Swami Ramanand Teerth Marathwada University, B. O. S. In Chemistry B. Sc. Second Year Semester-I & II Dyes and Drugs In force from June - 2010 B. Sc. Second Year (Semester I & II) DYES AND DRUGS Syllabus Semester Paper
action on CNS Synthesis and Application of
CHDD-203 methane, anthraquinone, xanthenes
and Heterocyclic Dyes. Synthesis and Application of DYES AND DRUGS Semester – III Paper: VI Synthesis, Application fastness properties of azo and Azoic Dyes (CHDD-201) Marks:60 Periods:45 UNIT I I. Action of light on dyes and dyed fibres 10 periods
Factors affecting fastness of dyed fibres
a. General consideration b. fluorescence, phototropy, mechanism of fading
Constitution of dyes and light fastness with respect to Nitro dyes, Azo dyes, basic
dyes, sulphur dyes, Indigo dyes, anthraquinones.
UNIT II I. Azo-Dyes – Synthesis and applications : 10 periods
(vii) Metanil yellow (viii) Aniline yellow
(xii) Chromotrope 2B (xiii) Erichrome black T UNIT III I. Dyeing and fastness properties of azo dyes 10 periods
1) General consideration 2) Dyeing and fastness properties of
a) Azodyes for wool b) Azodyes for silk c) Azodyes for leather d) Direct cotton dyes e) Acid colours on cotton
UNIT IV I. Azoic Dyes : 15 periods
1) Introduction, Chemical constitution of napthols. 2) Preparation of Napthols, Napthols for yellow shade, azoic shades. 3) Steps involved in azoic dyeing. 4) Application of azoic dyes on fibres other than cotton (wool, silk, cellulose, acetate) 5) Fastness properties of azoic shades top light, chlorine, rubbing, alkali. 6) Azoic colours in printing, printing composition. Types of azoic colours in printing.
DYES AND DRUGS Semester – III Paper: VII Synthesis and Application of Drugs acting on CNS (CHDD-202) Marks:60 Periods:45 UNIT I I. Anaesthetics 15 periods
1) Introduction and Classification of anesthetics. 2) Characteristics of ideal anesthetics. 3) Study of volatile general anesthetics
4) Study of non-volatile general anesthetics
i) α - Eucatine, ii) orthocaine, iii) Benzocaine, iv) procaine v) xylocaine
UNIT II I. Study of sedatives and hypnotics and Anticonvulsants 10 periods
1) Introduction and Classification of sedatives and hypnotics and Anticonvulsants 2) Synthesis and applications of
x) urethene, xi) phenobarbitone, xii) Pentabarbitone
UNIT III I. Study of Tranquillizer (selective Modifiers of CNS) 10 periods
1) Introduction and Classification of Tranquillizer (selective Modifiers of CNS) 2) Synthesis and applications of
ii) Prochlorperazine iii) Chlorprothixene iv) Thiothixene
UNIT IV I. Study of analgesics, antipyretics and anti-inflammatory 10 periods
1) Introduction and classification of analgesics, antipyretics and anti-inflammatory. 2) Mechanism of action of analgesics 3) Mechanism of action of antipyretics 4) Synthesis and applications of
x) Oxyphenylbutazone xi) phenylbutazone xii) ketoprofen
DYES AND DRUGS Semester – IV Paper: VIII Synthesis and Application of Methane, Anthraquinone, Xanthenes and Heterocyclic Dyes (CHDD-203) Marks:60 Periods:45 I. Diphenyl and triphenyl methane dyes : 15 periods
1. Diphenyl methane dyes : Introduction, synthesis and application of
2. Triphenyl methane dyes : Introduction. Classification, General properties, constitution of Triphenyl methane dyes (w.r.t. pararosaniline) 3. Synthesis and applications of following triphenyl methane dyes
4. Phenolphthalein – Synthesis, properties and application. UNIT II I. Anthraquinone Dyes : 10 periods
