
51% 42% 5.6:1
Fatty Acids
Candida Diet
51% 39% 3.7:1
Feingold Diet
Folic Acid
Gluten- /Casein-
Food Allergy Trtmnt
Free Diet
Magnesium
65% 29% 4.6:1
Melatonin
30% 61% 7.3:1
Chocolate
P5P (Vit. B6)
37% 51% 4.0:1
Removed Eggs
63% 28% 3.2:1
Removed Milk
66% 19% 1.3:1
Products/Dairy
St. Johns Wort
64% 21% 1.5:1
Removed Sugar
44% 42% 3.0:1
Removed Wheat
Transfer Factor
Rotation Diet
A. “Worse” refers only to worse behavior. Drugs, but not nutrients, typically also cause physical problems if used long-term. B. No. of cases is cumulative over several decades, so does not reflect current usage levels (e.g., Haldol is now seldom used). C. Antifungal drugs and chelation are used selectively, where evidence indicates they are needed. D. Seizure drugs: top line behavior effects, bottom line effects on seizures E. Calcium effects are not due to dairy-free diet; statistics are similar for milk drinkers and non-milk drinkers.

Source: http://www.sharpermindcenters.com/autism/parents_rating_of_behavioral_effects_of_interventions.pdf

Obst.6.06.(12).av•

REV CHIL OBSTET GINECOL 2006; 71(6): 437-439Betametasona antenatal e incidencia de distrés respiratorio despuésde cesárea electiva: estudio aleatorizado pragmático (1)Stutchfield P, Whitaker R, Russell I. Antenatal Steroids for Term Elective Caesarean Section (ASTECS)Research Team. BMJ 2005; 331: 662-8. Análisis crítico: BERNARDITA DONOSO B., CLAUDIO VERA P-G., JORGE CARVAJAL C., PhD. Uni

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