1) Introduction and classification of Anthraquinone Dyes 2) Synthesis and applications of dyes
v) Alizarin cyanine green vi) Indanthrene blue vii) Flavanthrene viii) Pyranthrene
I. Xanthene Dyes: 10 periods
1) Introduction, classification and General properties of Xanthene Dyes 2) Synthesis and applications of dyes
UNIT IV I. Heterocyclic Dyes : 10 periods
1) Introduction and Classification of heterocyclic dyes 2) Synthesis and applications of
DYES AND DRUGS Semester – IV Paper: IX Synthesis and Application of Chemotherapeutic Drugs (CHDD-204) Marks:60 Periods:45 I. Sulphonamides: 10 periods
1) Introduction and discovery of sulphonamides. 2) Classification of sulphonamides. 3) Mechanism of action of sulpha drug. 4) Synthesis and applications of following sulphonamides
vii) Succinyl Sulphathiazole, viii) Sulphaceamide
II. Antimalerials 10 periods
1) Introduction and historical background of antimalerials Classification 2) Classification of antimalerials 3) Pathogenecity and Chemotherapy of malarial parasite 4) Study of the following antimalerials with uses :
I. Antiseptics: 10 periods
1) Introduction and classification of antiseptics, 2) standardization of disinfactant (Phenol coefficient) 3) Study of following antispetics,
I. Antibiotics: 15 periods
1) Introduction, history of discovery of antibiotic. 2) classification of antibiotics 3) Study of following antibiotics with an introduction, production, isolation, properties, clinical uses and mechanism of action. i) Penicillin
4) Structure, activity, relationship of chloramphenicol and penicillin
B.Sc. IIyear DYES AND DRUGS LABORATORY COURSE III (CHDD-205) Marks: 100 Periods: 120
(Any sixteen experiments are to be covered)
1. Preparation of dye intermediates
a. Anthraquinone b. Aniline c. P-Bromo acetanalide
d. Succinic anhydride e. Sulphanillic acid f. P-Benzoquinone
2. Preparation of dyes :
a. Fluorescein b. Eosin c. Methyl orange II
3. Estimation of following Aryl amines by using NaNO solution
a. Aniline b. P-Nitroaniline c. P-chloro aniline
4. Dyeing methods
a. Direct dyeing of wool and silk with Orange II
b. Direct dyeing of wool and silk with Eosin
c. Direct dyeing of wool and silk with Malachite green
d. Direct dyeing of wool and silk with Crystal violet
e. Direct dyeing of cotton with congo red
f. Dyeing of cotton with Malachite green by Mordant dyeing method
h. Dyeing of cotton by vat dyeing method
B.Sc. IIyear DYES AND DRUGS Paper: XI LABORATORY COURSE IV (CHDD-206) Marks: 100 Periods: 120
(Any sixteen experiments are to be covered)
1. Preparation of Drug Intermediates 2. Preparation of Drugs
a. Antipyrine b. Methyl salicylate c. sulphonamide
3. Assay of Drugs
a. Aspirin b. Sulphonamide C. Paracetamol
4. Tests for Identity and purity of Drugs
Analgin, Aspirin, Vitamin C, Pencillin G, Chlorocresol, Chloroform, Chloroquine
phosphate, Cresol, Erythromycin, Isoniazide, sulphadiazine
5. Limit tests for chloride and sulphate for three drug samples
6. Qualitative Tests
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Journal of Vestibular Research 17 (2007) 1–8Effects of fluvoxamine on anxiety,depression, and subjective handicaps ofchronic dizziness patients with or withoutneuro-otologic diseasesArata Horii ∗ , Atsuhiko Uno, Tadashi Kitahara, Kenji Mitani, Chisako Masumura, Kaoru Kizawa andTakeshi Kubo Department of Otolaryngology, Osaka University School of Medicine, Osaka, Japan Abstract . A prospe